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Ole Isacson

Active 1984–2025

145
Papers
28,101
Citations
101
h-index
145
i10-index

Citations

Citations per year for Ole Isacson1952: 1 citations1985: 5 citations1986: 18 citations1987: 33 citations1988: 54 citations1989: 63 citations1990: 53 citations1991: 63 citations1992: 72 citations1993: 59 citations1994: 53 citations1995: 104 citations1996: 68 citations1997: 66 citations1998: 102 citations1999: 85 citations2000: 122 citations2001: 94 citations2002: 128 citations2003: 209 citations2004: 231 citations2005: 168 citations2006: 239 citations2007: 223 citations2008: 246 citations2009: 354 citations2010: 332 citations2011: 329 citations2012: 273 citations2013: 260 citations2014: 257 citations2015: 244 citations2016: 207 citations2017: 193 citations2018: 214 citations2019: 599 citations2020: 679 citations2021: 622 citations2022: 444 citations2023: 336 citations2024: 433 citations2025: 210 citations2026: 2 citations1953–1984: no citations, so these years are not shown

Citation sources

Countries

World map of the countries and regions citing this authorUnited States: 2,907 citing papers, 32.4% of this breakdownUnited Kingdom: 728 citing papers, 8.1% of this breakdownChina: 582 citing papers, 6.5% of this breakdownGermany: 476 citing papers, 5.3% of this breakdownItaly: 414 citing papers, 4.6% of this breakdownSweden: 357 citing papers, 4% of this breakdownCanada: 341 citing papers, 3.8% of this breakdownFrance: 283 citing papers, 3.1% of this breakdownJapan: 258 citing papers, 2.9% of this breakdownSpain: 229 citing papers, 2.5% of this breakdownSouth Korea: 188 citing papers, 2.1% of this breakdownAustralia: 186 citing papers, 2.1% of this breakdown
0%32.4%Other 22.6%

Institutions

Fields

  • Medicine38.7%
  • Biochemistry, Genetics and Molecular Biology31.9%
  • Neuroscience26.2%
  • Engineering0.7%
  • Immunology and Microbiology0.6%
  • Nursing0.4%
  • Other1.5%

Topics

  • Parkinson's Disease Mechanisms and Treatments9.2%
  • Pluripotent Stem Cells Research6.4%
  • Nerve injury and regeneration5.5%
  • Neurogenesis and neuroplasticity mechanisms4.7%
  • Nuclear Receptors and Signaling3.3%
  • CRISPR and Genetic Engineering3.3%
  • Other67.6%

Coauthors

All papers

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  1. α-Synuclein–induced lysosomal dysfunction occurs through disruptions in protein trafficking in human midbrain synucleinopathy models

    Authors: Joseph R. Mazzulli, Friederike Zunke, Ole Isacson, Lorenz Studer, Dimitri Krainc - National Academy of Sciences, Proceedings of the National Academy of Sciences 2016 cited by 393

  2. Reduced sphingolipid hydrolase activities, substrate accumulation and ganglioside decline in Parkinson’s disease

    Authors: Mylene Huebecker, Elizabeth B. Moloney, Aarnoud C. van der Spoel, David A. Priestman, Ole Isacson, Penelope J. Hallett, Frances M. Platt - Molecular Neurodegeneration 2019 cited by 171

  3. Cell type-specific lipid storage changes in Parkinson’s disease patient brains are recapitulated by experimental glycolipid disturbance

    Authors: Oeystein Roed Brekk, Jonathan Roy Honey, Seungil Lee, Penelope J. Hallett, Ole Isacson - National Academy of Sciences, Proceedings of the National Academy of Sciences 2020 cited by 106

  4. Neuroinflammation mediated by IL-1β increases susceptibility of dopamine neurons to degeneration in an animal model of Parkinson's disease

    Authors: James B. Koprich, Casper Reske-Nielsen, Prabhakar Mithal, Ole Isacson - Journal of Neuroinflammation 2008 cited by 346

  5. Successful Function of Autologous iPSC-Derived Dopamine Neurons following Transplantation in a Non-Human Primate Model of Parkinson’s Disease

    Authors: Penelope J. Hallett, Michela Deleidi, Arnar Astradsson, Gaynor A. Smith, Oliver Cooper, Teresia Osborn, Maria Sundberg, Michele A. Moore, Eduardo Pérez-Torres, Anna‐Liisa Brownell, James M. Schumacher, Roger D. Spealman, Ole Isacson - Cell stem cell 2015 cited by 335

  6. Dynamic Changes in Presynaptic and Axonal Transport Proteins Combined with Striatal Neuroinflammation Precede Dopaminergic Neuronal Loss in a Rat Model of AAV α-Synucleinopathy

    Authors: Chee Yeun Chung, James B. Koprich, Hasan K. Siddiqi, Ole Isacson - Journal of Neuroscience 2009 cited by 388

  7. Progressive decline of glucocerebrosidase in aging and P arkinson's disease

    Authors: Emily M. Rocha, Gaynor A. Smith, Eric Park, Hongmei Cao, Eilish Brown, Penelope J. Hallett, Ole Isacson - Annals of Clinical and Translational Neurology 2015 cited by 214

  8. Glucocerebrosidase gene therapy prevents α-synucleinopathy of midbrain dopamine neurons

    Authors: Emily M. Rocha, Gaynor A. Smith, Eric Park, Hongmei Cao, Eilish Brown, Melissa A. Hayes, Jonathan A. Beagan, Jesse R. McLean, Sarah C. Izen, Eduardo Pérez-Torres, Penelope J. Hallett, Ole Isacson - Neurobiology of Disease 2015 cited by 162

  9. Sustained Systemic Glucocerebrosidase Inhibition Induces Brain α-Synuclein Aggregation, Microglia and Complement C1q Activation in Mice

    Authors: Emily M. Rocha, Gaynor A. Smith, Eric Park, Hongmei Cao, Anne-Renee Graham, Eilish Brown, Jesse R. McLean, Melissa A. Hayes, Jonathan A. Beagan, Sarah C. Izen, Eduardo Pérez-Torres, Penelope J. Hallett, Ole Isacson - Antioxidants and Redox Signaling 2015 cited by 153

  10. Pharmacological Rescue of Mitochondrial Deficits in iPSC-Derived Neural Cells from Patients with Familial Parkinson’s Disease

    Authors: Oliver Cooper, Hyemyung Seo, Shaida A. Andrabi, Cristina Guardia‐Laguarta, John J. Graziotto, Maria Sundberg, Jesse R. McLean, Luis Carrillo‐Reid, Zhong Xie, Teresia Osborn, Gunnar Hargus, Michela Deleidi, Tristan Lawson, Helle Bogetofte, Eduardo Pérez-Torres, Lorraine N. Clark, Carol Moskowitz, Joseph R. Mazzulli, Li Chen, Laura A. Volpicelli‐Daley, Norma B. Romero, Houbo Jiang, Ryan J. Uitti, Zhigao Huang, Grzegorz Opala, Leslie A. Scarffe, Valina L. Dawson, Christine Klein, Jian Feng, Owen A. Ross, John Q. Trojanowski, Virginia M.‐Y. Lee, Karen Marder, D. James Surmeier, Zbigniew K. Wszołek, Serge Przedborski, Dimitri Krainc, Ted M. Dawson, Ole Isacson - Science Translational Medicine 2012 cited by 506

  11. Parkinson's Disease Patient-Derived Induced Pluripotent Stem Cells Free of Viral Reprogramming Factors

    Authors: Frank Soldner, Dirk Hockemeyer, Caroline Beard, Qing Gao, George W. Bell, Elizabeth Cook, Gunnar Hargus, Alexandra Blak, Oliver Cooper, Maisam Mitalipova, Ole Isacson, Rudolf Jaenisch - Cell 2009 cited by 1,544

  12. LRRK2 mutations cause mitochondrial DNA damage in iPSC-derived neural cells from Parkinson's disease patients: Reversal by gene correction

    Authors: Laurie H. Sanders, Josée Laganière, Oliver Cooper, Sally K. Mak, B. Joseph Vu, Ying Huang, David E. Paschon, Malini Vangipuram, Ramya Sundararajan, Fyodor D. Urnov, J. William Langston, Philip D. Gregory, H. Steve Zhang, J. Timothy Greenamyre, Ole Isacson, Birgitt Schüle - Neurobiology of Disease 2013 cited by 277

  13. The glycoprotein GPNMB is selectively elevated in the substantia nigra of Parkinson's disease patients and increases after lysosomal stress

    Authors: Elizabeth B. Moloney, Alyssa Moskites, Eliza J. Ferrari, Ole Isacson, Penelope J. Hallett - Neurobiology of Disease 2018 cited by 126

  14. Integrated molecular landscape of Parkinson’s disease

    Authors: Cornelius J. H. M. Klemann, Gerard J.M. Martens, Manu Sharma, Marijn Bart Martens, Ole Isacson, Thomas Gasser, Jasper E. Visser, Geert Poelmans - npj Parkinson s Disease 2017 cited by 126

  15. Neurons derived from reprogrammed fibroblasts functionally integrate into the fetal brain and improve symptoms of rats with Parkinson's disease

    Authors: Marius Wernig, Jian-Ping Zhao, Jan Pruszak, Eva Hedlund, Dongdong Fu, Frank Soldner, Vania Broccoli, Martha Constantine‐Paton, Ole Isacson, Rudolf Jaenisch - National Academy of Sciences, Proceedings of the National Academy of Sciences 2008 cited by 1,212

  16. The Threshold Theory for Parkinson's Disease

    Authors: Simone Engelender, Ole Isacson - Trends in Neurosciences 2016 cited by 191

  17. Axon guidance and synaptic maintenance: preclinical markers for neurodegenerative disease and therapeutics

    Authors: Ling Lin, Timothy G. Lesnick, Demetrius M. Maraganore, Ole Isacson - Trends in Neurosciences 2009 cited by 167

  18. Altered Proteasomal Function in Sporadic Parkinson's Disease

    Authors: Kevin St. P. McNaught, Roger Belizaire, Ole Isacson, Peter Jenner, C. Warren Olanow - Experimental Neurology 2002 cited by 572

  19. Dopamine neurons implanted into people with Parkinson's disease survive without pathology for 14 years

    Authors: Ivar Mendez, Ángel Viñuela, Arnar Astradsson, Karim Mukhida, Penelope J. Hallett, H.A. Robertson, Travis Tierney, Renn O. Holness, Alain Dagher, John Q. Trojanowski, Ole Isacson - Nature Medicine 2008 cited by 434

  20. Cell type-specific gene expression of midbrain dopaminergic neurons reveals molecules involved in their vulnerability and protection

    Authors: Chee Yeun Chung, Hyemyung Seo, Kai‐Christian Sonntag, Andrew I. Brooks, Ling Lin, Ole Isacson - Human Molecular Genetics 2005 cited by 371

  21. Lipid and immune abnormalities causing age-dependent neurodegeneration and Parkinson’s disease

    Authors: Penelope J. Hallett, Simone Engelender, Ole Isacson - Journal of Neuroinflammation 2019 cited by 109

  22. Widespread neuron-specific transgene expression in brain and spinal cord following synapsin promoter-driven AAV9 neonatal intracerebroventricular injection

    Authors: Jesse R. McLean, Gaynor A. Smith, Emily M. Rocha, Melissa A. Hayes, Jonathan A. Beagan, Penelope J. Hallett, Ole Isacson - Neuroscience Letters 2014 cited by 109

  23. Mitochondrial clearance and maturation of autophagosomes are compromised in LRRK2 G2019S familial Parkinson’s disease patient fibroblasts

    Authors: Joanna A. Korecka, Ria Thomas, Dan Ploug Christensen, Anthony J. Hinrich, Eliza J. Ferrari, Simon A. Levy, Michelle L. Hastings, Penelope J. Hallett, Ole Isacson - Human Molecular Genetics 2019 cited by 66

  24. Differentiated Parkinson patient-derived induced pluripotent stem cells grow in the adult rodent brain and reduce motor asymmetry in Parkinsonian rats

    Authors: Gunnar Hargus, Oliver Cooper, Michela Deleidi, Adam Levy, Kristen Lee, Elizabeth Marlow, Alyssa Yow, Frank Soldner, Dirk Hockemeyer, Penelope J. Hallett, Teresia Osborn, Rudolf Jaenisch, Ole Isacson - National Academy of Sciences, Proceedings of the National Academy of Sciences 2010 cited by 473