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O. Smithies

Active 1963–2002

Also published as
O Smithies
27
Papers
26,079
Citations
27
h-index
27
i10-index

Citations

Citations per year for O. Smithies1964: 2 citations1965: 8 citations1966: 3 citations1967: 4 citations1969: 4 citations1970: 1 citations1972: 4 citations1973: 3 citations1974: 6 citations1975: 12 citations1976: 10 citations1977: 25 citations1978: 19 citations1979: 14 citations1980: 10 citations1981: 12 citations1982: 8 citations1983: 5 citations1984: 16 citations1985: 19 citations1986: 45 citations1987: 55 citations1988: 106 citations1989: 219 citations1990: 356 citations1991: 447 citations1992: 567 citations1993: 543 citations1994: 500 citations1995: 465 citations1996: 392 citations1997: 421 citations1998: 437 citations1999: 411 citations2000: 398 citations2001: 312 citations2002: 295 citations2003: 283 citations2004: 233 citations2005: 210 citations2006: 195 citations2007: 125 citations2008: 124 citations2009: 131 citations2010: 122 citations2011: 100 citations2012: 82 citations2013: 75 citations2014: 73 citations2015: 57 citations2016: 38 citations2017: 57 citations2018: 41 citations2019: 146 citations2020: 110 citations2021: 130 citations2022: 68 citations2023: 54 citations2024: 79 citations2025: 22 citations1968: no citations, so this year is not shown1971: no citations, so this year is not shown

Citation sources

Countries

World map of the countries and regions citing this authorUnited States: 4,697 citing papers, 45% of this breakdownUnited Kingdom: 831 citing papers, 7.9% of this breakdownGermany: 813 citing papers, 7.8% of this breakdownFrance: 469 citing papers, 4.5% of this breakdownCanada: 351 citing papers, 3.3% of this breakdownJapan: 333 citing papers, 3.2% of this breakdownSweden: 280 citing papers, 2.7% of this breakdownAustralia: 278 citing papers, 2.6% of this breakdownSwitzerland: 247 citing papers, 2.4% of this breakdownItaly: 222 citing papers, 2.1% of this breakdownNetherlands: 217 citing papers, 2.1% of this breakdownSpain: 195 citing papers, 1.9% of this breakdown
0%45%Other 14.5%

Institutions

Fields

  • Biochemistry, Genetics and Molecular Biology45.7%
  • Medicine31.2%
  • Agricultural and Biological Sciences7.6%
  • Immunology and Microbiology7%
  • Neuroscience2.6%
  • Environmental Science2.2%
  • Other3.7%

Topics

  • RNA and protein synthesis mechanisms3.6%
  • Estrogen and related hormone effects3.2%
  • Bacterial Genetics and Biotechnology2.3%
  • Genomics and Phylogenetic Studies2.1%
  • Renin-Angiotensin System Studies1.6%
  • Nitric Oxide and Endothelin Effects1.4%
  • Other85.8%

Coauthors

All papers

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  1. Severe reduction in leukocyte adhesion and monocyte extravasation in mice deficient in CC chemokine receptor 2

    Authors: S. Griffin, N. Maeda, O. Smithies, K. Ley, S. J. Morgan, W. A. Kuziel, Tracey C. Dawson - National Academy of Sciences, Proceedings of the National Academy of Sciences 1997 cited by 700

  2. Alteration of reproductive function but not prenatal sexual development after insertional disruption of the mouse estrogen receptor gene.

    Authors: J. F. Couse, O. Smithies, K. S. Korach, T. S. Golding, J. S. Moyer, D. B. Lubahn - National Academy of Sciences, Proceedings of the National Academy of Sciences 1993 cited by 1,847

  3. Generation and reproductive phenotypes of mice lacking estrogen receptor β

    Authors: K. S. Korach, E. Enmark, J. F. Mahler, M. Sar, J. H. Krege, O. Smithies, Margaret Warner, J. F. Couse, J. B. Hodgin, J.-A. Gustafsson - National Academy of Sciences, Proceedings of the National Academy of Sciences 1998 cited by 1,697

  4. Elevated blood pressures in mice lacking endothelial nitric oxide synthase

    Authors: E. G. Shesely, W. C. Sessa, V. E. Laubach, O. Smithies, K. M. Desai, P. A. Sherman, N. Maeda, J. H. Krege, H.- S. Kim - National Academy of Sciences, Proceedings of the National Academy of Sciences 1996 cited by 904

  5. Direct evidence for the importance of endothelium-derived nitric oxide in vascular remodeling.

    Authors: R. Daniel Rudic, E G Shesely, N Maeda, O Smithies, S S Segal, W C Sessa - Journal of Clinical Investigation 1998 cited by 814

  6. The natriuretic peptide clearance receptor locally modulates the physiological effects of the natriuretic peptide system

    Authors: N. Takahashi, O. Smithies, M. Yamauchi, S. Pang, W. J. Grzesik, Naomich Matsukawa, K. N. Pandey - National Academy of Sciences, Proceedings of the National Academy of Sciences 1999 cited by 451

  7. Regulation of blood pressure by the type 1A angiotensin II receptor gene.

    Authors: N. Maeda, M. I. Oliverio, M. Ito, T. M. Coffman, P. J. Mannon, C. F. Best, O. Smithies - National Academy of Sciences, Proceedings of the National Academy of Sciences 1995 cited by 609

  8. Hypertension, cardiac hypertrophy, and sudden death in mice lacking natriuretic peptide receptor A

    Authors: R. L. Reddick, O. Smithies, J. E. Fox, R. Kim, H.-S. Kim, N. Maeda, S. L. Milgram, H. A. Rockman, P. M. Oliver, K. N. Pandey - National Academy of Sciences, Proceedings of the National Academy of Sciences 1997 cited by 565

  9. Coagulation defects and altered hemodynamic responses in mice lacking receptors for thromboxane A2.

    Authors: Dennis W. Thomas, Roslyn B. Mannon, P J Mannon, A M Latour, J.A. Oliver, Maureane Hoffman, O Smithies, Beverly H. Koller, Thomas M. Coffman - Journal of Clinical Investigation 1998 cited by 267

  10. Genetic control of blood pressure and the angiotensinogen locus.

    Authors: J. H. Krege, O. Smithies, H. S. Kim, J. C. Jennette, T. M. Coffman, C. F. Best, K. D. Kluckman, N. Maeda, J. R. Hagaman, J. B. Hodgin - National Academy of Sciences, Proceedings of the National Academy of Sciences 1995 cited by 642

  11. Germ-line transmission of a planned alteration made in a hypoxanthine phosphoribosyltransferase gene by homologous recombination in embryonic stem cells.

    Authors: Beverly H. Koller, Lora J. Hagemann, Thomas Doetschman, John R. Hagaman, Shaobai Huang, Parker Williams, N. L. First, Nobuo Maeda, O. Smithies - National Academy of Sciences, Proceedings of the National Academy of Sciences 1989 cited by 222

  12. Angiotensin-converting enzyme and male fertility

    Authors: D. A. O'Brien, J. R. Hagaman, M. Sibony, J. H. Krege, J. S. Moyer, Péter Magyar, O. Smithies, J. E. Welch, E. S. Bachman - National Academy of Sciences, Proceedings of the National Academy of Sciences 1998 cited by 336

  13. Ventricular expression of natriuretic peptides inNpr1 −/− mice with cardiac hypertrophy and fibrosis

    Authors: L. J. Ellmers, Joshua W. Knowles, H.-S. Kim, O. Smithies, N. Maeda, V. A. Cameron - American Journal of Physiology-Heart and Circulatory Physiology 2002 cited by 99

  14. A comprehensive set of sequence analysis programs for the VAX

    Authors: J. Devereux, P. Haeberli, O. Smithies - Nucleic Acids Research, Nucleic Acids Res. 1984 cited by 14,423

  15. Single-copy transgenic mice with chosen-site integration.

    Authors: Sarah K. Bronson, E. G. Plaehn, K D Kluckman, John R. Hagaman, Nobuo Maeda, O. Smithies - National Academy of Sciences, Proceedings of the National Academy of Sciences 1996 cited by 294

  16. Inactivating the beta 2-microglobulin locus in mouse embryonic stem cells by homologous recombination.

    Authors: Beverly H. Koller, O Smithies - National Academy of Sciences, Proceedings of the National Academy of Sciences 1989 cited by 214

  17. Beta 2-microglobulin-, CD8+ T-cell-deficient mice survive inoculation with high doses of vaccinia virus and exhibit altered IgG responses.

    Authors: Melanie K. Spriggs, Beverly H. Koller, Takeo Sato, Philip Morrissey, William C. Fanslow, O. Smithies, R F Voice, M B Widmer, Charlie Maliszewski - National Academy of Sciences, Proceedings of the National Academy of Sciences 1992 cited by 157

  18. Genetically increased angiotensin I-converting enzyme level and renal complications in the diabetic mouse

    Authors: M.-F. Belair, M. Marre, P. Meneton, P. Bruneval, J. H. Krege, W. Huang, N. Bouby, F. Alhenc-Gelas, D. Heudes, O. Smithies, Y. Gallois - National Academy of Sciences, Proceedings of the National Academy of Sciences 2001 cited by 149

  19. Regulatory elements in the introns of the human HPRT gene are necessary for its expression in embryonic stem cells.

    Authors: Laura Reid, Ronald G. Gregg, O. Smithies, Beverly H. Koller - National Academy of Sciences, Proceedings of the National Academy of Sciences 1990 cited by 103

  20. Quantitative procedures for use with the Edman-Begg sequenator. Partial sequences of two unusual immunoglobulin light chains, Rzf and Sac

    Authors: O. Smithies, D. M. Gibson, Ellen Fanning, Robert M. Goodfliesh, J. G. Gilman, Donald L. Ballantyne - Biochemistry 1971 cited by 679

  21. Altering Genes in Animals by Gene Targeting

    Authors: Beverly H. Koller, O. Smithies - Annual Review of Immunology 1992 cited by 221

  22. Recombinant fragment assay for gene targetting based on the polymerase chain reaction

    Authors: H.-S. Kim, O. Smithies - Nucleic Acids Research 1988 cited by 193

  23. Angiotensin II responses in AT1A receptor-deficient mice: a role for AT1B receptors in blood pressure regulation

    Authors: M. I. Oliverio, C. F. Best, H. S. Kim, William J. Arendshorst, O. Smithies, T. M. Coffman - American Journal of Physiology-Renal Physiology 1997 cited by 165

  24. Toward an animal model of cystic fibrosis: targeted interruption of exon 10 of the cystic fibrosis transmembrane regulator gene in embryonic stem cells.

    Authors: Beverly H. Koller, H S Kim, A M Latour, Kristen K. Brigman, R C Boucher, Peter Scambler, Brandon J. Wainwright, O. Smithies - National Academy of Sciences, Proceedings of the National Academy of Sciences 1991 cited by 91