Peter C. Heinrich
Active 1972–2011
- 104
- Papers
- 26,925
- Citations
- 85
- h-index
- 104
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Medicine61.8%
- Biochemistry, Genetics and Molecular Biology16.6%
- Immunology and Microbiology10.2%
- Neuroscience5.4%
- Agricultural and Biological Sciences1.2%
- Nursing1%
- Other3.8%
Topics
- Cytokine Signaling Pathways and Interactions10.1%
- Immune Response and Inflammation2.5%
- Adipokines, Inflammation, and Metabolic Diseases2.2%
- Immune Cell Function and Interaction2.1%
- interferon and immune responses2%
- NF-κB Signaling Pathways1.5%
- Other79.6%
Coauthors
- Fred Schaper18
- Lutz Graeve18
- Stefan Rose‐John16
- Gerhard Müller‐Newen15
- Iris Behrmann15
- Friedemann Horn11
- Serge Haan10
- Tilo Andus10
- Toshio Hirano9
- Heidi Schooltink8
- José V. Castell8
- Tadamitsu Kishimoto8
- Heike M. Hermanns7
- Johannes G. Bode7
- Andrea Küster6
- Claudia Lütticken6
- Dieter Häussinger6
- Jochen Schmitz6
- Jürgen Müllberg6
- Thomas Geiger6
- Ulrike Hemmann6
- Elke Dittrich5
- Heike Dahmen5
- Simone Radtke5
All papers
- Principles of interleukin (IL)-6-type cytokine signalling and its regulation
Authors: Peter C. Heinrich, Iris Behrmann, Serge Haan, Heike M. Hermanns, Gerhard Müller‐Newen, Fred Schaper - Biochemical Journal 2003 cited by 3,245
- Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathway
Authors: Peter C. Heinrich, Iris Behrmann, Gerhard Müller‐Newen, Fred Schaper, Lutz Graeve - Biochemical Journal 1998 cited by 2,129
- Interleukin-6 and the acute phase response
Authors: Peter C. Heinrich, José V. Castell, Tilo Andus - Biochemical Journal 1990 cited by 2,763
- Interleukin‐6 is the major regulator of acute phase protein synthesis in adult human hepatocytes
Authors: José V. Castell, Marı́a José Gómez-Lechón, Martina David, Tilo Andus, Thomas Geiger, Ramón Trullenque, Ricardo Fabra, Peter C. Heinrich - FEBS Letters 1989 cited by 901
- Hepatic acute phase proteins – Regulation by IL-6- and IL-1-type cytokines involving STAT3 and its crosstalk with NF-κB-dependent signaling
Authors: Johannes G. Bode, Ute Albrecht, Dieter Häussinger, Peter C. Heinrich, Fred Schaper - European Journal of Cell Biology 2011 cited by 371
- Soluble receptors for cytokines and growth factors: generation and biological function
Authors: Stefan Rose‐John, Peter C. Heinrich - Biochemical Journal 1994 cited by 777
- Enhanced expression levels of IL-31 correlate with IL-4 and IL-13 in atopic and allergic contact dermatitis
Authors: Mark M. Neis, Bettina Peters, Alexandra Dreuw, Joerg Wenzel, Thomas Bieber, Cornelia Mauch, Thomas Krieg, S Stanzel, Peter C. Heinrich, Hans F. Merk, Andreas Bosio, Jens M. Baron, Heike M. Hermanns - Journal of Allergy and Clinical Immunology 2006 cited by 379
- The soluble interleukin‐6 receptor is generated by shedding
Authors: Jürgen Mülberg, Heidi Schooltink, Tanja Stoyan, Monika Günther, Lutz Graeve, Gerhard Buse, Andrzej Maćkiewicz, Peter C. Heinrich, Stefan Rose‐John - European Journal of Immunology 1993 cited by 512
- Acute-phase response of human hepatocytes: Regulation of acute-phase protein synthesis by interleukin-6
Authors: José V. Castell, Marı́a José Gómez-Lechón, Martina David, Ricardo Fabra, Ramón Trullenque, Peter C. Heinrich - Hepatology 1990 cited by 756
- Association of Transcription Factor APRF and Protein Kinase Jak1 with the Interleukin-6 Signal Transducer gp130
Authors: Claudia Lütticken, Ursula Maria Wegenka, Juping Yuan, Jan Buschmann, Chris Schindler, Andrew Ziemiecki, Ailsa G. Harpur, Andrew F. Wilks, Kiyoshi Yasukawa, Tetsuya Taga, Tadamitsu Kishimoto, Giovanna Barbieri, Sandra Pellegrini, Michael Sendtner, Peter C. Heinrich, Friedemann Horn - Science 1994 cited by 823
- Recombinant human interleukin‐6 (IL‐6/BSF‐2/HSF) regulates the synthesis of acute phase proteins in human hepatocytes
Authors: José V. Castell, Marı́a José Gómez-Lechón, Martina David, Toshio Hirano, Tadamitsu Kishimoto, Peter C. Heinrich - FEBS Letters 1988 cited by 457
- Activation of STAT3 by IL-6 and IL-10 in Primary Human Macrophages Is Differentially Modulated by Suppressor of Cytokine Signaling 3
Authors: Claudia Niemand, Ariane Nimmesgern, Serge Haan, Patrick Fischer, Fred Schaper, Rolf Rossaint, Peter C. Heinrich, Gerhard Müller‐Newen - The Journal of Immunology 2003 cited by 356
- A major role for the protein tyrosine kinase JAK1 in the JAK/STAT signal transduction pathway in response to interleukin‐6.
Authors: Dmitry Guschin, Neil C. Rogers, James Briscoe, Bruce A. Witthuhn, Diane Watling, Friedemann Horn, Sandra Pellegrini, Kiyoshi Yasukawa, Peter C. Heinrich, George R. Stark - The EMBO Journal 1995 cited by 434
- LPS and TNFα induce SOCS3 mRNA and inhibit IL‐6‐induced activation of STAT3 in macrophages
Authors: Johannes G. Bode, Ariane Nimmesgern, Jochen Schmitz, Fred Schaper, Marcus Schmitt, Wiltrud Frisch, Dieter Häussinger, Peter C. Heinrich, Lutz Graeve - FEBS Letters 1999 cited by 199
- Characterization of Methylthioadenosin Phosphorylase (MTAP) Expression in Malignant Melanoma
Authors: Iris Behrmann, Susanne Wallner, Waraporn Komyod, Peter C. Heinrich, Marion Schuierer, Reinhard Buettner, Anja‐Katrin Bosserhoff - American Journal Of Pathology 2003 cited by 144
- Interleukin‐6 is a direct mediator of T cell migration
Authors: Manuela Weißenbach, Thomas Clahsen, Christian Weber, D. Spitzer, Dagmar Wirth, Dietmar Vestweber, Peter C. Heinrich, Fred Schaper - European Journal of Immunology 2004 cited by 111
- Interferon-γ-Mediated Growth Regulation of Melanoma Cells: Involvement of STAT1-Dependent and STAT1-Independent Signals
Authors: Anja‐Katrin Bosserhoff, Marcin Kortylewski, Waraporn Komyod, Maria-Elisabeth Kauffmann, Peter C. Heinrich, Iris Behrmann - Journal of Investigative Dermatology 2004 cited by 92
- Plasma clearance, organ distribution and target cells of interleukin‐6/hepatocyte‐stimulating factor in the rat
Authors: José V. Castell, Thomas Geiger, Volker Groß, Tilo Andus, Eicke WALTER, Toshio Hirano, Tadamitsu Kishimoto, Peter C. Heinrich - European Journal of Biochemistry 1988 cited by 295
- Soluble IL-6 Receptor Potentiates the Antagonistic Activity of Soluble gp130 on IL-6 Responses
Authors: Gerhard Müller‐Newen, Andrea Küster, Ulrike Hemmann, Radovan Keul, Ursula Horsten, Astrid Martens, Lutz Graeve, John Wijdenes, Peter C. Heinrich - The Journal of Immunology 1998 cited by 164
- Differential Activation of Acute Phase Response Factor/Stat3 and Stat1 via the Cytoplasmic Domain of the Interleukin 6 Signal Transducer gp130
Authors: Ulrike Hemmann, Claudia Gerhartz, Birgit Heesel, Jürgen Sasse, Günther Kurapkat, Joachim Grötzinger, Axel Wollmer, Zhong Zhong, James Darnell, Lutz Graeve, Peter C. Heinrich, Friedemann Horn - Journal of Biological Chemistry 1996 cited by 244
- Structure-function analysis of interleukin-6 utilizing human/murine chimeric molecules. Involvement of two separate domains in receptor binding
Authors: M. van Dam, Jürgen Müllberg, Heidi Schooltink, Tanja Stoyan, Just P. J. Brakenhoff, Lutz Graeve, Peter C. Heinrich, Stefan Rose‐John - Journal of Biological Chemistry 1993 cited by 112
- Importance of the Membrane-Proximal Extracellular Domains for Activation of the Signal Transducer Glycoprotein 130
Authors: Ingo Kurth, Ursula Horsten, Stefan Pflanz, Andreas Timmermann, Andrea Küster, Heike Dahmen, Ingrid Tacken, Peter C. Heinrich, Gerhard Müller‐Newen - The Journal of Immunology 2000 cited by 79
- Acute-phase response factor, a nuclear factor binding to acute-phase response elements, is rapidly activated by interleukin-6 at the posttranslational level.
Authors: Ursula Maria Wegenka, Jan Buschmann, Claudia Lütticken, Peter C. Heinrich, Friedemann Horn - Molecular and Cellular Biology 1993 cited by 541
- SOCS3 Exerts Its Inhibitory Function on Interleukin-6 Signal Transduction through the SHP2 Recruitment Site of gp130
Authors: Jochen Schmitz, Manuela Weißenbach, Serge Haan, Peter C. Heinrich, Fred Schaper - Journal of Biological Chemistry 2000 cited by 394
