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Reinhard Lührmann

Active 1982–2025

179
Papers
37,624
Citations
113
h-index
178
i10-index

Citations

Citations per year for Reinhard Lührmann1983: 2 citations1984: 17 citations1985: 40 citations1986: 75 citations1987: 77 citations1988: 85 citations1989: 61 citations1990: 91 citations1991: 88 citations1992: 96 citations1993: 106 citations1994: 132 citations1995: 106 citations1996: 182 citations1997: 182 citations1998: 272 citations1999: 398 citations2000: 266 citations2001: 348 citations2002: 425 citations2003: 330 citations2004: 422 citations2005: 402 citations2006: 405 citations2007: 367 citations2008: 410 citations2009: 336 citations2010: 461 citations2011: 310 citations2012: 417 citations2013: 325 citations2014: 307 citations2015: 306 citations2016: 399 citations2017: 367 citations2018: 319 citations2019: 935 citations2020: 795 citations2021: 838 citations2022: 550 citations2023: 439 citations2024: 698 citations2025: 324 citations2026: 12 citations

Citation sources

Countries

World map of the countries and regions citing this authorUnited States: 3,552 citing papers, 34% of this breakdownGermany: 1,225 citing papers, 11.7% of this breakdownChina: 807 citing papers, 7.7% of this breakdownUnited Kingdom: 742 citing papers, 7.1% of this breakdownFrance: 505 citing papers, 4.8% of this breakdownCanada: 356 citing papers, 3.4% of this breakdownJapan: 351 citing papers, 3.4% of this breakdownSwitzerland: 305 citing papers, 2.9% of this breakdownSpain: 217 citing papers, 2.1% of this breakdownItaly: 203 citing papers, 1.9% of this breakdownNetherlands: 193 citing papers, 1.9% of this breakdownAustralia: 177 citing papers, 1.7% of this breakdown
0%34%Other 17.4%

Institutions

Fields

  • Biochemistry, Genetics and Molecular Biology82%
  • Medicine9.2%
  • Agricultural and Biological Sciences2.7%
  • Immunology and Microbiology2.7%
  • Chemistry1%
  • Neuroscience0.8%
  • Other1.6%

Topics

  • RNA Research and Splicing19.7%
  • RNA modifications and cancer13.7%
  • RNA and protein synthesis mechanisms12%
  • Nuclear Structure and Function3%
  • RNA Interference and Gene Delivery2.6%
  • RNA regulation and disease2.4%
  • Other46.6%

Coauthors

All papers

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  1. Spliceosome Structure and Function

    Authors: C. L. Will, Reinhard Lührmann - Cold Spring Harbor Perspectives in Biology 2010 cited by 1,836

  2. The Spliceosome: Design Principles of a Dynamic RNP Machine

    Authors: M.C. Wahl, Cindy L. Will, Reinhard Lührmann - Cell 2009 cited by 2,704

  3. GraFix: sample preparation for single-particle electron cryomicroscopy

    Authors: Berthold Kastner, N. Fischer, Monika M. Golas, Bjoern Sander, Prakash Dube, Daniel Boehringer, Klaus Hartmuth, Jochen Deckert, Florian Hauer, Elmar Wolf, Hannes Uchtenhagen, Henning Urlaub, Franz Herzog, Jan Peters, Dietmar Poerschke, Reinhard Lührmann, Holger Stark - Nature Methods 2007 cited by 604

  4. Structural Insights into Nuclear pre-mRNA Splicing in Higher Eukaryotes

    Authors: Berthold Kastner, Cindy L. Will, Holger Stark, Reinhard Lührmann - Cold Spring Harbor Perspectives in Biology 2019 cited by 250

  5. Post-transcriptional spliceosomes are retained in nuclear speckles until splicing completion

    Authors: Cyrille Girard, Cindy L. Will, Jianhe Peng, Evgeny M. Makarov, Berthold Kastner, Ira Lemm, Henning Urlaub, Klaus Hartmuth, Reinhard Lührmann - Nature Communications 2012 cited by 296

  6. Structural Basis of Splicing Modulation by Antitumor Macrolide Compounds

    Authors: Constantin Cretu, Anant A. Agrawal, Andrew S. Cook, Cindy L. Will, Peter Fekkes, Peter G. Smith, Reinhard Lührmann, Nicholas Larsen, Silvia Buonamici, Vladimir Peña - Molecular Cell 2018 cited by 176

  7. Molecular architecture of the human 17S U2 snRNP

    Authors: Zhenwei Zhang, Cindy L. Will, Karl Bertram, Olexandr Dybkov, Klaus Hartmuth, Dmitry E. Agafonov, Romina Hofele, Henning Urlaub, Berthold Kastner, Reinhard Lührmann, Holger Stark - Nature 2020 cited by 112

  8. Molecular Architecture of SF3b and Structural Consequences of Its Cancer-Related Mutations

    Authors: Constantin Cretu, Jana Schmitzová, Almudena Ponce-Salvatierra, Olexandr Dybkov, Evelina Ines De Laurentiis, Kundan Sharma, Cindy L. Will, Henning Urlaub, Reinhard Lührmann, Vladimir Peña - Molecular Cell 2016 cited by 252

  9. Disrupted alternative splicing for genes implicated in splicing and ciliogenesis causes PRPF31 retinitis pigmentosa

    Authors: Adriana Buskin, Lili Zhu, Valeria Chichagova, Basudha Basu, Sina Mozaffari‐Jovin, David Dolan, Alastair Droop, Joseph Collin, Revital Bronstein, Sudeep Mehrotra, Michael H. Farkas, Gerrit Hilgen, Kathryn White, Kuan‐Ting Pan, Achim Treumann, Dean Hallam, Katarzyna Bialas, Git Chung, Carla Mellough, Yuchun Ding, Natalio Krasnogor, Stefan Przyborski, Simon Zwolinski, Jumana Y. Al‐Aama, Sameer Alharthi, Yaobo Xu, Gabrielle Wheway, Katarzyna Szymańska, Martin McKibbin, Chris F. Inglehearn, David J. Elliott, Susan Lindsay, Robin R. Ali, David Steel, Lyle Armstrong, Evelyne Sernagor, Henning Urlaub, Eric A. Pierce, Reinhard Lührmann, Sushma-Nagaraja Grellscheid, Colin A. Johnson, Majlinda Lako - Nature Communications 2018 cited by 238

  10. Dynamic Protein-Protein Interaction Wiring of the Human Spliceosome

    Authors: Anna Hegele, Atanas Kamburov, Arndt Großmann, Chrysovalantis Sourlis, Sylvia J. Wowro, Mareike Weimann, Cindy L. Will, Vlad Peña, Reinhard Lührmann, Ulrich Stelzl - Molecular Cell 2012 cited by 431

  11. Single-Stranded Antisense siRNAs Guide Target RNA Cleavage in RNAi

    Authors: Javier Martı̂nez, Agnieszka Patkaniowska, Henning Urlaub, Reinhard Lührmann, Thomas Tuschl - Cell 2002 cited by 1,448

  12. HSPC117 Is the Essential Subunit of a Human tRNA Splicing Ligase Complex

    Authors: Johannes Popow, Markus Englert, Stefan Weitzer, Alexander Schleiffer, Beata E. Mierzwa, Karl Mechtler, Simon Trowitzsch, Cindy L. Will, Reinhard Lührmann, Dieter Söll, Javier Martı̂nez - Science 2011 cited by 258

  13. Structure and Conformational Dynamics of the Human Spliceosomal Bact Complex

    Authors: David Haselbach, Ilya Komarov, Dmitry E. Agafonov, Klaus Hartmuth, Benjamin Graf, Olexandr Dybkov, Henning Urlaub, Berthold Kastner, Reinhard Lührmann, Holger Stark - Cell 2018 cited by 227

  14. Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation

    Authors: C. Townsend, Majety Naga Leelaram, Dmitry E. Agafonov, Olexandr Dybkov, Cindy L. Will, Karl Bertram, Henning Urlaub, Berthold Kastner, Holger Stark, Reinhard Lührmann - Science 2020 cited by 91

  15. Structural insights into how Prp5 proofreads the pre-mRNA branch site

    Authors: Zhenwei Zhang, Norbert Rigo, Olexandr Dybkov, Jean‐Baptiste Fourmann, Cindy L. Will, Vinay Kumar, Henning Urlaub, Holger Stark, Reinhard Lührmann - Nature 2021 cited by 65

  16. Cryo-EM Structure of a Pre-catalytic Human Spliceosome Primed for Activation

    Authors: Karl Bertram, Dmitry E. Agafonov, Olexandr Dybkov, David Haselbach, Majety Naga Leelaram, Cindy L. Will, Henning Urlaub, Berthold Kastner, Reinhard Lührmann, Holger Stark - Cell 2017 cited by 297

  17. Characterization of novel SF3b and 17S U2 snRNP proteins, including a human Prp5p homologue and an SF3b DEAD-box protein

    Authors: Cindy L. Will, Henning Urlaub, Tilmann Achsel, Marc Gentzel, Matthias Wilm, Reinhard Lührmann - The EMBO Journal 2002 cited by 308

  18. Molecular architecture of the human U4/U6.U5 tri-snRNP

    Authors: Dmitry E. Agafonov, Berthold Kastner, Olexandr Dybkov, Romina Hofele, Wen-Ti Liu, Henning Urlaub, Reinhard Lührmann, Holger Stark - Science 2016 cited by 199

  19. A spliceosome intermediate with loosely associated tri-snRNP accumulates in the absence of Prp28 ATPase activity

    Authors: Carsten Boesler, Norbert Rigo, Maria Anokhina, M.J. Tauchert, Dmitry E. Agafonov, Berthold Kastner, Henning Urlaub, Ralf Ficner, Cindy L. Will, Reinhard Lührmann - Nature Communications 2016 cited by 82

  20. Spliceosomal UsnRNP biogenesis, structure and function

    Authors: Cindy L. Will, Reinhard Lührmann - Current Opinion in Cell Biology 2001 cited by 687

  21. Semiquantitative Proteomic Analysis of the Human Spliceosome via a Novel Two-Dimensional Gel Electrophoresis Method

    Authors: Dmitry E. Agafonov, Jochen Deckert, Elmar Wolf, Peter Odenwälder, Sergey Bessonov, Cindy L. Will, Henning Urlaub, Reinhard Lührmann - Molecular and Cellular Biology 2011 cited by 232

  22. Molecular architecture of the Saccharomyces cerevisiae activated spliceosome

    Authors: Reinhard Rauhut, Patrizia Fabrizio, Olexandr Dybkov, Klaus Hartmuth, Vladimir Peña, Ashwin Chari, Vinay Kumar, Chung‐Tien Lee, Henning Urlaub, Berthold Kastner, Holger Stark, Reinhard Lührmann - Science 2016 cited by 186

  23. Localized Inhibition of Protein Phosphatase 1 by NUAK1 Promotes Spliceosome Activity and Reveals a MYC-Sensitive Feedback Control of Transcription

    Authors: Giacomo Cossa, Isabelle Roeschert, Florian Prinz, Apoorva Baluapuri, Raphael Vidal, Christina Schülein‐Völk, Yun-Chien Chang, Carsten P. Ade, Guido Mastrobuoni, Cyrille Girard, Amit Kumar, Lars Wortmann, Susanne Walz, Reinhard Lührmann, Stefan Kempa, Bernhard Küster, Elmar Wolf, Dominik Mumberg, Martin Eilers - Molecular Cell 2020 cited by 64

  24. Structural insights into the cross-exon to cross-intron spliceosome switch

    Authors: Zhenwei Zhang, Vinay Kumar, Olexandr Dybkov, Cindy L. Will, Jiayun Zhong, Sebastian Ludwig, Henning Urlaub, Berthold Kastner, Holger Stark, Reinhard Lührmann - Nature 2024 cited by 36