Paul J. Thornalley
Active 1981–2025
- 151
- Papers
- 31,296
- Citations
- 99
- h-index
- 150
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Biochemistry, Genetics and Molecular Biology53.1%
- Medicine29%
- Nursing4%
- Agricultural and Biological Sciences3.2%
- Neuroscience2.5%
- Chemistry2.1%
- Other6.1%
Topics
- Advanced Glycation End Products research11%
- Natural Antidiabetic Agents Studies3.2%
- Genomics, phytochemicals, and oxidative stress2.7%
- Biochemical effects in animals2.3%
- Alcohol Consumption and Health Effects1.6%
- Phytochemicals and Antioxidant Activities1.5%
- Other77.7%
Coauthors
- Naila Rabbani68
- Mingzhan Xue20
- Naila Ahmed15
- Roya Babaei‐Jadidi12
- Antony C. McLellan7
- N. Karachalias7
- Attia Anwar5
- Michael Brownlee5
- Abdelilah Arredouani4
- Aijaz Parray4
- Alberto de la Fuente4
- Essam M. Abdelalim4
- James R. Larkin4
- Lijiang Song4
- Marie Westwood4
- Maryam Al-Motawa4
- Nazeer Ahmed4
- Nehad M. Alajez4
- Omar Albagha4
- Omar M. A. El‐Agnaf4
- Susan A. Phillips4
- Theodore W. C. Lo4
- Amal Adnan Ashour3
- Angelika Bierhaus3
All papers
- Guidelines for measuring reactive oxygen species and oxidative damage in cells and in vivo
Authors: Michael P. Murphy, Hülya Bayır, Vsevolod V. Belousov, Christopher J. Chang, Kelvin J.A. Davies, Michael J. Davies, Tobias P. Dick, Toren Finkel, Henry Jay Forman, Yvonne Janssen‐Heininger, David Gems, Valerian E. Kagan, Balaraman Kalyanaraman, Nils‐Göran Larsson, Ginger L. Milne, Thomas Nyström, Henrik E. Poulsen, Rafael Radí, Holly Van Remmen, Paul T. Schumacker, Paul J. Thornalley, Shinya Toyokuni, Christine C. Winterbourn, Huiyong Yin, Barry Halliwell - Nature Metabolism 2022 cited by 1,321
- Advanced glycation end products in the pathogenesis of chronic kidney disease
Authors: Naila Rabbani, Paul J. Thornalley - Kidney International 2018 cited by 382
- Formation of glyoxal, methylglyoxal and 3-deoxyglucosone in the glycation of proteins by glucose
Authors: Paul J. Thornalley, Annika LANGBORG, Harjit S. Minhas - Biochemical Journal 1999 cited by 1,206
- Unraveling the Biological Roles of Reactive Oxygen Species
Authors: Michael P. Murphy, Arne Holmgren, Nils‐Göran Larsson, Barry Halliwell, Christopher J. Chang, Balaraman Kalyanaraman, Sue Goo Rhee, Paul J. Thornalley, Linda Partridge, David Gems, Thomas Nyström, Vsevolod V. Belousov, Paul T. Schumacker, Christine C. Winterbourn - Cell Metabolism 2011 cited by 821
- Use of aminoguanidine (Pimagedine) to prevent the formation of advanced glycation endproducts
Authors: Paul J. Thornalley - Archives of Biochemistry and Biophysics 2003 cited by 669
- Methylglyoxal modification of Nav1.8 facilitates nociceptive neuron firing and causes hyperalgesia in diabetic neuropathy
Authors: Angelika Bierhaus, Thomas Fleming, Stoyan Stoyanov, Andreas Leffler, Alexandru Babeș, Cristian Neacsu, Susanne K. Sauer, Mirjam Eberhardt, Martina Schnölzer, Felix Lasitschka, Winfried Neuhuber, Tatjana I. Kichko, Ilze Konrāde, Ralf Elvert, Walter Mier, Valdis Pīrāgs, Ivan Krešimir Lukić, Michael Morcos, Thomas Dehmer, Naila Rabbani, Paul J. Thornalley, Diane Edelstein, Carla Nau, Josephine M. Forbes, Per M. Humpert, Markus Schwaninger, Dan Ziegler, David M. Stern, Mark E. Cooper, Uwe Haberkorn, Michael Brownlee, Peter W. Reeh, Peter P. Nawroth - Nature Medicine 2012 cited by 495
- Dicarbonyl stress in cell and tissue dysfunction contributing to ageing and disease
Authors: Naila Rabbani, Paul J. Thornalley - Biochemical and Biophysical Research Communications 2015 cited by 351
- Measurement of methylglyoxal by stable isotopic dilution analysis LC-MS/MS with corroborative prediction in physiological samples
Authors: Naila Rabbani, Paul J. Thornalley - Nature Protocols 2014 cited by 267
- Involvement of a gut–retina axis in protection against dietary glycemia-induced age-related macular degeneration
Authors: Sheldon Rowan, Shuhong Jiang, Tal Korem, Jędrzej Szymański, Min‐Lee Chang, Jason T. Szelog, Christa Cassalman, Kalavathi Dasuri, Christina McGuire, Ryoji Nagai, Xue-Liang Du, Michael Brownlee, Naila Rabbani, Paul J. Thornalley, James Baleja, Amy Deik, Kerry A. Pierce, Justin Scott, Clary B. Clish, Donald E. Smith, Adina Weinberger, Tali Avnit-Sagi, Maya Lotan‐Pompan, Eran Segal, Allen Taylor - National Academy of Sciences, Proceedings of the National Academy of Sciences 2017 cited by 268
- Dicarbonyl Intermediates in the Maillard Reaction
Authors: Paul J. Thornalley - Annals of the New York Academy of Sciences 2005 cited by 454
- PROTEIN AND NUCLEOTIDE DAMAGE BY GLYOXAL AND METHYLGLYOXAL IN PHYSIOLOGICAL SYSTEMS - ROLE IN AGEING AND DISEASE
Authors: Paul J. Thornalley - Drug metabolism and drug interactions 2008 cited by 475
- Transcriptional control of glyoxalase 1 by Nrf2 provides a stress-responsive defence against dicarbonyl glycation
Authors: Mingzhan Xue, Naila Rabbani, Hiroshi Momiji, Precious Imbasi, M. Maqsud Anwar, Neil R. Kitteringham, B. Kevin Park, Tomokazu Souma, Takashi Moriguchi, Masayuki Yamamoto, Paul J. Thornalley - Biochemical Journal 2011 cited by 294
- Activation of the unfolded protein response in high glucose treated endothelial cells is mediated by methylglyoxal
Authors: Zehra Irshad, Mingzhan Xue, Amal Adnan Ashour, James R. Larkin, Paul J. Thornalley, Naila Rabbani - Scientific Reports 2019 cited by 105
- Activity, regulation, copy number and function in the glyoxalase system
Authors: Naila Rabbani, Mingzhan Xue, Paul J. Thornalley - Biochemical Society Transactions 2014 cited by 116
- Binding and modification of proteins by methylglyoxal under physiological conditions. A kinetic and mechanistic study with N alpha-acetylarginine, N alpha-acetylcysteine, and N alpha-acetyllysine, and bovine serum albumin.
Authors: Theodore W. C. Lo, Marie Westwood, Antony C. McLellan, Trevor Selwood, Paul J. Thornalley - Journal of Biological Chemistry 1994 cited by 695
- The formation of methylglyoxal from triose phosphates
Authors: Susan A. Phillips, Paul J. Thornalley - European Journal of Biochemistry 1993 cited by 559
- Methylglyoxal, glyoxalase 1 and the dicarbonyl proteome
Authors: Naila Rabbani, Paul J. Thornalley - Amino Acids 2010 cited by 419
- Protein glycation, oxidation and nitration adduct residues and free adducts of cerebrospinal fluid in Alzheimer's disease and link to cognitive impairment
Authors: Naila Ahmed, Usman Ahmed, Paul J. Thornalley, Klaus Häger, Gerd Fleischer, Gerald Münch - Journal of Neurochemistry 2004 cited by 237
- Hexokinase-2 Glycolytic Overload in Diabetes and Ischemia–Reperfusion Injury
Authors: Naila Rabbani, Paul J. Thornalley - Trends in Endocrinology and Metabolism 2019 cited by 144
- Hexokinase-2-Linked Glycolytic Overload and Unscheduled Glycolysis—Driver of Insulin Resistance and Development of Vascular Complications of Diabetes
Authors: Naila Rabbani, Mingzhan Xue, Paul J. Thornalley - International Journal of Molecular Sciences 2022 cited by 52
- Methylglyoxal-Derived Hydroimidazolone Advanced Glycation End-Products of Human Lens Proteins
Authors: Naila Ahmed, Paul J. Thornalley, Jens Dawczynski, Sybille Franke, J Strobel, Gu ̈nter Stein, GEORGE M. HAIK - Investigative Ophthalmology & Visual Science 2003 cited by 281
- Methylglyoxal-induced dicarbonyl stress in aging and disease: first steps towards glyoxalase 1-based treatments
Authors: Naila Rabbani, Mingzhan Xue, Paul J. Thornalley - Clinical Science 2016 cited by 169
- Glyoxalase I – structure, function and a critical role in the enzymatic defence against glycation
Authors: Paul J. Thornalley - Biochemical Society Transactions 2003 cited by 614
- Improved Glycemic Control and Vascular Function in Overweight and Obese Subjects by Glyoxalase 1 Inducer Formulation
Authors: Mingzhan Xue, Martin O. Weickert, Sheharyar Qureshi, Ngianga‐Bakwin Kandala, Attia Anwar, Molly Waldron, Alaa Shafie, David J. Messenger, Mark Fowler, Gail Jenkins, Naila Rabbani, Paul J. Thornalley - Diabetes 2016 cited by 207
