Ralf Kühn
Active 1977–2025
- Also published as
- Ralf Kuhn
- 95
- Papers
- 29,667
- Citations
- 73
- h-index
- 93
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Biochemistry, Genetics and Molecular Biology40.7%
- Immunology and Microbiology22.1%
- Medicine21.8%
- Neuroscience10%
- Agricultural and Biological Sciences2.2%
- Physics and Astronomy1.1%
- Other2.1%
Topics
- Immune Cell Function and Interaction5.4%
- T-cell and B-cell Immunology4.7%
- CRISPR and Genetic Engineering3.4%
- Immunotherapy and Immune Responses2.5%
- Immune Response and Inflammation2.2%
- Circular RNAs in diseases2.1%
- Other79.7%
Coauthors
- Klaus Rajewsky24
- Werner Müller17
- Wolfgang Wurst13
- Van Trung Chu9
- Ngoc Tung Tran7
- Robin Graf7
- F. Gasparini6
- Peter J. Flor6
- D Rennick5
- Martin Hrabě de Angelis5
- Snežana Lukić5
- Thomas Knöpfel5
- Carmen Birchmeier4
- Daniel Berg4
- Ferdinando Nicoletti4
- Sara Hieny4
- T Leonhardt4
- Timm Weber4
- Valeria Bruno4
- Xun Li4
- Agnieszka Rybak‐Wolf3
- Allen W. Cheever3
- Benedikt Wefers3
- Doris Rüegg3
All papers
- Loss of a mammalian circular RNA locus causes miRNA deregulation and affects brain function
Authors: Monika Piwecka, Petar Glažar, Luis R. Hernández-Miranda, Sebastian Memczak, Susanne A. Wolf, Agnieszka Rybak‐Wolf, Andrei Filipchyk, Filippos Klironomos, C Cerda, Pascal Fenske, Thorsten Trimbuch, Vera Zywitza, Mireya Plass, Luisa Schreyer, Salah Ayoub, Christine Kocks, Ralf Kühn, Christian Rosenmund, Carmen Birchmeier, Nikolaus Rajewsky - Science 2017 cited by 1,274
- Interleukin-10-deficient mice develop chronic enterocolitis
Authors: Ralf Kühn, Jürgen Löhler, D Rennick, Klaus Rajewsky, Werner Müller - Cell 1993 cited by 4,311
- Cell-type-specific profiling of brain mitochondria reveals functional and molecular diversity
Authors: Caroline Fecher, Laura Trovò, Stephan A. Müller, Nicolas Snaidero, Jennifer Wettmarshausen, Sylvia Heink, Oskar Ortiz, Ingrid Wagner, Ralf Kühn, J. Hartmann, Rosa Maria Karl, Arthur Konnerth, Thomas Korn, Wolfgang Wurst, Doron Merkler, Stefan F. Lichtenthaler, Fabiana Perocchi, Thomas Misgeld - Nature Neuroscience 2019 cited by 335
- Increasing the efficiency of homology-directed repair for CRISPR-Cas9-induced precise gene editing in mammalian cells
Authors: Van Trung Chu, Timm Weber, Benedikt Wefers, Wolfgang Wurst, Sandrine Sander, Klaus Rajewsky, Ralf Kühn - Nature Biotechnology 2015 cited by 1,246
- Efficient generation of Rosa26 knock-in mice using CRISPR/Cas9 in C57BL/6 zygotes
Authors: Van Trung Chu, Timm Weber, Robin Graf, Thomas Sommermann, Kerstin Petsch, Ulrike Sack, Pavel Volchkov, Klaus Rajewsky, Ralf Kühn - BMC Biotechnology 2016 cited by 358
- A B cell-deficient mouse by targeted disruption of the membrane exon of the immunoglobulin μ chain gene
Authors: Daisuke Kitamura, Jürgen Roes, Ralf Kühn, Klaus Rajewsky - Nature 1991 cited by 1,799
- Development of an intein-mediated split–Cas9 system for gene therapy
Authors: Dong‐Jiunn Jeffery Truong, Karin Kühner, Ralf Kühn, Stanislas Werfel, Stefan Engelhardt, Wolfgang Wurst, Oskar Ortiz - Nucleic Acids Research 2015 cited by 376
- Defective metabolic programming impairs early neuronal morphogenesis in neural cultures and an organoid model of Leigh syndrome
Authors: Gizem Inak, Agnieszka Rybak‐Wolf, Paweł Lisowski, Tancredi Massimo Pentimalli, René Jüttner, Petar Glažar, Karan Uppal, Emanuela Bottani, Dario Brunetti, Christopher Secker, Annika Zink, David Meierhofer, Marie‐Thérèse Henke, Monishita Dey, Ummi Ciptasari, Barbara Mlody, Tobias Hahn, Maria Berruezo-Llacuna, Nikos Karaiskos, Michela Di Virgilio, Johannes A. Mayr, Saskia B. Wortmann, Josef Priller, Michael Gotthardt, Dean P. Jones, Ertan Mayatepek, Werner Stenzel, Sebastian Diecke, Ralf Kühn, Erich E. Wanker, Nikolaus Rajewsky, Markus Schuelke, Alessandro Prigione - Nature Communications 2021 cited by 137
- Inducible Gene Targeting in Mice
Authors: Ralf Kühn, Frieder Schwenk, Michel Aguet, Klaus Rajewsky - Science 1995 cited by 1,943
- Standard methods for maintaining adultApis melliferain cages underin vitrolaboratory conditions
Authors: Geoffrey R. Williams, Cédric Alaux, Cecília Costa, Tamás Csáki, Vincent Doublet, Dorothea Eisenhardt, Ingemar Fries, Ralf Kühn, Dino P. McMahon, Piotr Mędrzycki, Tomás E. Murray, Myrsini E. Natsopoulou, Peter Neumann, Randy Oliver, Robert J. Paxton, Stephen F. Pernal, Dave Shutler, Gina Tanner, J.J.M. van der Steen, Robert Brodschneider - Journal of Apicultural Research 2013 cited by 357
- Microglia sense neuronal activity via GABA in the early postnatal hippocampus
Authors: Francesca Logiacco, Pengfei Xia, Svilen Veselinov Georgiev, Celeste Franconi, Yi‐Jen Chang, Bilge Ugursu, Anje Sporbert, Ralf Kühn, Helmut Kettenmann, Marcus Semtner - Cell Reports 2021 cited by 73
- In vivo dissection of a clustered-CTCF domain boundary reveals developmental principles of regulatory insulation
Authors: Chiara Anania, Rafael D. Acemel, Johanna Jedamzick, Adriano Bolondi, Giulia Cova, Norbert Brieske, Ralf Kühn, Lars Wittler, Francisca M. Real, Darío G. Lupiáñez - Nature Genetics 2022 cited by 85
- Mechanical forces couple bone matrix mineralization with inhibition of angiogenesis to limit adolescent bone growth
Authors: Maria Dzamukova, Tobias M. Brunner, Jadwiga Miotla‐Zarebska, Frederik Heinrich, Laura Brylka, Mir‐Farzin Mashreghi, Anjali P. Kusumbe, Ralf Kühn, Thorsten Schinke, Tonia L. Vincent, Max Löhning - Nature Communications 2022 cited by 69
- Enterocolitis and colon cancer in interleukin-10-deficient mice are associated with aberrant cytokine production and CD4(+) TH1-like responses.
Authors: Daniel Berg, N Davidson, Ralf Kühn, Werner Müller, Satish Menon, G. Holland, LuAnn Thompson-Snipes, Michael W. Leach, D Rennick - Journal of Clinical Investigation 1996 cited by 1,139
- A resource of targeted mutant mouse lines for 5,061 genes
Authors: Marie‐Christine Birling, Atsushi Yoshiki, David J. Adams, Shinya Ayabe, Arthur L. Beaudet, Joanna Bottomley, Allan Bradley, Steve D. M. Brown, Antje Bürger, Wendy Bushell, Francesco Chiani, Hsian‐Jean Chin, Skevoulla Christou, Gemma Codner, Francesco J. DeMayo, Mary E. Dickinson, Brendan Doe, Leah Rae Donahue, Martin Fray, Alessia Gambadoro, Xiang Gao, Marina Gertsenstein, Alba Gomez-Segura, Leslie O. Goodwin, Jason D. Heaney, Yann Hérault, Martin Hrabě de Angelis, Si‐Tse Jiang, Monica J. Justice, Petr Kašpárek, Ruairidh King, Ralf Kühn, Ho Lee, Young Jae Lee, Zhiwei Liu, K. C. Kent Lloyd, Isabel Lorenzo, Ann‐Marie Mallon, Colin McKerlie, Terrence F. Meehan, Violeta Muñoz‐Fuentes, Stuart Newman, Lauryl M. J. Nutter, Goo Taeg Oh, Guillaume Pavlovic, Ramiro Ramírez‐Solis, Barry P. Rosen, Edward J. Ryder, Luís Santos, Joel Schick, John R. Seavitt, Radislav Sedláček, Claudia Seisenberger, Je Kyung Seong, William C. Skarnes, Tania Sorg, Karen P. Steel, Masaru Tamura, Glauco P. Tocchini‐Valentini, Chi‐Kuang Leo Wang, Hannah Wardle‐Jones, Marie Wattenhofer‐Donzé, Sara Wells, Michael V. Wiles, Brandon Willis, Joshua A. Wood, Wolfgang Wurst, Ying Xu, Juan Gallegos, Jennie R. Green, Ritu Bohat, Katie Zimmel, Monica Pereira, S. MacMaster, Sandra Tondat, Linda Wei, Tracy Carroll, Jorge Cabezas, Qing Fan-Lan, Elsa Jacob, Amie Creighton, Patricia Castellanos-Penton, Ozge Danisment, Shannon Clarke, Joanna Joeng, Deborah F. Kelly, Christine To, Rebekah van Bruggen, Valerie Gailus-Durner, Helmut Fuchs, Susan Marschall, Stefanie Dunst, Markus Romberger, Bernhard Rey, Sabine Fessele, Philipp Gormanns, Roland H. Friedel, Cornelia Kaloff, Andreas Hörlein, Sandy Teichmann and 125 more - Nature Genetics 2021 cited by 114
- Prox2 and Runx3 vagal sensory neurons regulate esophageal motility
Authors: Elijah D. Lowenstein, Pierre-Louis Ruffault, Aristotelis Misios, Kate L. Osman, Huimin Li, Rachel S. Greenberg, Rebecca Thompson, Kun Song, Stephan Dietrich, Xun Li, Nikita Vladimirov, Andrew Woehler, Jean‐François Brunet, Niccolò Zampieri, Ralf Kühn, Stephen D. Liberles, Shiqi Jia, Gary R. Lewin, Nikolaus Rajewsky, Teresa E. Lever, Carmen Birchmeier - Neuron 2023 cited by 41
- Essential Role for TrkB Receptors in Hippocampus-Mediated Learning
Authors: Liliana Minichiello, Martin Körte, David P Wolfer, Ralf Kühn, Klaus Unsicker, Vincenzo Cestari, Clelia Rossi‐Arnaud, Hans‐Peter Lipp, Tobias Bonhoeffer, Rüdiger Klein - Neuron 1999 cited by 799
- IL-9 production of naive CD4+ T cells depends on IL-2, is synergistically enhanced by a combination of TGF- beta and IL-4, and is inhibited by IFN-gamma.
Authors: Edgar Schmitt, Tieno Germann, Sigrid Goedert, Petra Hoehn, Christoph Huels, Stephan Koelsch, Ralf Kühn, Werner Müller, Norbert Palm, Erwin Rüde - The Journal of Immunology 1994 cited by 293
- Mutations in Disordered Regions Can Cause Disease by Creating Dileucine Motifs
Authors: Katrina Meyer, Marieluise Kirchner, Bora Uyar, Jingyuan Cheng, Giulia Russo, Luis R. Hernández-Miranda, Anna Szymborska, Henrik Zauber, Ina-Maria Rudolph, Thomas E. Willnow, Altuna Akalin, Volker Haucke, Holger Gerhardt, Carmen Birchmeier, Ralf Kühn, M. Krauß, Sebastian Diecke, Juan M. Pascual, Matthias Selbach - Cell 2018 cited by 140
- In Vivo Ablation of Surface Immunoglobulin on Mature B Cells by Inducible Gene Targeting Results in Rapid Cell Death
Authors: Kong‐Peng Lam, Ralf Kühn, Klaus Rajewsky - Cell 1997 cited by 1,106
- Requirement of mammalian DNA polymerase-β in base-excision repair
Authors: Robert W. Sobol, Julie K. Horton, Ralf Kühn, Hua Gu, Rakesh Kumar Singhal, Rajendra Prasad, Klaus Rajewsky, Samuel H. Wilson - Nature 1996 cited by 832
- Precise CRISPR-Cas–mediated gene repair with minimal off-target and unintended on-target mutations in human hematopoietic stem cells
Authors: Ngoc Tung Tran, Eric Danner, Xun Li, Robin Graf, Mikhail Lebedin, Kathrin de la Rosa, Ralf Kühn, Klaus Rajewsky, Van Trung Chu - Science Advances 2022 cited by 46
- Inducible gene deletion in astroglia and radial glia—A valuable tool for functional and lineage analysis
Authors: Tetsuji Mori, Kohichi Tanaka, Annalisa Buffo, Wolfgang Wurst, Ralf Kühn, Magdalena Götz - Glia 2006 cited by 416
- MHC Class I Expression in Mice Lacking the Proteasome Subunit LMP-7
Authors: Hans Jörg Fehling, Wojciech Swat, Catherine Laplace, Ralf Kühn, Klaus Rajewsky, Urs Müller, Harald von Boehmer - Science 1994 cited by 528
