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Nicholas J. Ashton

Active 1949–2026

Also published as
Nicholas J Ashton
342
Papers
29,660
Citations
92
h-index
306
i10-index

Citations

Citations per year for Nicholas J. Ashton1967: 4 citations1968: 5 citations1969: 5 citations1970: 10 citations1971: 5 citations1972: 4 citations1973: 1 citations1974: 10 citations1975: 7 citations1976: 5 citations1977: 13 citations1978: 12 citations1979: 7 citations1980: 10 citations1981: 7 citations1982: 13 citations1983: 11 citations1984: 9 citations1985: 18 citations1986: 3 citations1987: 3 citations1988: 11 citations1989: 6 citations1990: 9 citations1991: 10 citations1992: 10 citations1993: 13 citations1994: 11 citations1995: 6 citations1996: 10 citations1997: 8 citations1998: 5 citations1999: 7 citations2000: 8 citations2001: 9 citations2002: 8 citations2003: 8 citations2004: 3 citations2005: 8 citations2006: 8 citations2007: 11 citations2008: 6 citations2009: 7 citations2010: 15 citations2011: 7 citations2012: 11 citations2013: 15 citations2014: 10 citations2015: 11 citations2016: 15 citations2017: 11 citations2018: 15 citations2019: 86 citations2020: 453 citations2021: 1,104 citations2022: 1,826 citations2023: 2,117 citations2024: 3,868 citations2025: 2,792 citations2026: 112 citations

Citation sources

Countries

World map of the countries and regions citing this authorUnited States: 2,412 citing papers, 21.2% of this breakdownUnited Kingdom: 1,163 citing papers, 10.2% of this breakdownSweden: 928 citing papers, 8.2% of this breakdownChina: 919 citing papers, 8.1% of this breakdownGermany: 515 citing papers, 4.5% of this breakdownItaly: 500 citing papers, 4.4% of this breakdownCanada: 411 citing papers, 3.6% of this breakdownSpain: 400 citing papers, 3.5% of this breakdownFrance: 379 citing papers, 3.3% of this breakdownNetherlands: 373 citing papers, 3.3% of this breakdownAustralia: 266 citing papers, 2.4% of this breakdownSwitzerland: 266 citing papers, 2.3% of this breakdown
0%21.2%Other 25%

Institutions

Fields

  • Medicine70.9%
  • Neuroscience11.5%
  • Biochemistry, Genetics and Molecular Biology11.5%
  • Immunology and Microbiology1.4%
  • Engineering1.1%
  • Chemistry0.6%
  • Other3%

Topics

  • Alzheimer's disease research and treatments15.2%
  • Dementia and Cognitive Impairment Research11.2%
  • Neuroinflammation and Neurodegeneration Mechanisms4.3%
  • Long-Term Effects of COVID-193.1%
  • Tryptophan and brain disorders1.8%
  • Parkinson's Disease Mechanisms and Treatments1.8%
  • Other62.6%

Coauthors

All papers

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  1. Blood phosphorylated tau 181 as a biomarker for Alzheimer's disease: a diagnostic performance and prediction modelling study using data from four prospective cohorts

    Authors: Thomas K. Karikari, Tharick A. Pascoal, Nicholas J. Ashton, Shorena Janelidze, Andréa Lessa Benedet, Juan Lantero‐Rodriguez, Mira Chamoun, Mélissa Savard, Min Su Kang, Joseph Therriault, Michael Schöll, Gassan Massarweh, Jean-Paul Soucy, Kina Höglund, Gunnar Brinkmalm, Niklas Mattsson, Sebastian Palmqvist, Serge Gauthier, Erik Stomrud, Henrik Zetterberg, Oskar Hansson, Pedro Rosa‐Neto, Kaj Blennow - The Lancet Neurology 2020 cited by 1,360

  2. Diagnostic Accuracy of a Plasma Phosphorylated Tau 217 Immunoassay for Alzheimer Disease Pathology

    Authors: Nicholas J. Ashton, Wagner S. Brum, Guglielmo Di Molfetta, Andréa Lessa Benedet, Burak Arslan, Erin M. Jonaitis, Rebecca E. Langhough, Karly Alex Cody, Rachael E. Wilson, Cynthia M. Carlsson, Eugeen Vanmechelen, Laia Montoliu‐Gaya, Juan Lantero‐Rodriguez, Nesrine Rahmouni, Cécile Tissot, Jenna Stevenson, Stijn Servaes, Joseph Therriault, Tharick A. Pascoal, Alberto Lleó, Daniel Alcolea, Juan Fortea, Pedro Rosa‐Neto, Sterling C. Johnson, Andreas Jeromin, Kaj Blennow, Henrik Zetterberg - JAMA Neurology 2024 cited by 768

  3. Head-to-head comparison of 10 plasma phospho-tau assays in prodromal Alzheimer’s disease

    Authors: Shorena Janelidze, Divya Bali, Nicholas J. Ashton, Nicolas R. Barthélemy, Jeroen Vanbrabant, Erik Stoops, Eugeen Vanmechelen, Yingxin He, Anna Orduña Dolado, Gallen Triana‐Baltzer, Michael J. Pontecorvo, Henrik Zetterberg, Hartmuth C. Kolb, Manu Vandijck, Kaj Blennow, Randall J. Bateman, Oskar Hansson - Brain 2022 cited by 505

  4. Differences Between Plasma and Cerebrospinal Fluid Glial Fibrillary Acidic Protein Levels Across the Alzheimer Disease Continuum

    Authors: Andréa Lessa Benedet, Marta Milà‐Alomà, Agathe Vrillon, Nicholas J. Ashton, Tharick A. Pascoal, Firoza Z Lussier, Thomas K. Karikari, Claire Hourrègue, Emmanuel Cognat, Julien Dumurgier, Jenna Stevenson, Nesrine Rahmouni, Vanessa Pallen, Nina Margherita Poltronetti, Gemma Salvadó, Mahnaz Shekari, Grégory Operto, Juan Domingo Gispert, Carolina Minguillón, Karine Fauria, Gwendlyn Kollmorgen, Ivonne Suridjan, Eduardo R. Zimmer, Henrik Zetterberg, José Luís Molinuevo, Claire Paquet, Pedro Rosa‐Neto, Kaj Blennow, Marc Suárez‐Calvet, Translational Biomarkers in Aging and Dementia (TRIAD) study, Alzheimer’s and Families (ALFA) study, and BioCogBank Paris Lariboisière cohort, Annabella Beteta, Raffaele Cacciaglia, Alba Cañas, Carme Deulofeu, Irene Cumplido, Ruth Dominguez, Maria Emilio, Carles Falcón, Sherezade Fuentes, Laura L. Hernandez, Gema Huesa, Jordi Huguet, Paula Marne, Tania Menchón, Grégory Operto, Albina Polo, Sandra Pradas, Anna Soteras, Marc Vilanova, Natàlia Vilor‐Tejedor, Sinead Gaubert, Matthieu Lilamand, Jacques Hugon, Sandrine Indart, Alexandra Fayel, Malika Gmiz, Hélène Francisque, Aurélie Méauzoone, Matthieu Martinet, Gabrielle Tence, Mira Chamoun, Joseph Therriault, Cécile Tissot, Gleb Bezgin, Serge Gauthier, Guilaine Gagnon, Alyssa Stevensson - JAMA Neurology 2021 cited by 631

  5. Differential roles of Aβ42/40, p-tau231 and p-tau217 for Alzheimer’s trial selection and disease monitoring

    Authors: Nicholas J. Ashton, Shorena Janelidze, Niklas Mattsson, Alexa Pichet Binette, Olof Strandberg, Wagner S. Brum, Thomas K. Karikari, Fernando González‐Ortiz, Guglielmo Di Molfetta, Francisco J. Meda, Erin M. Jonaitis, Rebecca L. Koscik, Karly Alex Cody, Tobey J. Betthauser, Yan Li, Eugeen Vanmechelen, Sebastian Palmqvist, Erik Stomrud, Randall J. Bateman, Henrik Zetterberg, Sterling C. Johnson, Kaj Blennow, Oskar Hansson - Nature Medicine 2022 cited by 431

  6. Plasma p-tau231: a new biomarker for incipient Alzheimer’s disease pathology

    Authors: Nicholas J. Ashton, Tharick A. Pascoal, Thomas K. Karikari, Andréa L. Benedet, Juan Lantero‐Rodriguez, Gunnar Brinkmalm, Anniina Snellman, Michael Schöll, Claire Troakes, Abdul Hye, Serge Gauthier, Eugeen Vanmechelen, Henrik Zetterberg, Pedro Rosa‐Neto, Kaj Blennow - Acta Neuropathologica 2021 cited by 719

  7. Plasma GFAP is an early marker of amyloid-β but not tau pathology in Alzheimer’s disease

    Authors: Joana B Pereira, Shorena Janelidze, Ruben Smith, Niklas Mattsson, Sebastian Palmqvist, Charlotte E. Teunissen, Henrik Zetterberg, Erik Stomrud, Nicholas J. Ashton, Kaj Blennow, Oskar Hansson - Brain 2021 cited by 587

  8. Plasma p-tau231 and p-tau217 as state markers of amyloid-β pathology in preclinical Alzheimer’s disease

    Authors: Marta Milà‐Alomà, Nicholas J. Ashton, Mahnaz Shekari, Gemma Salvadó, Paula Ortiz‐Romero, Laia Montoliu‐Gaya, Andréa Lessa Benedet, Thomas K. Karikari, Juan Lantero‐Rodriguez, Eugeen Vanmechelen, Theresa A. Day, Armand González‐Escalante, Gonzalo Sánchez‐Benavides, Carolina Minguillón, Karine Fauria, José Luís Molinuevo, Jeffrey L. Dage, Henrik Zetterberg, Juan Domingo Gispert, Marc Suárez‐Calvet, Kaj Blennow - Nature Medicine 2022 cited by 349

  9. A multicentre validation study of the diagnostic value of plasma neurofilament light

    Authors: Nicholas J. Ashton, Shorena Janelidze, Ahmad Al Khleifat, Antoine Leuzy, Emma L. van der Ende, Thomas K. Karikari, Andréa Lessa Benedet, Tharick A. Pascoal, Alberto Lleó, Lucilla Parnetti, Daniela Galimberti, Laura Bonanni, Andrea Pilotto, Alessandro Padovani, Jan Lycke, Lenka Novakova, Markus Axelsson, Latha Velayudhan, Gil D. Rabinovici, Bruce L. Miller, Carmine M. Pariante, Naghmeh Nikkheslat, Susan M. Resnick, Madhav Thambisetty, Michael Schöll, Gorka Fernández‐Eulate, Francisco J. Gil‐Bea, Adolfo López de Munaín, Ammar Al‐Chalabi, Pedro Rosa‐Neto, André Strydom, Per Svenningsson, Erik Stomrud, Alexander Santillo, Dag Aarsland, John C. van Swieten, Sebastian Palmqvist, Henrik Zetterberg, Kaj Blennow, Abdul Hye, Oskar Hansson - Nature Communications 2021 cited by 555

  10. Astrocyte reactivity influences amyloid-β effects on tau pathology in preclinical Alzheimer’s disease

    Authors: Bruna Bellaver, Guilherme Povala, Pâmela C.L. Ferreira, João Pedro Ferrari‐Souza, Douglas Teixeira Leffa, Firoza Z Lussier, Andréa Lessa Benedet, Nicholas J. Ashton, Gallen Triana‐Baltzer, Hartmuth C. Kolb, Cécile Tissot, Joseph Therriault, Stijn Servaes, Jenna Stevenson, Nesrine Rahmouni, Oscar L. López, Dana Tudorascu, Victor L. Villemagne, Miloš D. Ikonomović, Serge Gauthier, Eduardo R. Zimmer, Henrik Zetterberg, Kaj Blennow, Howard Aizenstein, William E. Klunk, Beth E. Snitz, Pauline M. Maki, Rebecca C. Thurston, Ann D. Cohen, Mary Ganguli, Thomas K. Karikari, Pedro Rosa‐Neto, Tharick A. Pascoal - Nature Medicine 2023 cited by 310

  11. Prediction of Longitudinal Cognitive Decline in Preclinical Alzheimer Disease Using Plasma Biomarkers

    Authors: Niklas Mattsson, Gemma Salvadó, Nicholas J. Ashton, Pontus Tideman, Erik Stomrud, Henrik Zetterberg, Rik Ossenkoppele, Tobey J. Betthauser, Karly Alex Cody, Erin M. Jonaitis, Rebecca Langhough, Sebastian Palmqvist, Kaj Blennow, Shorena Janelidze, Sterling C. Johnson, Oskar Hansson - JAMA Neurology 2023 cited by 295

  12. Microglial activation and tau propagate jointly across Braak stages

    Authors: Tharick A. Pascoal, Andréa Lessa Benedet, Nicholas J. Ashton, Min Su Kang, Joseph Therriault, Mira Chamoun, Mélissa Savard, Firoza Z Lussier, Cécile Tissot, Thomas K. Karikari, Julie Ottoy, Sulantha Mathotaarachchi, Jenna Stevenson, Gassan Massarweh, Michael Schöll, Mony J. de Leon, Jean‐Paul Soucy, Paul Edison, Kaj Blennow, Henrik Zetterberg, Serge Gauthier, Pedro Rosa‐Neto - Nature Medicine 2021 cited by 520

  13. A two-step workflow based on plasma p-tau217 to screen for amyloid β positivity with further confirmatory testing only in uncertain cases

    Authors: Wagner S. Brum, Nicholas Cullen, Shorena Janelidze, Nicholas J. Ashton, Eduardo R. Zimmer, Joseph Therriault, Andréa Lessa Benedet, Nesrine Rahmouni, Cécile Tissot, Jenna Stevenson, Stijn Servaes, Gallen Triana‐Baltzer, Hartmuth C. Kolb, Sebastian Palmqvist, Erik Stomrud, Pedro Rosa‐Neto, Kaj Blennow, Oskar Hansson - Nature Aging 2023 cited by 241

  14. Association of Phosphorylated Tau Biomarkers With Amyloid Positron Emission Tomography vs Tau Positron Emission Tomography

    Authors: Joseph Therriault, Marie Vermeiren, Stijn Servaes, Cécile Tissot, Nicholas J. Ashton, Andréa Lessa Benedet, Thomas K. Karikari, Juan Lantero‐Rodriguez, Wagner S. Brum, Firoza Z Lussier, Gleb Bezgin, Jenna Stevenson, Nesrine Rahmouni, Peter Kunach, Yi-Ting Wang, Jaime Fernandez‐Arias, Kely Quispialaya Socualaya, Arthur C. Macedo, João Pedro Ferrari‐Souza, Pâmela C.L. Ferreira, Bruna Bellaver, Douglas Teixeira Leffa, Eduardo R. Zimmer, Paolo Vitali, Jean‐Paul Soucy, Gallen Triana‐Baltzer, Hartmuth C. Kolb, Tharick A. Pascoal, Paramita Saha‐Chaudhuri, Serge Gauthier, Henrik Zetterberg, Kaj Blennow, Pedro Rosa‐Neto - JAMA Neurology 2022 cited by 265

  15. Novel tau biomarkers phosphorylated at T181, T217 or T231 rise in the initial stages of the preclinical Alzheimer’s continuum when only subtle changes in Aβ pathology are detected

    Authors: Marc Suárez‐Calvet, Thomas K. Karikari, Nicholas J Ashton, Juan Lantero‐Rodriguez, Marta Milà‐Alomà, Juan Domingo Gispert, Gemma Salvadó, Carolina Minguillón, Karine Fauria, Mahnaz Shekari, Oriol Grau‐Rivera, Eider M. Arenaza‐Urquijo, Aleix Sala‐Vila, Gonzalo Sánchez‐Benavides, José María Gónzalez‐de‐Echávarri, Gwendlyn Kollmorgen, Erik Stoops, Eugeen Vanmechelen, Henrik Zetterberg, Kaj Blennow, José Luís Molinuevo, for the ALFA Study, Annabella Beteta, Raffaele Cacciaglia, Alba Cañas, Carme Deulofeu, Irene Cumplido, Ruth Dominguez, Maria Emilio, Carles Falcón, Sherezade Fuentes, Laura L. Hernandez, Gema Huesa, Jordi Huguet, Paula Marne, Tania Menchón, Grégory Operto, Albina Polo, Sandra Pradas, Anna Soteras, Marc Vilanova, Natàlia Vilor‐Tejedor - EMBO Molecular Medicine 2020 cited by 414

  16. Plasma and CSF biomarkers in a memory clinic: Head‐to‐head comparison of phosphorylated tau immunoassays

    Authors: Nicholas J. Ashton, Albert Puig‐Pijoan, Marta Milà‐Alomà, Aida Fernández‐Lebrero, Greta García‐Escobar, Fernando González‐Ortiz, Przemysław R. Kac, Wagner S. Brum, Andréa L. Benedet, Juan Lantero‐Rodriguez, Theresa A. Day, Jeroen Vanbrabant, Erik Stoops, Eugeen Vanmechelen, Gallen Triana‐Baltzer, Setareh Moughadam, Hartmuth C. Kolb, Paula Ortiz‐Romero, Thomas K. Karikari, Carolina Minguillón, Juan José Hernández Sánchez, Irene Navalpotro‐Gómez, Oriol Grau‐Rivera, R.M. Manero, Víctor Puente‐Periz, Rafael de la Torre, Jaume Roquer, Jeff L. Dage, Henrik Zetterberg, Kaj Blennow, Marc Suárez‐Calvet - Alzheimer s & Dementia 2022 cited by 224

  17. Blood phospho-tau in Alzheimer disease: analysis, interpretation, and clinical utility

    Authors: Thomas K. Karikari, Nicholas J. Ashton, Gunnar Brinkmalm, Wagner S. Brum, Andréa Lessa Benedet, Laia Montoliu‐Gaya, Juan Lantero‐Rodriguez, Tharick A. Pascoal, Marc Suárez‐Calvet, Pedro Rosa‐Neto, Kaj Blennow, Henrik Zetterberg - Nature Reviews Neurology 2022 cited by 336

  18. Specific associations between plasma biomarkers and postmortem amyloid plaque and tau tangle loads

    Authors: Gemma Salvadó, Rik Ossenkoppele, Nicholas J. Ashton, Thomas G. Beach, Geidy E. Serrano, Eric M. Reiman, Henrik Zetterberg, Niklas Mattsson, Shorena Janelidze, Kaj Blennow, Oskar Hansson - EMBO Molecular Medicine 2023 cited by 202

  19. Biomarker modeling of Alzheimer’s disease using PET-based Braak staging

    Authors: Joseph Therriault, Tharick A. Pascoal, Firoza Z Lussier, Cécile Tissot, Mira Chamoun, Gleb Bezgin, Stijn Servaes, Andréa Lessa Benedet, Nicholas J. Ashton, Thomas K. Karikari, Juan Lantero‐Rodriguez, Peter Kunach, Yi-Ting Wang, Jaime Fernandez‐Arias, Gassan Massarweh, Paolo Vitali, Jean‐Paul Soucy, Paramita Saha‐Chaudhuri, Kaj Blennow, Henrik Zetterberg, Serge Gauthier, Pedro Rosa‐Neto - Nature Aging 2022 cited by 304

  20. The diagnostic and prognostic capabilities of plasma biomarkers in Alzheimer's disease

    Authors: Joel Simrén, Antoine Leuzy, Thomas K. Karikari, Abdul Hye, Andréa Lessa Benedet, Juan Lantero‐Rodriguez, Niklas Mattsson, Michael Schöll, Patrizia Mecocci, Bruno Vellas, Magda Tsolaki, Iwona Kłoszewska, Hilkka Soininen, Simon Lovestone, Dag Aarsland, Oskar Hansson, Pedro Rosa‐Neto, Eric Westman, Kaj Blennow, Henrik Zetterberg, Nicholas J. Ashton - Alzheimer s & Dementia 2021 cited by 351

  21. Equivalence of plasma p‐tau217 with cerebrospinal fluid in the diagnosis of Alzheimer's disease

    Authors: Joseph Therriault, Stijn Servaes, Cécile Tissot, Nesrine Rahmouni, Nicholas J. Ashton, Andréa Lessa Benedet, Thomas K. Karikari, Arthur C. Macedo, Firoza Z Lussier, Jenna Stevenson, Yi‐Ting Wang, Jaime Fernandez‐Arias, Alyssa Stevenson, Kely Quispialaya Socualaya, Arlette Haeger, Tahnia Nazneen, Étienne Aumont, Seyyed Ali Hosseini, Soham Rej, Paolo Vitali, Gallen Triana‐Baltzer, Hartmuth C. Kolb, Jean‐Paul Soucy, Tharick A. Pascoal, Serge Gauthier, Henrik Zetterberg, Kaj Blennow, Pedro Rosa‐Neto - Alzheimer s & Dementia 2023 cited by 156

  22. Plasma p-tau181 accurately predicts Alzheimer’s disease pathology at least 8 years prior to post-mortem and improves the clinical characterisation of cognitive decline

    Authors: Juan Lantero‐Rodriguez, Thomas K. Karikari, Marc Suárez‐Calvet, Claire Troakes, Andrew King, Andreja Emeršič, Dag Aarsland, Abdul Hye, Henrik Zetterberg, Kaj Blennow, Nicholas J. Ashton - Acta Neuropathologica 2020 cited by 378

  23. Brain-derived tau: a novel blood-based biomarker for Alzheimer’s disease-type neurodegeneration

    Authors: Fernando González‐Ortiz, Michael Turton, Przemysław R. Kac, Denis S. Smirnov, Enrico Premi, Roberta Ghidoni, Luisa Benussi, Valentina Cantoni, Claudia Saraceno, Jasmine Rivolta, Nicholas J. Ashton, Barbara Borroni, Douglas Galasko, Peter Harrison, Henrik Zetterberg, Kaj Blennow, Thomas K. Karikari - Brain 2022 cited by 228

  24. Diagnostic and prognostic plasma biomarkers for preclinical Alzheimer's disease

    Authors: Pratishtha Chatterjee, Steve Pedrini, Nicholas J. Ashton, Michelle Tegg, Kathryn Goozee, Abhay Kumar Singh, Thomas K. Karikari, Joel Simrén, Eugeen Vanmechelen, Nicola J. Armstrong, Eugene Hone, Prita R. Asih, Kevin Taddei, Vincent Doré, Victor L. Villemagne, Hamid R. Sohrabi, Henrik Zetterberg, Colin L. Masters, Kaj Blennow, Ralph N. Martins - Alzheimer s & Dementia 2021 cited by 235