Nicholas W. Morrell
Active 1994–2025
- Also published as
- Nicholas, W. Morrell
- 175
- Papers
- 30,977
- Citations
- 94
- h-index
- 171
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Medicine63.6%
- Biochemistry, Genetics and Molecular Biology29.9%
- Immunology and Microbiology2.8%
- Neuroscience1.1%
- Chemistry0.6%
- Engineering0.4%
- Other1.6%
Topics
- Pulmonary Hypertension Research and Treatments14.5%
- Genetic Associations and Epidemiology2.2%
- MicroRNA in disease regulation2.1%
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis1.9%
- Cardiovascular Function and Risk Factors1.7%
- Vascular Anomalies and Treatments1.7%
- Other75.9%
Coauthors
- Paul D. Upton33
- Mark Southwood31
- Stefan Gräf28
- Richard C. Trembath26
- Martin R. Wilkins25
- Joanna Pepke‐Żaba23
- Mark Toshner22
- John Wharton21
- Lü Long21
- Marc Humbert21
- Christopher J. Rhodes19
- David G. Kiely17
- Emilia M. Swietlik16
- Rajiv D. Machado15
- Allan Lawrie14
- Luke Howard14
- Colin Church13
- Gerry Coghlan13
- Kurt R. Stenmark13
- Micheala A. Aldred12
- Paul A. Corris12
- Xudong Yang12
- Carmen Treacy11
- David Montani11
All papers
- Genomic atlas of the human plasma proteome
Authors: Benjamin B. Sun, Joseph C. Maranville, James E. Peters, David Stacey, James R. Staley, James A. Blackshaw, Stephen Burgess, Tao Jiang, Ellie Paige, Praveen Surendran, Clare Oliver-Williams, Mihir A. Kamat, Bram P. Prins, Sheri K. Wilcox, Erik S. Zimmerman, An Chi, Narinder Bansal, Sarah L. Spain, Angela M. Wood, Nicholas W. Morrell, John R. Bradley, Nebojsa Janjic, David J. Roberts, Willem H. Ouwehand, John A. Todd, Nicole Soranzo, Karsten Suhre, Dirk S. Paul, Caroline S. Fox, Robert M. Plenge, John Danesh, Heiko Runz, Adam S. Butterworth - Nature, Nat. 2018 cited by 2,468
- Whole-genome sequencing of patients with rare diseases in a national health system
Authors: Ernest Turro, William J. Astle, Karyn Mégy, Stefan Gräf, Daniel Greene, Olga Shamardina, Hana Lango Allen, Alba Sanchis‐Juan, Mattia Frontini, Chantal Thys, Jonathan Stephens, Rutendo Mapeta, Oliver S. Burren, Kate Downes, Matthias Haimel, Salih Tuna, Sri V. V. Deevi, Timothy J. Aitman, David Bennett, Paul Calleja, Keren Carss, Mark J. Caulfield, Patrick F. Chinnery, Peter Dixon, Daniel P. Gale, Roger James, Ania Koziell, Michael A. Laffan, Adam P. Levine, Eamonn R. Maher, Hugh S. Markus, Joannella Morales, Nicholas W. Morrell, Andrew Mumford, Elizabeth Ormondroyd, Stuart Rankin, Augusto Rendon, Sylvia Richardson, Irene Roberts, Noémi Roy, Moin A. Saleem, Kenneth G. C. Smith, Hannah Stark, Rhea Tan, Andreas C. Themistocleous, Adrian J. Thrasher, Hugh Watkins, Andrew R. Webster, Martin R. Wilkins, Catherine Williamson, James Whitworth, Sean Humphray, David R. Bentley, NIHR BioResource for the 100,000 Genomes Project, Stephen Abbs, Lara Abulhoul, Julian Adlard, Munaza Ahmed, Timothy J. Aitman, Hana Alachkar, David Allsup, J. P. Almeida, Philip Ancliff, Richard Antrobus, Ruth Armstrong, Gavin Arno, Sofie Ashford, William J. Astle, Anthony Attwood, Paul Aurora, Christian Babbs, Chiara Bacchelli, Tamam Bakchoul, Siddharth Banka, Tadbir K. Bariana, Julian Barwell, Joana Batista, Helen Baxendale, Phil Beales, David Bennett, David R. Bentley, Agnieszka Bierżyńska, Tina Biss, Maria Bitner‐Glindzicz, Graeme C. Black, Marta Bleda, Iulia Blesneac, Detlef Böckenhauer, Harm Jan Bogaard, Christian Bourne, Sara Boyce, John R. Bradley, Eugene Bragin, Gerome Breen, Paul Brennan, Carole Brewer, Matthew A. Brown, Andrew C. Browning, Michael J. Browning, Rachel Buchan and 412 more - Nature, Nat. 2020 cited by 582
- Elevated Levels of Inflammatory Cytokines Predict Survival in Idiopathic and Familial Pulmonary Arterial Hypertension
Authors: Elaine Soon, Alan Holmes, Carmen Treacy, Natalie Doughty, Laura Southgate, Rajiv D. Machado, Richard C. Trembath, Simon Jennings, Lucy Barker, Paul Nicklin, Christoph Walker, David C. Budd, Joanna Pepke‐Żaba, Nicholas W. Morrell - Circulation 2010 cited by 807
- Genetics and genomics of pulmonary arterial hypertension
Authors: Nicholas W. Morrell, Micheala A. Aldred, Wendy K. Chung, C. Gregory Elliott, William C. Nichols, Florent Soubrier, Richard C. Trembath, James E. Loyd - European Respiratory Journal 2018 cited by 468
- Selective enhancement of endothelial BMPR-II with BMP9 reverses pulmonary arterial hypertension
Authors: Lü Long, Mark L. Ormiston, Xudong Yang, Mark Southwood, Stefan Gräf, Rajiv D. Machado, Matthias Müeller, Bernd Kinzel, Lai Ming Yung, Janine M. Wilkinson, Stephen D. Moore, Kylie M. Drake, Micheala A. Aldred, Paul B. Yu, Paul D. Upton, Nicholas W. Morrell - Nature Medicine 2015 cited by 505
- Molecular genetic framework underlying pulmonary arterial hypertension
Authors: Laura Southgate, Rajiv D. Machado, Stefan Gräf, Nicholas W. Morrell - Nature Reviews Cardiology 2019 cited by 317
- Identification of MicroRNA-124 as a Major Regulator of Enhanced Endothelial Cell Glycolysis in Pulmonary Arterial Hypertension via PTBP1 (Polypyrimidine Tract Binding Protein) and Pyruvate Kinase M2
Authors: Paola Caruso, Benjamin J. Dunmore, Kenny Schlosser, Sandra Schoors, Claúdia C. dos Santos, Carol Perez‐Iratxeta, Jessie R. Lavoie, Hui Zhang, Lü Long, Amanda Flockton, Maria G. Frid, Paul D. Upton, Angelo D’Alessandro, Charaka Hadinnapola, Fedir N. Kiskin, Mohamad Taha, Liam A. Hurst, Mark L. Ormiston, Akiko Hata, Kurt R. Stenmark, Peter Carmeliet, Duncan J. Stewart, Nicholas W. Morrell - Circulation 2017 cited by 262
- BMPR2 mutations and survival in pulmonary arterial hypertension: an individual participant data meta-analysis
Authors: J. D. Evans, Barbara Girerd, David Montani, Xiao-Jian Wang, Nazzareno Galiè, Eric D. Austin, Greg Elliott, Koichiro Asano, Ekkehard Grünig, Yi Yan, Zhi‐Cheng Jing, Alessandra Manes, Massimiliano Palazzini, Lisa Wheeler, Ikue Nakayama, Toru Satoh, Christina A. Eichstaedt, Katrin Hinderhofer, Matthias Wolf, Erika B. Rosenzweig, Wendy K. Chung, Florent Soubrier, Gérald Simonneau, Olivier Sitbon, Stefan Gräf, Stephen Kaptoge, Emanuele Di Angelantonio, Marc Humbert, Nicholas W. Morrell - The Lancet Respiratory Medicine 2016 cited by 451
- Metabolic and Proliferative State of Vascular Adventitial Fibroblasts in Pulmonary Hypertension Is Regulated Through a MicroRNA-124/PTBP1 (Polypyrimidine Tract Binding Protein 1)/Pyruvate Kinase Muscle Axis
Authors: Hui Zhang, Daren Wang, Min Li, Lydie Plecitá‐Hlavatá, Angelo D’Alessandro, Jan Tauber, Suzette Riddle, Sushil Kumar, Amanda Flockton, B.A. McKeon, Maria G. Frid, Julie A. Reisz, Paola Caruso, Karim C. El Kasmi, Petr Ježek, Nicholas W. Morrell, Cheng‐Jun Hu, Kurt R. Stenmark - Circulation 2017 cited by 249
- BMPR2 Mutation and Metabolic Reprogramming in Pulmonary Arterial Hypertension
Authors: Iona Cuthbertson, Nicholas W. Morrell, Paola Caruso - Circulation Research 2023 cited by 112
- Cellular and molecular pathobiology of pulmonary arterial hypertension
Authors: Marc Humbert, Nicholas W. Morrell, Stephen L. Archer, Kurt R. Stenmark, Margaret R. MacLean, Iréne Lang, Brian W. Christman, Ε. Kenneth Weir, Oliver Eickelberg, Norbert F. Voelkel, Marlene Rabinovitch - Journal of the American College of Cardiology 2004 cited by 1,564
- Imatinib Mesylate as Add-on Therapy for Pulmonary Arterial Hypertension
Authors: Marius M. Hoeper, Robyn J. Barst, Robert C. Bourge, Jeremy Feldman, Adaani Frost, Nazzareno Galiè, Miguel Ángel Gómez‐Sánchez, Friedrich Grimminger, Ekkehard Grünig, Paul M. Hassoun, Nicholas W. Morrell, Andrew J. Peacock, Toru Satoh, Gérald Simonneau, Victor F. Tapson, Fernando Torres, David Lawrence, Deborah A. Quinn, Hossein-Ardeschir Ghofrani - Circulation 2013 cited by 562
- 2019 updated consensus statement on the diagnosis and treatment of pediatric pulmonary hypertension: The European Pediatric Pulmonary Vascular Disease Network (EPPVDN), endorsed by AEPC, ESPR and ISHLT
Authors: Georg Hansmann, Martin Köestenberger, Tero-Pekka Alastalo, Christian Apitz, Eric D. Austin, Damien Bonnet, Werner Budts, Michele D’Alto, Michael Α. Gatzoulis, Babar Hasan, Rainer Kozlik‐Feldmann, Raman Kumar, Astrid E. Lammers, Heiner Latus, Ina Michel‐Behnke, Oliver Miera, Nicholas W. Morrell, Guido Pieles, Daniel Quandt, Hannes Sallmon, Dietmar Schranz, Karin Tran‐Lundmark, Robert Tulloh, G. Warnecke, Håkan Wåhlander, Sven C. Weber, Peter Zartner - The Journal of Heart and Lung Transplantation 2019 cited by 432
- Germline selection shapes human mitochondrial DNA diversity
Authors: Wei Wei, Salih Tuna, Michael J. Keogh, Katherine R. Smith, Katherine R. Smith, Timothy J. Aitman, Phil L. Beales, David Bennett, Daniel P. Gale, Maria A. K. Bitner-Glindzicz, Graeme C. Black, Paul Brennan, Perry Elliott, Frances Flinter, R. Andrés Floto, Henry Houlden, Melita Irving, Ania Koziell, Eamonn R. Maher, Hugh S. Markus, Nicholas W. Morrell, William G. Newman, Irene Roberts, John A. Sayer, Kenneth G. C. Smith, Kenneth G. C. Smith, Jenny C. Taylor, Hugh Watkins, Andrew R. Webster, Andrew O.M. Wilkie, Catherine Williamson, NIHR BioResource–Rare Diseases, 100,000 Genomes Project–Rare Diseases Pilot, Sofie Ashford, Christopher J. Penkett, Kathleen Stirrups, Augusto Rendon, Willem H. Ouwehand, John R. Bradley, F. Lucy Raymond, Mark Caulfield, Ernest Turro, Patrick F. Chinnery, Aarnoud Huissoon, Abigail Crisp-Hihn, Adam Shaw, Adam J. Mead, Adam P. Levine, Adrian J. Thrasher, Agnieszka Bierżyńska, Ahamad Hassan, Ajith Kumar, Alba Sanchis‐Juan, Alex Richter, Allan Lawrie, Amy Frary, Andrea H. Németh, Andrea Olschewski, Andreas C. Themistocleous, Andrew C. Browning, Andrew Mumford, Andrew M. Schaefer, Andrew Marshall, Andrew O.M. Wilkie, Andrew Peacock, Andrew R. Harper, Andrew R. Webster, Andrew S.C. Rice, Angela Pyle, Ania Koziell, Anna M. Drazyk, Anne M. Kelly, Annette Wagner, Anthony Attwood, Anthony De Soyza, Anthony M. Vandersteen, Anthony T. Moore, Anton Vonk Noordegraaf, Anupama Rao, Archana Herwadkar, Arjan C. Houweling, Arjune Sen, Augusto Rendon, Austen Worth, Barbara Girerd, Bella Madan, Brian T. Wilson, Carmen Bugarin Diz, Carmen Treacy, Carole Brewer, Carolyn Campbell, Carolyn M. Millar, Catherine Roughley, Catherine Titterton, Catherine Williamson, Cecilia Compton, Cesare Danesino, Chantal Thys, Charaka Hadinnapola, Charu Deshpande and 305 more - Science 2019 cited by 251
- TNFα drives pulmonary arterial hypertension by suppressing the BMP type-II receptor and altering NOTCH signalling
Authors: Liam A. Hurst, Benjamin J. Dunmore, Lü Long, Alexi Crosby, Rafia S. Al‐Lamki, John Deighton, Mark Southwood, Xudong Yang, Marko Nikolić, Blanca Herrera, Gareth J. Inman, John R. Bradley, Amer A. Rana, Paul D. Upton, Nicholas W. Morrell - Nature Communications 2017 cited by 230
- Primary Pulmonary Hypertension Is Associated With Reduced Pulmonary Vascular Expression of Type II Bone Morphogenetic Protein Receptor
Authors: Carl Atkinson, Susan Stewart, Paul D. Upton, Rajiv D. Machado, Jennifer R. Thomson, Richard C. Trembath, Nicholas W. Morrell - Circulation 2002 cited by 684
- Plasma Metabolomics Implicates Modified Transfer RNAs and Altered Bioenergetics in the Outcomes of Pulmonary Arterial Hypertension
Authors: Christopher J. Rhodes, Pavandeep Ghataorhe, John Wharton, Kévin Rue-Albrecht, Charaka Hadinnapola, G.K. Watson, Marta Bleda, Matthias Haimel, Gerry Coghlan, Paul A. Corris, Luke Howard, David G. Kiely, Andrew J. Peacock, Joanna Pepke‐Żaba, Mark Toshner, Stephen J. Wort, J. Simon R. Gibbs, Allan Lawrie, Stefan Gräf, Nicholas W. Morrell, Martin R. Wilkins - Circulation 2016 cited by 217
- Single-cell RNA sequencing profiling of mouse endothelial cells in response to pulmonary arterial hypertension
Authors: Julie Rodor, Shiau-Haln Chen, Jessica P. Scanlon, João P Monteiro, Axelle Caudrillier, Sweta Sweta, Katherine Ross Stewart, Alena Shmakova, Ross Dobie, Beth E. P. Henderson, Kevin Stewart, Patrick W. F. Hadoke, Mark Southwood, Stephen D. Moore, Paul D. Upton, Nicholas W. Morrell, Ziwen Li, Stephen Y. Chan, Adam Handen, Robert Lafyatis, Laura de Rooij, Neil C. Henderson, Peter Carmeliet, Ana‐Mishel Spiroski, Mairi Brittan, Andrew H. Baker - Cardiovascular Research 2021 cited by 143
- Identification of rare sequence variation underlying heritable pulmonary arterial hypertension
Authors: Stefan Gräf, Matthias Haimel, Marta Bleda, Charaka Hadinnapola, Laura Southgate, Wei Li, Joshua Hodgson, Bin Liu, Richard M. Salmon, Mark Southwood, Rajiv D. Machado, Jennifer M. Martin, Carmen Treacy, Katherine Yates, Louise C. Daugherty, Olga Shamardina, Deborah Whitehorn, Simon Holden, Micheala A. Aldred, Harm Jan Bogaard, Colin Church, Gerry Coghlan, Robin Condliffe, Paul A. Corris, Cesare Danesino, Mélanie Eyries, Henning Gall, Stefano Ghio, Hossein-Ardeschir Ghofrani, J. Simon R. Gibbs, Barbara Girerd, Arjan C. Houweling, Luke Howard, Marc Humbert, David G. Kiely, Gábor Kovács, Robert V. MacKenzie Ross, Shahin Moledina, David Montani, Michael Newnham, Andrea Olschewski, Horst Olschewski, Andrew J. Peacock, Joanna Pepke‐Żaba, Inga Prokopenko, Christopher J. Rhodes, Laura Scelsi, Werner Seeger, Florent Soubrier, Dan F. Stein, Jay Suntharalingam, Emilia M. Swietlik, Mark Toshner, David A. van Heel, Anton Vonk Noordegraaf, Quinten Waisfisz, John Wharton, Stephen J. Wort, Willem H. Ouwehand, Nicole Soranzo, Allan Lawrie, Paul D. Upton, Martin R. Wilkins, Richard C. Trembath, Nicholas W. Morrell - Nature Communications 2018 cited by 384
- Chloroquine Prevents Progression of Experimental Pulmonary Hypertension via Inhibition of Autophagy and Lysosomal Bone Morphogenetic Protein Type II Receptor Degradation
Authors: Lü Long, Xudong Yang, Mark Southwood, Junyu Lu, Stefan J. Marciniak, Benjamin J. Dunmore, Nicholas W. Morrell - Circulation Research 2013 cited by 284
- HIF2α–arginase axis is essential for the development of pulmonary hypertension
Authors: Andrew S. Cowburn, Alexi Crosby, David Macías, Cristina Branco, Renato Colaço, Mark Southwood, Mark Toshner, Laura E. Crotty Alexander, Nicholas W. Morrell, Edwin R. Chilvers, Randall S. Johnson - National Academy of Sciences, Proceedings of the National Academy of Sciences 2016 cited by 183
- Using the Plasma Proteome for Risk Stratifying Patients with Pulmonary Arterial Hypertension
Authors: Christopher J. Rhodes, John Wharton, Emilia M. Swietlik, Lars Harbaum, Barbara Girerd, J. Gerry Coghlan, James Lordan, Colin Church, Joanna Pepke-Zaba, Mark Toshner, Stephen J. Wort, David G. Kiely, Robin Condliffe, Allan Lawrie, Stefan Gräf, David Montani, Athénaïs Boucly, Olivier Sitbon, Marc Humbert, Luke S. Howard, Nicholas W. Morrell, Martin R. Wilkins - American Journal of Respiratory and Critical Care Medicine 2021 cited by 81
- Cellular and Molecular Basis of Pulmonary Arterial Hypertension
Authors: Nicholas W. Morrell, Serge Adnot, Stephen L. Archer, Jocelyn Dupuis, Peter Lloyd Jones, Margaret R. MacLean, Ivan F. McMurtry, Kurt R. Stenmark, Patricia A. Thistlethwaite, Norbert Weißmann, Jason X.‐J. Yuan, Ε. Kenneth Weir - Journal of the American College of Cardiology 2009 cited by 812
- Inflammation, Growth Factors, and Pulmonary Vascular Remodeling
Authors: Paul M. Hassoun, Luc Mouthon, Joan Albert Barberà, Saadia Eddahibi, Sonia C. Flores, Friedrich Grimminger, Peter Lloyd Jones, Michael L. Maitland, Evangelos D. Michelakis, Nicholas W. Morrell, John H. Newman, Marlene Rabinovitch, Ralph T. Schermuly, Kurt R. Stenmark, Norbert F. Voelkel, Jason X.‐J. Yuan, Marc Humbert - Journal of the American College of Cardiology 2009 cited by 720
