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Ralph A. DeFronzo

Active 1973–2025

Also published as
RALPH A. DeFRONZO
364
Papers
111,738
Citations
166
h-index
356
i10-index

Citations

Citations per year for Ralph A. DeFronzo1974: 4 citations1975: 6 citations1976: 9 citations1977: 2 citations1978: 25 citations1979: 29 citations1980: 43 citations1981: 49 citations1982: 44 citations1983: 81 citations1984: 91 citations1985: 128 citations1986: 96 citations1987: 157 citations1988: 173 citations1989: 170 citations1990: 211 citations1991: 245 citations1992: 257 citations1993: 254 citations1994: 290 citations1995: 284 citations1996: 305 citations1997: 302 citations1998: 350 citations1999: 341 citations2000: 447 citations2001: 497 citations2002: 540 citations2003: 607 citations2004: 795 citations2005: 708 citations2006: 830 citations2007: 810 citations2008: 938 citations2009: 984 citations2010: 987 citations2011: 948 citations2012: 885 citations2013: 932 citations2014: 850 citations2015: 879 citations2016: 829 citations2017: 902 citations2018: 790 citations2019: 2,621 citations2020: 2,708 citations2021: 2,379 citations2022: 2,142 citations2023: 1,511 citations2024: 2,586 citations2025: 1,272 citations2026: 62 citations

Citation sources

Countries

World map of the countries and regions citing this authorUnited States: 9,564 citing papers, 27.3% of this breakdownChina: 2,928 citing papers, 8.3% of this breakdownUnited Kingdom: 2,276 citing papers, 6.5% of this breakdownItaly: 1,917 citing papers, 5.5% of this breakdownCanada: 1,414 citing papers, 4% of this breakdownGermany: 1,304 citing papers, 3.7% of this breakdownAustralia: 1,153 citing papers, 3.3% of this breakdownJapan: 1,044 citing papers, 3% of this breakdownSweden: 953 citing papers, 2.7% of this breakdownDenmark: 898 citing papers, 2.6% of this breakdownFrance: 832 citing papers, 2.4% of this breakdownSpain: 769 citing papers, 2.2% of this breakdown
0%27.3%Other 28.5%

Institutions

Fields

  • Medicine70.7%
  • Biochemistry, Genetics and Molecular Biology20.8%
  • Neuroscience2.5%
  • Nursing1.7%
  • Agricultural and Biological Sciences0.7%
  • Immunology and Microbiology0.5%
  • Other3.1%

Topics

  • Diabetes Treatment and Management6.3%
  • Metabolism, Diabetes, and Cancer5.7%
  • Adipose Tissue and Metabolism5.2%
  • Pancreatic function and diabetes4.7%
  • Diabetes, Cardiovascular Risks, and Lipoproteins4.5%
  • Diet and metabolism studies3.6%
  • Other70%

Coauthors

All papers

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  1. Type 2 diabetes mellitus

    Authors: Ralph A. DeFronzo, Ele Ferrannini, Leif Groop, Robert R. Henry, William H. Herman, Jens J. Holst, Frank B. Hu, C. Ronald Kahn, Itamar Raz, Gerald I. Shulman, Donald C. Simonson, Marcia A. Testa, Ram Weiss - Nature Reviews Disease Primers 2015 cited by 2,547

  2. Efficacy of Liraglutide for Weight Loss Among Patients With Type 2 Diabetes

    Authors: Melanie J. Davies, Richard M. Bergenstal, Bruce W. Bode, Robert F. Kushner, Andrew Lewin, Trine Vang Skjøth, Arne Haahr Andreasen, Christine B. Jensen, Ralph A. DeFronzo, for the NN8022-1922 Study Group - JAMA 2015 cited by 1,138

  3. Insulin sensitivity indices obtained from oral glucose tolerance testing: comparison with the euglycemic insulin clamp.

    Authors: Masafumi Matsuda, Ralph A. DeFronzo - Diabetes Care 1999 cited by 5,647

  4. Skeletal Muscle Insulin Resistance Is the Primary Defect in Type 2 Diabetes

    Authors: Ralph A. DeFronzo, Devjit Tripathy - Diabetes Care 2009 cited by 2,081

  5. From the Triumvirate to the Ominous Octet: A New Paradigm for the Treatment of Type 2 Diabetes Mellitus

    Authors: Ralph A. DeFronzo - Diabetes 2009 cited by 2,999

  6. Pathophysiology of diabetic kidney disease: impact of SGLT2 inhibitors

    Authors: Ralph A. DeFronzo, William Reeves, Alaa S. Awad - Nature Reviews Nephrology 2021 cited by 563

  7. A Placebo-Controlled Trial of Pioglitazone in Subjects with Nonalcoholic Steatohepatitis

    Authors: Renata Belfort, Stephen A. Harrison, Kenneth Brown, Celia Darland, Joan Finch, Jean Hardies, Bogdan Balas, Amalia Gastaldelli, Fermin O. Tio, Joseph P. Pulcini, Rachele Berria, Z. Jennie, Sunil Kumar Dwivedi, Russell Havranek, Chris Fincke, Ralph A. DeFronzo, George A. Bannayan, Steven Schenker, Kenneth Cusi - New England Journal of Medicine 2006 cited by 1,811

  8. American Association of Clinical Endocrinology Clinical Practice Guideline: Developing a Diabetes Mellitus Comprehensive Care Plan—2022 Update

    Authors: Lawrence Blonde, Guillermo E. Umpierrez, Sarah Reddy, Janet B. McGill, Sarah L. Berga, Michael A. Bush, Suchitra Chandrasekaran, Ralph A. DeFronzo, Daniel Einhorn, Rodolfo J. Galindo, Thomas W. Gardner, Rajesh Garg, W. Timothy Garvey, Irl B. Hirsch, Daniel L. Hurley, Kenneth Izuora, Mikhail Kosiborod, Darin E. Olson, Shailendra B. Patel, Rodica Pop‐Busui, Archana Sadhu, Susan L. Samson, Carla Stec, William V. Tamborlane, Katherine R. Tuttle, Christine Twining, Adrian Vella, Priyathama Vellanki, Sandra Weber - Endocrine Practice 2022 cited by 469

  9. Insulin Resistance and Atherosclerosis: Implications for Insulin-Sensitizing Agents

    Authors: Antonino Di Pino, Ralph A. DeFronzo - Endocrine Reviews 2019 cited by 545

  10. Insulin: The master regulator of glucose metabolism

    Authors: Luke Norton, Chris E. Shannon, Amalia Gastaldelli, Ralph A. DeFronzo - Metabolism 2022 cited by 310

  11. Insulin resistance, lipotoxicity, type 2 diabetes and atherosclerosis: the missing links. The Claude Bernard Lecture 2009

    Authors: Ralph A. DeFronzo - Diabetologia 2010 cited by 881

  12. The Effect of Insulin on the Disposal of Intravenous Glucose: Results from Indirect Calorimetry and Hepatic and Femoral Venous Catheterization

    Authors: Ralph A. DeFronzo, E Jacot, E Jéquier, E. Maeder, J. Wahren, J. P. Felber - Diabetes 1981 cited by 1,777

  13. Dapagliflozin improves muscle insulin sensitivity but enhances endogenous glucose production

    Authors: Aurora Merovci, Carolina Solis‐Herrera, Giuseppe Daniele, Roy Eldor, Teresa Vanessa Fiorentino, Devjit Tripathy, Juan Xiong, Zandra Perez, Luke Norton, Muhammad Abdul‐Ghani, Ralph A. DeFronzo - Journal of Clinical Investigation 2014 cited by 780

  14. Metformin-associated lactic acidosis: Current perspectives on causes and risk

    Authors: Ralph A. DeFronzo, G. Alexander Fleming, Kim Chen, Thomas A. Bicsak - Metabolism 2015 cited by 644

  15. Pathogenesis of type 2 diabetes mellitus

    Authors: Ralph A. DeFronzo - Medical Clinics of North America 2004 cited by 1,329

  16. Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1

    Authors: Mary‐Elizabeth Patti, Atul J. Butte, Sarah Crunkhorn, Kenneth Cusi, Rachele Berria, Sangeeta Kashyap, Yoshinori Miyazaki, Isaac S. Kohane, Maura Costello, Robert Saccone, Edwin J. Landaker, Allison B. Goldfine, Edward C. Mun, Ralph A. DeFronzo, Jean Finlayson, C. Ronald Kahn, Lawrence J. Mandarino - National Academy of Sciences, Proceedings of the National Academy of Sciences 2003 cited by 1,941

  17. Non-Alcoholic Fatty Liver Disease (NAFLD) and Its Connection with Insulin Resistance, Dyslipidemia, Atherosclerosis and Coronary Heart Disease

    Authors: Melania Gaggini, Mariangela Morelli, E. Buzzigoli, Ralph A. DeFronzo, Elisabetta Bugianesi, Amalia Gastaldelli - Nutrients 2013 cited by 823

  18. Plasma Ceramides Are Elevated in Obese Subjects With Type 2 Diabetes and Correlate With the Severity of Insulin Resistance

    Authors: Jacob M. Haus, Sangeeta R. Kashyap, Takhar Kasumov, Renliang Zhang, Karen R. Kelly, Ralph A. DeFronzo, John P. Kirwan - Diabetes 2008 cited by 668

  19. Insulin Resistance: A Multifaceted Syndrome Responsible for NIDDM, Obesity, Hypertension, Dyslipidemia, and Atherosclerotic Cardiovascular Disease

    Authors: Ralph A. DeFronzo, Eleuterio Ferrannini - Diabetes Care 1991 cited by 4,552

  20. Renal, metabolic and cardiovascular considerations of SGLT2 inhibition

    Authors: Ralph A. DeFronzo, Luke Norton, Muhammad Abdul‐Ghani - Nature Reviews Nephrology 2016 cited by 549

  21. Glucagon-like Peptide-1 and the Central/Peripheral Nervous System: Crosstalk in Diabetes

    Authors: Giovanna Muscogiuri, Ralph A. DeFronzo, Amalia Gastaldelli, Jens J. Holst - Trends in Endocrinology and Metabolism 2016 cited by 166

  22. Effects of Exenatide (Exendin-4) on Glycemic Control and Weight Over 30 Weeks in Metformin-Treated Patients With Type 2 Diabetes

    Authors: Ralph A. DeFronzo, Robert E. Ratner, Jenny Han, Dennis Dong Hwan Kim, Mark Fineman, Alain Baron - Diabetes Care 2005 cited by 1,560

  23. Consensus Statement by the American Association of Clinical Endocrinologists and American College of Endocrinology on the Comprehensive Type 2 Diabetes Management Algorithm – 2020 Executive Summary

    Authors: Alan J. Garber, Yehuda Handelsman, George Grunberger, Daniel Einhorn, Martin J. Abrahamson, Joshua I. Barzilay, Lawrence Blonde, Michael A. Bush, Ralph A. DeFronzo, Jeffrey R. Garber, W. Timothy Garvey, Irl B. Hirsch, Paul S. Jellinger, Janet B. McGill, Jeffrey I. Mechanick, Leigh Perreault, Paul D. Rosenblit, Susan L. Samson, Guillermo E. Umpierrez - Endocrine Practice 2020 cited by 603

  24. Contributions of β-Cell Dysfunction and Insulin Resistance to the Pathogenesis of Impaired Glucose Tolerance and Impaired Fasting Glucose

    Authors: Muhammad Abdul-Ghani, Devjit Tripathy, Ralph A. DeFronzo - Diabetes Care 2006 cited by 743