Nancy E. Hynes
Active 1977–2020
- 85
- Papers
- 23,355
- Citations
- 81
- h-index
- 85
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Medicine57.6%
- Biochemistry, Genetics and Molecular Biology32.7%
- Immunology and Microbiology2.8%
- Neuroscience1.6%
- Nursing1.1%
- Chemistry1%
- Other3.2%
Topics
- HER2/EGFR in Cancer Research11.2%
- Monoclonal and Polyclonal Antibodies Research7.1%
- Lung Cancer Treatments and Mutations2.9%
- Cytokine Signaling Pathways and Interactions2.5%
- Glycosylation and Glycoproteins Research2.5%
- Cell Adhesion Molecules Research2.3%
- Other71.5%
Coauthors
- Bernd Groner21
- Diana Graus-Porta11
- Roger R. Beerli10
- Heidi A. Lane9
- J.M. Daly6
- Monilola A. Olayioye6
- Richard M. Neve6
- Ali Badache5
- Barbara Marte5
- Thomas Holbro5
- Daniela Taverna4
- Fortunato Ciardiello4
- Iwan Beuvink4
- Winfried S. Wels4
- Yosef Yarden4
- Albana Gattelli3
- Andréa Barretto Motoyama3
- Anne Boulay3
- Daniel Heß3
- David S. Salomon3
- Francisca Maurer3
- Ina Maria Harwerth3
- Rob Michalides3
- Susanne Lienhard3
All papers
- ERBB receptors and cancer: the complexity of targeted inhibitors
Authors: Nancy E. Hynes, Heidi A. Lane - Nature reviews. Cancer 2005 cited by 3,310
- The ErbB signaling network: receptor heterodimerization in development and cancer
Authors: Monilola A. Olayioye, Richard M. Neve, Heidi A. Lane, Nancy E. Hynes - The EMBO Journal 2000 cited by 2,439
- ErbB‐2, the preferred heterodimerization partner of all ErbB receptors, is a mediator of lateral signaling
Authors: Diana Graus-Porta, Roger R. Beerli, J.M. Daly, Nancy E. Hynes - The EMBO Journal 1997 cited by 1,576
- ErbB receptors and signaling pathways in cancer
Authors: Nancy E. Hynes, Gwen MacDonald - Current Opinion in Cell Biology 2009 cited by 980
- The ErbB2/ErbB3 heterodimer functions as an oncogenic unit: ErbB2 requires ErbB3 to drive breast tumor cell proliferation
Authors: Thomas Holbro, Roger R. Beerli, Francisca Maurer, Magdalena Koziczak, Carlos F. Barbas, Nancy E. Hynes - National Academy of Sciences, Proceedings of the National Academy of Sciences 2003 cited by 960
- ErbB Receptors: Directing Key Signaling Networks Throughout Life
Authors: Thomas Holbro, Nancy E. Hynes - The Annual Review of Pharmacology and Toxicology 2004 cited by 632
- Memo Is a Copper-Dependent Redox Protein with an Essential Role in Migration and Metastasis
Authors: Gwen MacDonald, Ivan Nalvarte, Т. А. Смирнова, Manuela Vecchi, Nicola Aceto, Arno Doelemeyer, Anna Frei, Susanne Lienhard, Jeffrey Wyckoff, Daniel Heß, Jan Seebacher, J.J. Keusch, H. Gut, Danièle Salaün, Giovanni Mazzarol, Davide Disalvatore, Mohamed Bentires‐Alj, Pier Paolo Di Fiore, Ali Badache, Nancy E. Hynes - Science Signaling 2014 cited by 156
- Decreased NK-cell tumour immunosurveillance consequent to JAK inhibition enhances metastasis in breast cancer models
Authors: Alessia Bottos, Dagmar Gotthardt, Jason Gill, Albana Gattelli, Anna Frei, Alexandar Tzankov, Veronika Sexl, Aleksandra Wodnar‐Filipowicz, Nancy E. Hynes - Nature Communications 2016 cited by 105
- The ErbB-2/HER2 oncoprotein of human carcinomas may function solely as a shared coreceptor for multiple stroma-derived growth factors
Authors: Leah N. Klapper, Stefanie Glathe, Nora Vaisman, Nancy E. Hynes, Glenn C. Andrews, Michael Sela, Yosef Yarden - National Academy of Sciences, Proceedings of the National Academy of Sciences 1999 cited by 446
- The role of overexpressed HER2 in transformation
Authors: Richard M. Neve, Heidi A. Lane, Nancy E. Hynes - Annals of Oncology 2001 cited by 173
- The Serine Protease Inhibitor Protease Nexin-1 Controls Mammary Cancer Metastasis through LRP-1–Mediated MMP-9 Expression
Authors: Bérengère Fayard, Fabrizio Bianchi, Julien H. Dey, Eliza Moreno, Sabrina Djaffer, Nancy E. Hynes, Denis Monard - Cancer Research 2009 cited by 139
- NADPH oxidase-mediated redox signaling promotes oxidative stress resistance and longevity through memo-1 in C. elegans
Authors: Collin Y. Ewald, John M Hourihan, Monet S. Bland, Carolin Obieglo, Iskra Katic, Lorenza E Moronetti Mazzeo, Joy Alcedo, T. Keith Blackwell, Nancy E. Hynes - eLife 2017 cited by 87
- The biology of erbB-2/nue/HER-2 and its role in cancer
Authors: Nancy E. Hynes - Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 1994 cited by 972
- Interleukin 6 inhibits proliferation and, in cooperation with an epidermal growth factor receptor autocrine loop, increases migration of T47D breast cancer cells.
Authors: Ali Badache, Nancy E. Hynes - 2001 cited by 193
- ErbB‐2 is a common auxiliary subunit of NDF and EGF receptors: implications for breast cancer.
Authors: Devarajan Karunagaran, Eldad Tzahar, Roger R. Beerli, Xiomei Chen, Diana Graus-Porta, Barry Ratzkin, Rony Seger, Nancy E. Hynes, Yosef Yarden - The EMBO Journal 1996 cited by 674
- Pharmacological inhibition of fibroblast growth factor (FGF) receptor signaling ameliorates FGF23-mediated hypophosphatemic rickets
Authors: Simon Wöhrle, Christine Henninger, Olivier Bonny, Anne Thuery, Noémie Beluch, Nancy E. Hynes, Vito Guagnano, William R. Sellers, Francesco Hofmann, Michaela Kneissel, Diana Graus Porta - Journal of Bone and Mineral Research 2012 cited by 147
- Mammary Gland Growth Factors: Roles in Normal Development and in Cancer
Authors: Nancy E. Hynes, Christopher J.E. Watson - Cold Spring Harbor Perspectives in Biology 2010 cited by 114
- Knowledge gaps in oncoplastic breast surgery
Authors: William P. Weber, Monica Morrow, Jana de Boniface, Andrea L. Pusic, Giacomo Montagna, Elisabeth A. Kappos, Mathilde Ritter, Martin Haug, Christian Kurzeder, Ramon Saccilotto, Alexandra Schulz, John R. Benson, Florian Fitzal, Zoltán Mátrai, Jane Shaw, Marie‐Jeanne Vrancken Peeters, Shelley Potter, Joerg Heil, Eduardo González, Mona Elzayat, Rupert Koller, Michael Gnant, Fabrício Palermo Brenelli, Régis Resende Paulinelli, Vappu Zobel, Sarianna Joukainen, Ulla Karhunen‐Enckell, Susanna Kauhanen, Jean-Marc Piat, Vesna Bjelic‐Radisic, Andreé Faridi, Christoph Heitmann, Juergen Hoffmann, Ulrich Kneser, Sherko Kümmel, Thorsten Kühn, Michalis Kontos, Ekaterini Christina Tampaki, Mitchel Barry, Tanir M. Allweis, Moshe Carmon, Tal Hadar, Giuseppe Catanuto, Carlos A. Garcia‐Etienne, Oreste Gentilini, Susan Knox, Barbara C. Klein, Linetta B. Koppert, Pedro Gouveia, Tor Svensjö, Heiner C. Bucher, S.M. Ess, Ursula Ganz-Blättler, Andreas R. Günthert, Nik Hauser, Nancy E. Hynes, Michael Knauer, M Pfeiffer, Christoph Rochlitz, Christoph Tausch, Yves Harder, Frank Zimmermann, Fabienne D. Schwab, Veronica D’Amico, Savas D. Soysal, Liliana Castrezana López, Ilario Fulco, Lars G. Hemkens, Visnu Lohsiriwat, Bahadır M. Güllüoğlu, Güldeniz Karadeniz, Hasan Karanlık, Atakan Sezer, Mehmet Ali Gülçelik, Mustafa Emiroğlu, Tibor Kovács, Tim Rattay, Laszlo Romics, Raghavan Vidya, Lynda Wyld, Mahmoud El‐Tamer, Virgilio Sacchini - The Lancet Oncology 2020 cited by 62
- ErbB Receptor-induced Activation of Stat Transcription Factors Is Mediated by Src Tyrosine Kinases
Authors: Monilola A. Olayioye, Iwan Beuvink, K Horsch, J.M. Daly, Nancy E. Hynes - Journal of Biological Chemistry 1999 cited by 366
- Single-Chain Antibody-Mediated Intracellular Retention of ErbB-2 Impairs Neu Differentiation Factor and Epidermal Growth Factor Signaling
Authors: Diana Graus-Porta, Roger R. Beerli, Nancy E. Hynes - Molecular and Cellular Biology 1995 cited by 298
- Autocrine WNT signaling contributes to breast cancer cell proliferation via the canonical WNT pathway and EGFR transactivation
Authors: Thomas Schlange, Yutaka Matsuda, Susanne Lienhard, Alexandre Huber, Nancy E. Hynes - Breast Cancer Research 2007 cited by 229
- FGF receptors control vitamin D and phosphate homeostasis by mediating renal FGF-23 signaling and regulating FGF-23 expression in bone
Authors: Simon Wöhrle, Olivier Bonny, Noémie Beluch, Swann Gaulis, Christelle Stamm, Marcel Scheibler, Mathias Müller, Bernd Kinzel, Anne Thuery, Joseph Brueggen, Nancy E. Hynes, William R. Sellers, Francesco Hofmann, Diana Graus-Porta - Journal of Bone and Mineral Research 2011 cited by 147
- The ErbB receptor tyrosine family as signal integrators.
Authors: Nancy E. Hynes, K Horsch, Monilola A. Olayioye, Ali Badache - Endocrine Related Cancer 2001 cited by 140
- Monoclonal antibodies against the extracellular domain of the erbB-2 receptor function as partial ligand agonists.
Authors: Ina Maria Harwerth, Winfried S. Wels, Barbara Marte, Nancy E. Hynes - Journal of Biological Chemistry 1992 cited by 122
