Nigel M. Hooper
Active 1985–2024
- 112
- Papers
- 21,329
- Citations
- 83
- h-index
- 111
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Medicine58.4%
- Biochemistry, Genetics and Molecular Biology25.3%
- Neuroscience7.6%
- Nursing1.4%
- Computer Science1.4%
- Immunology and Microbiology1.3%
- Other4.6%
Topics
- Alzheimer's disease research and treatments9.4%
- COVID-19 Clinical Research Studies4.6%
- SARS-CoV-2 and COVID-19 Research3.7%
- Renin-Angiotensin System Studies3.5%
- Neuroinflammation and Neurodegeneration Mechanisms2.6%
- Computational Drug Discovery Methods2.4%
- Other73.8%
Coauthors
- Anthony J. Turner44
- Katherine A. B. Kellett15
- Nicole T. Watt9
- D Lambert7
- David R. Taylor7
- Edward T. Parkin7
- Garth J. S. Cooper6
- Heledd Jarosz-Griffiths6
- Jingshu Xu6
- Kate Fisher6
- Richard D. Unwin6
- Stephanie J. Church6
- Emma Vardy5
- Gillian Rice5
- Ishrut Hussain5
- Jo V. Rushworth5
- Melissa Scholefield5
- Peter J. Grant5
- Eric Karran4
- Federico Roncaroli4
- Fiona J. Warner4
- Isobel J. Whitehouse4
- Jodie L. Guy4
- Nicola J. Corbett4
All papers
- Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease
Authors: the Alzheimer's Disease Neuroimaging Initiative, Paul Hollingworth, Denise Harold, Rebecca Sims, Amy Gerrish, Jean‐Charles Lambert, Minerva M. Carrasquillo, Richard Abraham, Marian L. Hamshere, Jaspreet Singh Pahwa, Valentina Moskvina, Kimberley Dowzell, Nicola Jones, Alexandra Stretton, Charlene Thomas, Alex Richards, Dobril Ivanov, Caroline S. Widdowson, Jade Chapman, Simon Lovestone, John Powell, Petroula Proitsi, Michelle K. Lupton, Carol Brayne, David C. Rubinsztein, Michael Gill, Brian Lawlor, Aoibhinn Lynch, Kristelle Brown, Peter Passmore, David Craig, Bernadette McGuinness, Stephen Todd, Clive Holmes, David Mann, A. David Smith, Helen Beaumont, Donald Warden, Gordon Wilcock, Seth Love, Patrick G. Kehoe, Nigel M. Hooper, Emma Vardy, John Hardy, Simon Mead, Nick C. Fox, Martin N. Rossor, John Collinge, Wolfgang Maier, Frank Jessen, Eckart Rüther, Britta Schürmann, Reiner Heun, Heike Kölsch, Hendrik van den Bussche, Isabella Heuser, Johannes Kornhuber, Jens Wiltfang, Martin Dichgans, Lutz Frölich, Harald Hampel, John Gallacher, Michael Hüll, Dan Rujescu, Ina Giegling, Alison Goate, John Kauwe, Carlos Cruchaga, Petra Nowotny, John C. Morris, Kevin H. Mayo, Kristel Sleegers, Karolien Bettens, Sebastiaan Engelborghs, Peter Paul De Deyn, Christine Van Broeckhoven, Gill Livingston, Nicholas Bass, Hugh Gurling, Andrew McQuillin, Rhian Gwilliam, Panagiotis Deloukas, Ammar Al‐Chalabi, Christopher E. Shaw, Magda Tsolaki, Andrew B. Singleton, Rita Guerreiro, Thomas W. Mühleisen, Markus M. Nöthen, Susanne Moebus, Karl‐Heinz Jöckel, Norman Klopp, H‐Erich Wichmann, V. Shane Pankratz, Sigrid Botne Sando, Jan Aasly, Maria Barcikowska, Zbigniew K. Wszołek, Dennis W. Dickson, Neill R. Graff‐Radford and 73 more - Nature Genetics 2011 cited by 2,083
- A Human Homolog of Angiotensin-converting Enzyme
Authors: Sarah R. Tipnis, Nigel M. Hooper, Ralph Hyde, Eric Karran, Gary Christie, Anthony J. Turner - Journal of Biological Chemistry 2000 cited by 2,029
- Mild Cognitive Impairment: the Manchester consensus
Authors: Ross Dunne, Dag Aarsland, John T. O’Brien, Clive Ballard, Sube Banerjee, Nick C. Fox, Jeremy D. Isaacs, Benjamin R. Underwood, Richard Perry, Dennis Chan, Tom Dening, Alan Thomas, Jeffrey Schryer, Anne-Marie Jones, Alison Evans, Charles Alessi, Elizabeth Coulthard, James Pickett, Peter Elton, Roy Jones, Susan Mitchell, Nigel M. Hooper, Chris Kalafatis, J Rasmussen, Martin Helen, Jonathan M. Schott, Alistair Burns - Age and Ageing 2020 cited by 210
- Blended alginate/collagen hydrogels promote neurogenesis and neuronal maturation
Authors: Samuel R. Moxon, Nicola J. Corbett, Kate Fisher, Geoffrey Potjewyd, Marco Domingos, Nigel M. Hooper - Materials Science and Engineering C 2019 cited by 143
- Tumor Necrosis Factor-α Convertase (ADAM17) Mediates Regulated Ectodomain Shedding of the Severe-acute Respiratory Syndrome-Coronavirus (SARS-CoV) Receptor, Angiotensin-converting Enzyme-2 (ACE2)
Authors: D Lambert, Mike Yarski, Fiona J. Warner, Paul Thornhill, Edward T. Parkin, A. Ian Smith, Nigel M. Hooper, Anthony J. Turner - Journal of Biological Chemistry 2005 cited by 712
- Tau Proteolysis in the Pathogenesis of Tauopathies: Neurotoxic Fragments and Novel Biomarkers
Authors: James P. Quinn, Nicola J. Corbett, Katherine A. B. Kellett, Nigel M. Hooper - Journal of Alzheimer s Disease 2018 cited by 173
- Amyloid-β Receptors: The Good, the Bad, and the Prion Protein
Authors: Heledd Jarosz-Griffiths, Elizabeth Noble, Jo V. Rushworth, Nigel M. Hooper - Journal of Biological Chemistry 2015 cited by 268
- 3D hydrogel models of the neurovascular unit to investigate blood–brain barrier dysfunction
Authors: Geoffrey Potjewyd, Katherine A. B. Kellett, Nigel M. Hooper - Neuronal Signaling 2021 cited by 50
- Rare coding variants in the phospholipase D3 gene confer risk for Alzheimer’s disease
Authors: Carlos Cruchaga, Celeste M. Karch, Sheng Chih Jin, Bruno A. Benítez, Yefei Cai, Rita Guerreiro, Oscar Harari, Joanne Norton, John Budde, Sarah Bertelsen, Amanda T. Jeng, Breanna Cooper, Tara Skorupa, David Carrell, Denise Levitch, Simon Hsu, Jiyoon Choi, Mina Ryten, John Hardy, Mina Ryten, Daniah Trabzuni, Michael E. Weale, Adaikalavan Ramasamy, Colin Smith, Celeste Sassi, José Brás, J. Raphael Gibbs, Dena G. Hernandez, Michelle K. Lupton, John Powell, Paola Forabosco, Perry G. Ridge, Christopher Corcoran, JoAnn T. Tschanz, Maria C. Norton, Ronald G. Munger, Cameron Schmutz, Maegan Leary, F. Yesim Demirci, Mikhil Bamne, Xingbin Wang, Oscar L. López, Mary Ganguli, Christopher Medway, James Turton, Jenny Lord, Anne Braae, Imelda Barber, Kristelle Brown, Peter Passmore, David Craig, Janet Johnston, Bernadette McGuinness, Stephen Todd, Reinhard Heun, Heike Kölsch, Patrick G. Kehoe, Nigel M. Hooper, Emma Vardy, David Mann, Stuart Pickering‐Brown, Kristelle Brown, Noor Kalsheker, James Lowe, Kevin Morgan, A. David Smith, Gordon Wilcock, Donald Warden, Clive Holmes, Pau Pástor, Oswaldo Lorenzo‐Betancor, Zoran Brkanac, Erick R. Scott, Eric J. Topol, Kevin Morgan, Ekaterina Rogaeva, Andrew B. Singleton, John Hardy, M. Ilyas Kamboh, Peter St George‐Hyslop, Nigel J. Cairns, John C. Morris, John Kauwe, Alison Goate - Nature 2013 cited by 476
- Evaluation of angiotensin-converting enzyme (ACE), its homologue ACE2 and neprilysin in angiotensin peptide metabolism
Authors: Gillian Rice, Daniel A. Thomas, Peter J. Grant, Anthony J. Turner, Nigel M. Hooper - Biochemical Journal 2004 cited by 627
- Amyloid β synaptotoxicity is Wnt‐PCP dependent and blocked by fasudil
Authors: Katherine J. Sellers, Christina Elliott, Joshua Jackson, Anshua Ghosh, Elena M. Ribé, Ana I. Rojo, Heledd Jarosz-Griffiths, Iain A. Watson, Weiming Xia, Mikhail A. Semenov, Peter J. Morin, Nigel M. Hooper, Rod A. Porter, Jane E. Preston, Raya Al‐Shawi, George S. Baillie, Simon Lovestone, Antonio Cuadrado, Michael Harte, J. Paul Simons, Deepak P. Srivastava, Richard Killick - Alzheimer s & Dementia 2017 cited by 108
- Widespread Decreases in Cerebral Copper Are Common to Parkinson's Disease Dementia and Alzheimer's Disease Dementia
Authors: Melissa Scholefield, Stephanie J. Church, Jingshu Xu, Stefano Patassini, Federico Roncaroli, Nigel M. Hooper, Richard D. Unwin, Garth J. S. Cooper - Frontiers in Aging Neuroscience 2021 cited by 44
- Families of zinc metalloproteases
Authors: Nigel M. Hooper - FEBS Letters 1994 cited by 789
- Exclusively targeting β-secretase to lipid rafts by GPI-anchor addition up-regulates β-site processing of the amyloid precursor protein
Authors: Joanna M. Cordy, Ishrut Hussain, Colin Dingwall, Nigel M. Hooper, Anthony J. Turner - National Academy of Sciences, Proceedings of the National Academy of Sciences 2003 cited by 360
- Heme oxygenase-1 protects against Alzheimer’s amyloid-β1-42-induced toxicity via carbon monoxide production
Authors: Nishani T. Hettiarachchi, Mark Dallas, Moza M. Al‐Owais, Helen R. Griffiths, Nigel M. Hooper, Jason L. Scragg, John P. Boyle, Chris Peers - Cell Death and Disease 2014 cited by 93
- The emerging role of ACE2 in physiology and disease
Authors: Inge Hamming, M. E. Cooper, Bart L. Haagmans, Nigel M. Hooper, Ron Korstanje, ADME Osterhaus, Wim Timens, AJ Turner, G. Navis, Harry van Goor - The Journal of Pathology 2007 cited by 462
- A label-free electrical impedimetric biosensor for the specific detection of Alzheimer's amyloid-beta oligomers
Authors: Jo V. Rushworth, Asif Ahmed, Heledd Jarosz-Griffiths, Niall M. Pollock, Nigel M. Hooper, Paul A. Millner - Biosensors and Bioelectronics 2013 cited by 191
- Neprilysin, obesity and the metabolic syndrome
Authors: Kristina F. Standeven, K Hess, A M Carter, Gillian Rice, P A Cordell, Anthony J. Balmforth, Bing Lü, D. Scott, Anthony J. Turner, Nigel M. Hooper, Peter J. Grant - International Journal of Obesity 2010 cited by 171
- Elevation of brain glucose and polyol-pathway intermediates with accompanying brain-copper deficiency in patients with Alzheimer’s disease: metabolic basis for dementia
Authors: Jingshu Xu, Paul Begley, Stephanie J. Church, Stefano Patassini, Selina McHarg, Nina Kureishy, Katherine A. Hollywood, Henry J. Waldvogel, Hong Liu, Shaoping Zhang, Wanchang Lin, Karl Herholz, Clinton Turner, Beth J. Synek, Maurice A. Curtis, Jack Rivers‐Auty, Catherine B. Lawrence, Katherine A. B. Kellett, Nigel M. Hooper, Emma Vardy, Donghai Wu, Richard D. Unwin, Richard L. M. Faull, Andrew W. Dowsey, Garth J. S. Cooper - Scientific Reports 2016 cited by 87
- ACE2: from vasopeptidase to SARS virus receptor
Authors: Anthony J. Turner, Julian A. Hiscox, Nigel M. Hooper - Trends in Pharmacological Sciences 2004 cited by 536
- The Transcriptionally Active Amyloid Precursor Protein (APP) Intracellular Domain Is Preferentially Produced from the 695 Isoform of APP in a β-Secretase-dependent Pathway
Authors: Nikolai D. Belyaev, Katherine A. B. Kellett, Caroline S. Beckett, Natalia Z. Makova, Timothy J. Revett, Natalia N. Nalivaeva, Nigel M. Hooper, Anthony J. Turner - Journal of Biological Chemistry 2010 cited by 208
- Lipid Rafts: Linking Alzheimer′s Amyloid‐βProduction, Aggregation, and Toxicity at Neuronal Membranes
Authors: Jo V. Rushworth, Nigel M. Hooper - International Journal of Alzheimer s Disease 2010 cited by 213
- Angiotensin-converting Enzyme 2 (ACE2), But Not ACE, Is Preferentially Localized to the Apical Surface of Polarized Kidney Cells
Authors: Fiona J. Warner, Rebecca A. Lew, A. Ian Smith, D Lambert, Nigel M. Hooper, Anthony J. Turner - Journal of Biological Chemistry 2005 cited by 192
- ADAMs family members as amyloid precursor protein α‐secretases
Authors: Tobias M. J. Allinson, Edward T. Parkin, Anthony J. Turner, Nigel M. Hooper - Journal of Neuroscience Research 2003 cited by 430
