Philippe P. Roux
Active 1998–2025
- 69
- Papers
- 19,530
- Citations
- 52
- h-index
- 67
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Biochemistry, Genetics and Molecular Biology53%
- Medicine26.7%
- Neuroscience8.6%
- Immunology and Microbiology5.2%
- Agricultural and Biological Sciences1.6%
- Nursing1.2%
- Other3.7%
Topics
- PI3K/AKT/mTOR signaling in cancer5.8%
- Protein Kinase Regulation and GTPase Signaling2.1%
- Melanoma and MAPK Pathways2%
- Cellular Mechanics and Interactions1.9%
- Nerve injury and regeneration1.7%
- RNA modifications and cancer1.7%
- Other84.8%
Coauthors
- Geneviève Lavoie14
- John Blenis11
- Léo Aubert9
- Pierre Thibault9
- Joseph Tcherkezian7
- Yves Roméo7
- Bryan A. Ballif6
- Ewa K. Paluch6
- Sébastien Lemieux6
- Audrey Carrière5
- Guillaume Charras5
- Guy Sauvageau5
- Patrick Gendron5
- Sami Nourreddine5
- Thibault Houlès5
- Éric Bonneil5
- Jalila Chagraoui4
- Jean-François Spinella4
- Josée Hébert4
- Marie Cargnello4
- Nadine Mayotte4
- Steven P. Gygi4
- Antoine Méant3
- Azer Farah3
All papers
- Activation and Function of the MAPKs and Their Substrates, the MAPK-Activated Protein Kinases
Authors: Marie Cargnello, Philippe P. Roux - Microbiology and Molecular Biology Reviews 2011 cited by 3,257
- ERK and p38 MAPK-Activated Protein Kinases: a Family of Protein Kinases with Diverse Biological Functions
Authors: Philippe P. Roux, John Blenis - Microbiology and Molecular Biology Reviews 2004 cited by 2,501
- Copper bioavailability is a KRAS-specific vulnerability in colorectal cancer
Authors: Léo Aubert, Neethi Nandagopal, Zachary Steinhart, Geneviève Lavoie, Sami Nourreddine, Jacob M. Berman, Marc K. Saba-El-Leil, David Papadopoli, Sichun Lin, Traver Hart, Graham MacLeod, Ivan Topisirović, Louis Gaboury, Christoph J. Fahrni, Daniel Schramek, Sylvain Meloche, Stéphane Angers, Philippe P. Roux - Nature Communications 2020 cited by 314
- Actin cortex architecture regulates cell surface tension
Authors: Priyamvada Chugh, Andrew G. Clark, Matthew B. Smith, Davide A. D. Cassani, Kai Dierkes, Anan Ragab, Philippe P. Roux, Guillaume Charras, Guillaume Salbreux, Ewa K. Paluch - Nature Cell Biology 2017 cited by 504
- Tuberous Sclerosis Complex Gene Products, Tuberin and Hamartin, Control mTOR Signaling by Acting as a GTPase-Activating Protein Complex toward Rheb
Authors: Andrew R. Tee, Brendan D. Manning, Philippe P. Roux, Lewis C. Cantley, John Blenis - Current Biology 2003 cited by 1,210
- Mubritinib Targets the Electron Transport Chain Complex I and Reveals the Landscape of OXPHOS Dependency in Acute Myeloid Leukemia
Authors: Irène Baccelli, Yves Gareau, Bernhard Lehnertz, Stéphane Gingras, Jean-François Spinella, Sophie Corneau, Nadine Mayotte, Simon Girard, Mélanie Fréchette, Valérie Blouin-Chagnon, Koryne Leveillé, Isabel Boivin, Tara MacRae, Jana Krošl, Clarisse Thiollier, Vincent‐Philippe Lavallée, Evgeny Kanshin, Thierry Bertomeu, Jasmin Coulombe‐Huntington, Corinne St‐Denis, Marie-Ève Bordeleau, Geneviève Boucher, Philippe P. Roux, Sébastien Lemieux, Mike Tyers, Pierre Thibault, Josée Hébert, Anne Marinier, Guy Sauvageau - Cancer Cell 2019 cited by 262
- Signaling Pathways Involved in the Regulation of mRNA Translation
Authors: Philippe P. Roux, Ivan Topisirović - Molecular and Cellular Biology 2018 cited by 324
- Rapamycin differentially inhibits S6Ks and 4E-BP1 to mediate cell-type-specific repression of mRNA translation
Authors: Andrew Y. Choo, Sang-Oh Yoon, Sang Gyun Kim, Philippe P. Roux, John Blenis - National Academy of Sciences, Proceedings of the National Academy of Sciences 2008 cited by 794
- The Receptor Tyrosine Kinase AXL Is Required at Multiple Steps of the Metastatic Cascade during HER2-Positive Breast Cancer Progression
Authors: Marie-Anne Goyette, Stéphanie Duhamel, Léo Aubert, Ariane Pelletier, Paul Savage, Marie‐Pier Thibault, Radia Marie Johnson, Peter Carmeliet, Mark Basik, Louis Gaboury, William J. Muller, Morag Park, Philippe P. Roux, Jean‐Philippe Gratton, Jean‐François Côté - Cell Reports 2018 cited by 144
- RAS/ERK Signaling Promotes Site-specific Ribosomal Protein S6 Phosphorylation via RSK and Stimulates Cap-dependent Translation
Authors: Philippe P. Roux, David Shahbazian, Hieu Vu, Marina K. Holz, Michael S. Cohen, Jack Taunton, Nahum Sonenberg, John Blenis - Journal of Biological Chemistry 2007 cited by 758
- ERK1/2 Phosphorylate Raptor to Promote Ras-dependent Activation of mTOR Complex 1 (mTORC1)
Authors: Audrey Carrière, Yves Roméo, Hugo A. Acosta-Jaquez, Julie Moreau, Éric Bonneil, Pierre Thibault, Diane C. Fingar, Philippe P. Roux - Journal of Biological Chemistry 2010 cited by 267
- mTORC2 can associate with ribosomes to promote cotranslational phosphorylation and stability of nascent Akt polypeptide
Authors: Won Jun Oh, Chang -chih Wu, Sung Jin Kim, Valeria Facchinetti, Louis -André Julien, Monica Finlan, Philippe P. Roux, Bing Su, Estela Jacinto - The EMBO Journal 2010 cited by 331
- A new inhibitor of the β-arrestin/AP2 endocytic complex reveals interplay between GPCR internalization and signalling
Authors: Alexandre Beautrait, Justine S. Paradis, Brandon Zimmerman, Jenna Giubilaro, Ljiljana Nikolajev, Sylvain Armando, Hiroyuki Kobayashi, Lama Yamani, Yoon Namkung, Franziska M. Heydenreich, Étienne Khoury, Martin Audet, Philippe P. Roux, Dmitry B. Veprintsev, Stéphane A. Laporte, Michel Bouvier - Nature Communications 2017 cited by 219
- Tumor-promoting phorbol esters and activated Ras inactivate the tuberous sclerosis tumor suppressor complex via p90 ribosomal S6 kinase
Authors: Philippe P. Roux, Bryan A. Ballif, Rana Anjum, Steven P. Gygi, John Blenis - National Academy of Sciences, Proceedings of the National Academy of Sciences 2004 cited by 741
- Cellular Control of Cortical Actin Nucleation
Authors: Miia Bovellan, Yves Roméo, Maté Biro, Annett Boden, Priyamvada Chugh, Amina Yonis, Malti Vaghela, Marco Fritzsche, Dale Moulding, Richard Thorogate, Antoine Jégou, Adrian J. Thrasher, Guillaume Romet‐Lemonne, Philippe P. Roux, Ewa K. Paluch, Guillaume Charras - Current Biology 2014 cited by 253
- EPCR expression marks UM171-expanded CD34+ cord blood stem cells
Authors: Iman Fares, Jalila Chagraoui, Bernhard Lehnertz, Tara MacRae, Nadine Mayotte, Elisa Tomellini, Léo Aubert, Philippe P. Roux, Guy Sauvageau - Blood 2017 cited by 225
- In vivo CRISPR screens reveal Serpinb9 and Adam2 as regulators of immune therapy response in lung cancer
Authors: Dzana Dervovic, Ahmad Malik, Edward L.Y. Chen, Masahiro Narimatsu, Nina Adler, Somaieh Afiuni‐Zadeh, Dagmar Krenbek, Sébastien Martinez, Ricky Tsai, Jonathan Boucher, Jacob M. Berman, Katie Teng, Arshad Ayyaz, YiQing Lü, Geraldine Mbamalu, Sampath K. Loganathan, Jongbok Lee, Li Zhang, Cynthia J. Guidos, Jeffrey L. Wrana, Arschang Valipour, Philippe P. Roux, Jüri Reimand, Hartland W. Jackson, Daniel Schramek - Nature Communications 2023 cited by 40
- Oncogenic MAPK Signaling Stimulates mTORC1 Activity by Promoting RSK-Mediated Raptor Phosphorylation
Authors: Audrey Carrière, Marie Cargnello, Louis-André Julien, Huanhuan Gao, Éric Bonneil, Pierre Thibault, Philippe P. Roux - Current Biology 2008 cited by 336
- Regulation and function of the RSK family of protein kinases
Authors: Yves Roméo, Xiaocui Zhang, Philippe P. Roux - Biochemical Journal 2011 cited by 376
- F-Actin Interactome Reveals Vimentin as a Key Regulator of Actin Organization and Cell Mechanics in Mitosis
Authors: Murielle P. Serres, Matthias Samwer, Binh An Truong Quang, Geneviève Lavoie, Upamali Perera, Dirk Görlich, Guillaume Charras, Mark Petronczki, Philippe P. Roux, Ewa K. Paluch - Developmental Cell 2020 cited by 101
- Neurotrophin signaling through the p75 neurotrophin receptor
Authors: Philippe P. Roux - Progress in Neurobiology 2002 cited by 709
- Proteomic analysis of cap-dependent translation identifies LARP1 as a key regulator of 5′TOP mRNA translation
Authors: Joseph Tcherkezian, Marie Cargnello, Yves Roméo, Edward L. Huttlin, Geneviève Lavoie, Steven P. Gygi, Philippe P. Roux - Genes & Development 2014 cited by 263
- Loss of DP1 Aggravates Vascular Remodeling in Pulmonary Arterial Hypertension Via mTORC1 Signaling
Authors: Yuhu He, Caojian Zuo, Daile Jia, Peiyuan Bai, Deping Kong, Di Chen, Guizhu Liu, Juanjuan Li, Yuanyang Wang, Guilin Chen, Shuai Yan, Bing Xiao, Jian Zhang, Lingjuan Piao, Yanli Li, Yizhen Deng, Bin Li, Philippe P. Roux, Katrin I. Andreasson, Richard Breyer, Yunchao Su, Jian Wang, Ankang Lyu, Yujun Shen, Ying Yu - American Journal of Respiratory and Critical Care Medicine 2020 cited by 77
- The mTOR/PI3K and MAPK pathways converge on eIF4B to control its phosphorylation and activity
Authors: David Shahbazian, Philippe P. Roux, Virginie Mieulet, Michael S. Cohen, Brian Raught, Jack Taunton, John W.B. Hershey, John Blenis, Mario Pende, Nahum Sonenberg - The EMBO Journal 2006 cited by 526
