Neil Aronin
Active 1981–2025
- Also published as
- NEIL ARONIN
- 90
- Papers
- 21,598
- Citations
- 74
- h-index
- 86
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Biochemistry, Genetics and Molecular Biology48.2%
- Neuroscience33%
- Medicine14.8%
- Agricultural and Biological Sciences1.7%
- Immunology and Microbiology1%
- Engineering0.4%
- Other0.9%
Topics
- Genetic Neurodegenerative Diseases8.9%
- MicroRNA in disease regulation6.8%
- RNA Interference and Gene Delivery6.2%
- Mitochondrial Function and Pathology6%
- Extracellular vesicles in disease6%
- Neurological disorders and treatments2.8%
- Other63.3%
Coauthors
- Marian DiFiglia60
- Ellen Sapp45
- Anastasia Khvorova22
- Kathryn Chase19
- Dimas Echeverria16
- Julia F. Alterman14
- Rachael Miller14
- Kimberly B. Kegel13
- Andrew H. Coles11
- Matthew Hassler11
- Reka A. Haraszti11
- Bruno M.D.C. Godinho10
- Edith L. Pfister7
- Ken Yamada7
- Marie-Cécile Didiot7
- Miguel Sena‐Esteves7
- Xueyi Li7
- Zheng‐Hong Qin7
- Heather Gray‐Edwards6
- J. Steven Alexander6
- Phillip D. Zamore6
- Antonio Valencia5
- Ashley Summers5
- Brianna Bramato5
All papers
- Exosomes Produced from 3D Cultures of MSCs by Tangential Flow Filtration Show Higher Yield and Improved Activity
Authors: Reka A. Haraszti, Rachael Miller, Matteo Stoppato, Yves Y. Sere, Andrew H. Coles, Marie-Cécile Didiot, Rachel Wollacott, Ellen Sapp, Michelle L. Dubuke, Xuni Li, Scott A. Shaffer, Marian DiFiglia, Yang Wang, Neil Aronin, Anastasia Khvorova - Molecular Therapy 2018 cited by 563
- High‐resolution proteomic and lipidomic analysis of exosomes and microvesicles from different cell sources
Authors: Reka A. Haraszti, Marie-Cécile Didiot, Ellen Sapp, John Leszyk, Scott A. Shaffer, Hannah E. Rockwell, Fei Gao, Niven R. Narain, Marian DiFiglia, Michael A. Kiebish, Neil Aronin, Anastasia Khvorova - Journal of Extracellular Vesicles 2016 cited by 745
- Exosome-mediated Delivery of Hydrophobically Modified siRNA for Huntingtin mRNA Silencing
Authors: Marie-Cécile Didiot, Lauren M Hall, Andrew H. Coles, Reka A. Haraszti, Bruno M.D.C. Godinho, Kathryn Chase, Ellen Sapp, Socheata Ly, Julia F. Alterman, Matthew Hassler, Dimas Echeverria, Lakshmi Raj, David V Morrissey, Marian DiFiglia, Neil Aronin, Anastasia Khvorova - Molecular Therapy 2016 cited by 474
- Aggregation of Huntingtin in Neuronal Intranuclear Inclusions and Dystrophic Neurites in Brain
Authors: Marian DiFiglia, Ellen Sapp, Kathryn Chase, Stephen W. Davies, Gillian P. Bates, J.-P. G. Vonsattel, Neil Aronin - Science 1997 cited by 2,922
- A divalent siRNA chemical scaffold for potent and sustained modulation of gene expression throughout the central nervous system
Authors: Julia F. Alterman, Bruno M.D.C. Godinho, Matthew Hassler, Chantal Ferguson, Dimas Echeverria, Ellen Sapp, Reka A. Haraszti, Andrew H. Coles, Faith Conroy, Rachael Miller, Loïc Roux, Paul Yan, Emily G. Knox, Anton A. Turanov, R King, Gwladys Gernoux, Christian Mueller, Heather Gray‐Edwards, Richard P. Moser, Nina Bishop, Samer M. Jaber, Matthew J. Gounis, Miguel Sena‐Esteves, Athma A. Pai, Marian DiFiglia, Neil Aronin, Anastasia Khvorova - Nature Biotechnology 2019 cited by 229
- Asymmetry in the Assembly of the RNAi Enzyme Complex
Authors: Dianne S. Schwarz, György Hutvágner, Tingting Du, Zuoshang Xu, Neil Aronin, Phillip D. Zamore - Cell 2003 cited by 2,810
- Early and Progressive Accumulation of Reactive Microglia in the Huntington Disease Brain
Authors: Ellen Sapp, Kimberly B. Kegel, Neil Aronin, Tsutomu Hashikawa, Yasuo Uchiyama, Koujiro Tohyama, Pradeep G. Bhide, J.-P. G. Vonsattel, Marian DiFiglia - Journal of Neuropathology & Experimental Neurology 2001 cited by 540
- Comparison of partially and fully chemically-modified siRNA in conjugate-mediated delivery in vivo
Authors: Matthew Hassler, Anton A. Turanov, Julia F. Alterman, Reka A. Haraszti, Andrew H. Coles, Maire F. Osborn, Dimas Echeverria, Mehran Nikan, William E. Salomon, Loïc Roux, Bruno M.D.C. Godinho, Sarah M. Davis, David V Morrissey, Phillip D. Zamore, S. Ananth Karumanchi, Melissa J. Moore, Neil Aronin, Anastasia Khvorova - Nucleic Acids Research 2018 cited by 180
- The Extracellular RNA Communication Consortium: Establishing Foundational Knowledge and Technologies for Extracellular RNA Research
Authors: Saumya Das, Asim B. Abdel‐Mageed, Catherine Adamidi, P. David Adelson, Kemal M. Akat, Eric Alsop, K. Mark Ansel, Jorge Arango, Neil Aronin, Seda Kilinc Avsaroglu, Azadeh Azizian, Leonora Balaj, Iddo Z. Ben‐Dov, Karl Bertram, Markus Bitzer, Robert Blelloch, Kimberly A. Bogardus, Xandra O. Breakefield, George A. Călin, Bob S. Carter, Al Charest, Clark C. Chen, Tanuja Chitnis, Robert J. Coffey, Amanda Courtright-Lim, Saumya Das, Amrita Datta, Peter DeHoff, Thomas G. Diacovo, David J. Erle, Alton Etheridge, Marc Ferrer, Jeffrey L. Franklin, Jane E. Freedman, David J. Galas, Timur R. Galeev, Roopali Gandhi, Aitor Garcia, Mark Gerstein, Vikas Ghai, Ionita Ghiran, María D. Giraldez, Andrei Goga, Tasos Gogakos, Béatrice Goilav, Stephen J. Gould, Peixuan Guo, Mihir Gupta, Fred H. Hochberg, Bo Huang, Matt Huentelman, Craig P. Hunter, Elizabeth Hutchins, Andrew R. Jackson, M. Yashar S. Kalani, Pınar Kanlikilicer, Reka Agnes Karaszti, Kendall Van Keuren-Jensen, Anastasia Khvorova, Yong Kim, Hogyoung Kim, Taek‐Kyun Kim, Robert R. Kitchen, Richard P. Kraig, Anna M. Krichevsky, Raymond Y. Kwong, Louise C. Laurent, Min Young Lee, Noëlle D. L’Étoile, Shawn Levy, Feng Li, Jenny Li, Xin Li, Gabriel Lopez‐Berestein, Rocco Lucero, Bogdan Mateescu, A. Matin, Klaas E.A. Max, Michael T. McManus, Thorsten R. Mempel, Cindy Meyer, Aleksandar Milosavljevic, Debasis Mondal, Kenneth J. Mukamal, Oscar Murillo, Thangamani Muthukumar, Deborah A. Nickerson, Christopher J. O’Donnell, Dinshaw J. Patel, Tushar Patel, James G. Patton, Anu Paul, Elaine R. Peskind, Mitch A. Phelps, Chaim Putterman, Peter J. Quesenberry, Joseph F. Quinn, Robert L. Raffai, Saritha Ranabothu, Shannon Jiang Rao and 57 more - Cell 2019 cited by 230
- Di-valent siRNA-mediated silencing of MSH3 blocks somatic repeat expansion in mouse models of Huntington’s disease
Authors: Daniel O’Reilly, Jillian Belgrad, Chantal Ferguson, Ashley Summers, Ellen Sapp, Cassandra McHugh, Ella Mathews, Adel Boudi, Julianna Buchwald, Socheata Ly, Dimas Echeverria, Raymond Furgal, Eric Luu, Zachary Kennedy, Vignesh Hariharan, Kathryn Monopoli, X William Yang, J. A. Carroll, Marian DiFiglia, Neil Aronin, Anastasia Khvorova - Molecular Therapy 2023 cited by 54
- HTT-lowering reverses Huntington’s disease immune dysfunction caused by NFκB pathway dysregulation
Authors: Ulrike Träger, Ralph André, Nayana Lahiri, Anna Magnusson-Lind, Andreas Weiss, Stephan Grueninger, Chris McKinnon, Eva C. Sirinathsinghji, Shira Kahlon, Edith L. Pfister, Roger Moser, Holger Hummerich, Michael Antoniou, Gillian P. Bates, Ruth Luthi‐Carter, Mark W. Lowdell, Maria Björkqvist, Gary R. Ostroff, Neil Aronin, Sarah J. Tabrizi - Brain 2014 cited by 189
- A Safe and Reliable Technique for CNS Delivery of AAV Vectors in the Cisterna Magna
Authors: Toloo Taghian, Miklós Marosföi, Ajit S Puri, Oğuz Çataltepe, R King, Elise B. Diffie, Anne S. Maguire, Douglas R. Martin, Deborah Fernau, Ana Rita Batista, Tim Kuchel, Chris Christou, Raj Perumal, Sundeep Chandra, Paul D. Gamlin, Stephanie Bertrand, Terence R. Flotte, Diane McKenna‐Yasek, Phillip W.L. Tai, Neil Aronin, Matthew J. Gounis, Miguel Sena‐Esteves, Heather Gray‐Edwards - Molecular Therapy 2019 cited by 106
- Serum Deprivation of Mesenchymal Stem Cells Improves Exosome Activity and Alters Lipid and Protein Composition
Authors: Reka A. Haraszti, Rachael Miller, Michelle L. Dubuke, Hannah E. Rockwell, Andrew H. Coles, Ellen Sapp, Marie-Cécile Didiot, Dimas Echeverria, Matteo Stoppato, Yves Y. Sere, John Leszyk, Julia F. Alterman, Bruno M.D.C. Godinho, Matthew Hassler, Justice McDaniel, Niven R. Narain, Rachel Wollacott, Yang Wang, Scott A. Shaffer, Michael A. Kiebish, Marian DiFiglia, Neil Aronin, Anastasia Khvorova - iScience 2019 cited by 102
- Chemical engineering of therapeutic siRNAs for allele-specific gene silencing in Huntington’s disease models
Authors: Faith Conroy, Rachael Miller, Julia F. Alterman, Matthew Hassler, Dimas Echeverria, Bruno M.D.C. Godinho, Emily G. Knox, Ellen Sapp, Jaquelyn Sousa, Ken Yamada, Farah Mahmood, Adel Boudi, Kimberly B. Kegel-Gleason, Marian DiFiglia, Neil Aronin, Anastasia Khvorova, Edith L. Pfister - Nature Communications 2022 cited by 48
- Huntingtin Expression Stimulates Endosomal–Lysosomal Activity, Endosome Tubulation, and Autophagy
Authors: Kimberly B. Kegel, Manho Kim, Ellen Sapp, Charmian McIntyre, José G. Castaño, Neil Aronin, Marian DiFiglia - Journal of Neuroscience 2000 cited by 543
- Hydrophobically Modified siRNAs Silence Huntingtin mRNA in Primary Neurons and Mouse Brain
Authors: Julia F. Alterman, Lauren M Hall, Andrew H. Coles, Matthew Hassler, Marie-Cécile Didiot, Kathryn Chase, Jasmin Abraham, Emily Sottosanti, Emily Johnson, Ellen Sapp, Maire F. Osborn, Marian DiFiglia, Neil Aronin, Anastasia Khvorova - Molecular Therapy — Nucleic Acids 2015 cited by 165
- 5΄-Vinylphosphonate improves tissue accumulation and efficacy of conjugated siRNAs in vivo
Authors: Reka A. Haraszti, Loïc Roux, Andrew H. Coles, Anton A. Turanov, Julia F. Alterman, Dimas Echeverria, Bruno M.D.C. Godinho, Neil Aronin, Anastasia Khvorova - Nucleic Acids Research 2017 cited by 124
- Comparative route of administration studies using therapeutic siRNAs show widespread gene modulation in Dorset sheep
Authors: Chantal Ferguson, Bruno M.D.C. Godinho, Julia F. Alterman, Andrew H. Coles, Matthew Hassler, Dimas Echeverria, James W. Gilbert, Emily G. Knox, Jillian Caiazzi, Reka A. Haraszti, R King, Toloo Taghian, Ajit S Puri, Richard P. Moser, Matthew J. Gounis, Neil Aronin, Heather Gray‐Edwards, Anastasia Khvorova - JCI Insight 2021 cited by 29
- Huntingtin is a cytoplasmic protein associated with vesicles in human and rat brain neurons
Authors: Marian DiFiglia, Ellen Sapp, Kathryn Chase, Cordula Schwarz, Alison R. Meloni, Christine Young, Eileen J. Martin, Jean‐Paul Vonsattel, Robert E. Carraway, Steven A. Reeves, Frederick M. Boyce, Neil Aronin - Neuron 1995 cited by 743
- Ly6a Differential Expression in Blood–Brain Barrier Is Responsible for Strain Specific Central Nervous System Transduction Profile of AAV-PHP.B
Authors: Ana Rita Batista, Oliver D. King, Christopher Reardon, Crystal Davis, Shankaracharya, Vivek M. Philip, Heather Gray‐Edwards, Neil Aronin, Cathleen Lutz, John E. Landers, Miguel Sena‐Esteves - Human Gene Therapy 2019 cited by 106
- Optimized Cholesterol-siRNA Chemistry Improves Productive Loading onto Extracellular Vesicles
Authors: Reka A. Haraszti, Rachael Miller, Marie-Cécile Didiot, Annabelle Biscans, Julia F. Alterman, Matthew Hassler, Loïc Roux, Dimas Echeverria, Ellen Sapp, Marian DiFiglia, Neil Aronin, Anastasia Khvorova - Molecular Therapy 2018 cited by 102
- Enhancing siRNA efficacy in vivo with extended nucleic acid backbones
Authors: Ken Yamada, Vignesh Hariharan, Jillian Caiazzi, Rachael Miller, Chantal Ferguson, Ellen Sapp, Hassan H. Fakih, Qi Tang, Nozomi Yamada, Raymond Furgal, Joseph Paquette, Annabelle Biscans, Brianna Bramato, Nicholas McHugh, Ashley Summers, Clemens Lochmann, Bruno M.D.C. Godinho, Samuel Hildebrand, S Jackson, Dimas Echeverria, Matthew Hassler, Julia F. Alterman, Marian DiFiglia, Neil Aronin, Anastasia Khvorova - Nature Biotechnology 2024 cited by 43
- CRISPRseek: A Bioconductor Package to Identify Target-Specific Guide RNAs for CRISPR-Cas9 Genome-Editing Systems
Authors: Lihua Julie Zhu, Benjamin Holmes, Neil Aronin, Michael H. Brodsky - PLoS ONE 2014 cited by 200
- Mutant huntingtin messenger RNA forms neuronal nuclear clusters in rodent and human brains
Authors: Socheata Ly, Marie-Cécile Didiot, Chantal Ferguson, Andrew H. Coles, Rachael Miller, Kathryn Chase, Dimas Echeverria, Feng Wang, Ghazaleh Sadri‐Vakili, Neil Aronin, Anastasia Khvorova - Brain Communications 2022 cited by 34
