Perry J. Blackshear
Active 1974–2025
- 127
- Papers
- 21,493
- Citations
- 93
- h-index
- 125
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Biochemistry, Genetics and Molecular Biology56.3%
- Medicine27.6%
- Immunology and Microbiology7.5%
- Neuroscience4%
- Agricultural and Biological Sciences1.9%
- Nursing0.7%
- Other2%
Topics
- RNA Research and Splicing7%
- RNA modifications and cancer4.8%
- RNA and protein synthesis mechanisms3.5%
- Protein Kinase Regulation and GTPase Signaling3.3%
- Cancer-related molecular mechanisms research1.6%
- Cancer Immunotherapy and Biomarkers1.6%
- Other78.2%
Coauthors
- Deborah J. Stumpo28
- Wi S. Lai27
- Elizabeth A. Kennington9
- Ester Carballo9
- Matthias Gaestel7
- Jonathan M. Graff6
- Gregory A. Taylor5
- Ruth S. Phillips5
- Danielle M. Carrick4
- Heping Cao4
- J. David Johnson4
- Michael J. Thompson4
- Raphael A. Nemenoff4
- Sonika Patial4
- Cheryl B. Bock3
- Dimitris L. Kontoyiannis3
- George Kollias3
- Gerald M. Wilson3
- Hossein Ardehali3
- Hsiang‐Chun Chang3
- J.F. Kuo3
- Alexey Kotlyarov2
- Andrew R. Clark2
- Angus C. Nairn2
All papers
- Oncogenic RAS Signaling Promotes Tumor Immunoresistance by Stabilizing PD-L1 mRNA
Authors: Matthew A. Coelho, Sophie de Carné Trécesson, Sareena Rana, Davide Zecchin, Christopher Moore, Míriam Molina‐Arcas, Philip East, Bradley Spencer‐Dene, Emma Nye, Karin Barnouin, Ambrosius P. Snijders, Wi S. Lai, Perry J. Blackshear, Julian Downward - Immunity 2017 cited by 665
- Single-Cell Transcriptomics Uncovers Glial Progenitor Diversity and Cell Fate Determinants during Development and Gliomagenesis
Authors: Qinjie Weng, Jincheng Wang, Jiajia Wang, Danyang He, Zuolin Cheng, Feng Zhang, Ravinder Verma, Lingli Xu, Xinran Dong, Yunfei Liao, Xuelian He, Andrew Potter, Liguo Zhang, Chuntao Zhao, Mei Xin, Qian Zhou, Bruce J. Aronow, Perry J. Blackshear, Jeremy N. Rich, Qiaojun He, Wenhao Zhou, Mario L. Suvà, Ronald R. Waclaw, S. Steven Potter, Guoqiang Yu, Q. Richard Lu - Cell stem cell 2019 cited by 219
- RNA-binding proteins in immune regulation: a focus on CCCH zinc finger proteins
Authors: Mingui Fu, Perry J. Blackshear - Nature reviews. Immunology 2016 cited by 348
- mTOR Regulates Cellular Iron Homeostasis through Tristetraprolin
Authors: Marina Bayeva, Arineh Khechaduri, Sergi Puig, Hsiang‐Chun Chang, Sonika Patial, Perry J. Blackshear, Hossein Ardehali - Cell Metabolism 2012 cited by 203
- APOε4 is associated with enhanced in vivo innate immune responses in human subjects
Authors: Stephen C. Gale, Li Gao, Carmen Mikacenic, Susette M. Coyle, Nicholas Rafaels, Tanda M. Dudenkov, Jennifer H. Madenspacher, David W. Draper, William Ge, Jim J. Aloor, Kathleen M. Azzam, Lihua Lai, Perry J. Blackshear, Steven E. Calvano, Kathleen C. Barnes, Stephen F. Lowry, Siobhan Corbett, Mark M. Wurfel, Michael B. Fessler - Journal of Allergy and Clinical Immunology 2014 cited by 196
- The ZFP36 family of RNA binding proteins regulates homeostatic and autoreactive T cell responses
Authors: Melissa E. Cook, Tara R. Bradstreet, Ashlee M. Webber, Jongshin Kim, Andrea Santeford, Kevin M. Harris, Maegan K Murphy, Jennifer Tran, Nada M. Abdalla, Elizabeth A. Schwarzkopf, Suellen Greco, Carmen M. Halabi, Rajendra S. Apte, Perry J. Blackshear, Brian T. Edelson - Science Immunology 2022 cited by 95
- Feedback Inhibition of Macrophage Tumor Necrosis Factor-α Production by Tristetraprolin
Authors: Ester Carballo, Wi S. Lai, Perry J. Blackshear - Science 1998 cited by 1,171
- A Pathogenetic Role for TNFα in the Syndrome of Cachexia, Arthritis, and Autoimmunity Resulting from Tristetraprolin (TTP) Deficiency
Authors: Gregory A. Taylor, Ester Carballo, David M. Lee, Wi S. Lai, Michael J. Thompson, Dhavalkumar D. Patel, Daniel I. Schenkman, Gary S. Gilkeson, Hal E. Broxmeyer, Barton F. Haynes, Perry J. Blackshear - Immunity 1996 cited by 766
- Chromatin Modification and Global Transcriptional Silencing in the Oocyte Mediated by the mRNA Decay Activator ZFP36L2
Authors: Jennifer N. Chousal, Kyucheol Cho, Madhuvanthi Ramaiah, David Skarbrevik, Sergio Mora-Castilla, Deborah J. Stumpo, Jens Lykke‐Andersen, Louise C. Laurent, Perry J. Blackshear, Miles Wilkinson, Heidi Cook‐Andersen - Developmental Cell 2018 cited by 111
- Evidence that Tristetraprolin Binds to AU-Rich Elements and Promotes the Deadenylation and Destabilization of Tumor Necrosis Factor Alpha mRNA
Authors: Wi S. Lai, Ester Carballo, Julie R. Strum, Elizabeth A. Kennington, Ruth S. Phillips, Perry J. Blackshear - Molecular and Cellular Biology 1999 cited by 728
- Tristetraprolin (TTP): Interactions with mRNA and proteins, and current thoughts on mechanisms of action
Authors: Seth A. Brooks, Perry J. Blackshear - Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 2013 cited by 398
- The RNA-binding protein TTP is a global post-transcriptional regulator of feedback control in inflammation
Authors: Christopher Tiedje, Manuel D. Díaz‐Muñoz, Philipp Trulley, Helena Ahlfors, Kathrin Laaß, Perry J. Blackshear, Martin Turner, Matthias Gaestel - Nucleic Acids Research 2016 cited by 167
- High-Resolution Sequencing and Modeling Identifies Distinct Dynamic RNA Regulatory Strategies
Authors: Michal Rabani, Raktima Raychowdhury, Marko Jovanović, Michael S. Rooney, Deborah J. Stumpo, Andrea Pauli, Nir Hacohen, Alexander F. Schier, Perry J. Blackshear, Nir Friedman, Ido Amit, Aviv Regev - Cell 2014 cited by 249
- mRNA-binding protein tristetraprolin is essential for cardiac response to iron deficiency by regulating mitochondrial function
Authors: Tatsuya Sato, Hsiang‐Chun Chang, Marina Bayeva, Jason Shapiro, Lucía Ramos-Alonso, Hidemichi Kouzu, Xinghang Jiang, Ting Liu, Sumeyye Yar, Konrad Teodor Sawicki, Chunlei Chen, María Teresa Martínez‐Pastor, Deborah J. Stumpo, Paul T. Schumacker, Perry J. Blackshear, Issam Ben‐Sahra, Sergi Puig, Hossein Ardehali - National Academy of Sciences, Proceedings of the National Academy of Sciences 2018 cited by 89
- Structural basis for the recruitment of the human CCR4–NOT deadenylase complex by tristetraprolin
Authors: Marc R. Fabian, Filipp Frank, Christopher Rouya, Nadeem Siddiqui, Wi S. Lai, Alexey Karetnikov, Perry J. Blackshear, Bhushan Nagar, Nahum Sonenberg - Nature Structural & Molecular Biology 2013 cited by 279
- Inhibiting transcription in cultured metazoan cells with actinomycin D to monitor mRNA turnover
Authors: Wi S. Lai, René M. Arvola, Aaron C. Goldstrohm, Perry J. Blackshear - Methods 2019 cited by 83
- The Arabidopsis Tandem Zinc Finger Protein AtTZF1 Traffics between the Nucleus and Cytoplasmic Foci and Binds Both DNA and RNA
Authors: Marcelo Pomeranz, Cyrus Hah, Pei‐Chi Lin, Shin Gene Kang, John J. Finer, Perry J. Blackshear, Jyan-Chyun Jang - PLANT PHYSIOLOGY 2009 cited by 206
- HuR as a Negative Posttranscriptional Modulator in Inflammation
Authors: Vicky Katsanou, Olympia Papadaki, Stavros Milatos, Perry J. Blackshear, Paul Anderson, George Kollias, Dimitris L. Kontoyiannis - Molecular Cell 2005 cited by 237
- Global target mRNA specification and regulation by the RNA-binding protein ZFP36
Authors: Neelanjan Mukherjee, Nicholas C. Jacobs, Markus Hafner, Elizabeth A. Kennington, Jeffrey D. Nusbaum, Thomas Tuschl, Perry J. Blackshear, Uwe Ohler - Genome biology 2014 cited by 165
- The CCCH tandem zinc-finger protein Zfp36l2 is crucial for female fertility and early embryonic development
Authors: Silvia B. V. Ramos, Deborah J. Stumpo, Elizabeth A. Kennington, Ruth S. Phillips, Cheryl B. Bock, Fernando Ribeiro-Neto, Perry J. Blackshear - Development 2004 cited by 156
- Interactions of CCCH Zinc Finger Proteins with mRNA
Authors: Wi S. Lai, Ester Carballo, Judith M. Thorn, Elizabeth A. Kennington, Perry J. Blackshear - Journal of Biological Chemistry 2000 cited by 373
- Tip60- and sirtuin 2-regulated MARCKS acetylation and phosphorylation are required for diabetic embryopathy
Authors: Penghua Yang, Cheng Xu, E. Albert Reece, Xi Chen, Jianxiang Zhong, Min Zhan, Deborah J. Stumpo, Perry J. Blackshear, Peixin Yang, Peixin Yang, Peixin Yang - Nature Communications 2019 cited by 40
- Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 Regulates Tumor Necrosis Factor mRNA Stability and Translation Mainly by Altering Tristetraprolin Expression, Stability, and Binding to Adenine/Uridine-Rich Element
Authors: Edward Hitti, Tatiana Iakovleva, Matthew Brook, Stefanie Deppenmeier, Achim D. Gruber, Danuta Radzioch, Andrew R. Clark, Perry J. Blackshear, Alexey Kotlyarov, Matthias Gaestel - Molecular and Cellular Biology 2006 cited by 387
- Interleukin‐10 targets p38 MAPK to modulate ARE‐dependent TNF mRNA translation and limit intestinal pathology
Authors: Dimitris L. Kontoyiannis, Alexey Kotlyarov, Ester Carballo, Lena Alexopoulou, Perry J. Blackshear, Matthias Gaestel, Roger J. Davis, Richard A. Flavell, George Kollias - The EMBO Journal 2001 cited by 255
