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Robert A. Kastelein

Active 1987–2020

61
Papers
43,836
Citations
60
h-index
61
i10-index

Citations

Citations per year for Robert A. Kastelein1984: 1 citations1988: 1 citations1989: 4 citations1990: 2 citations1991: 5 citations1992: 12 citations1993: 10 citations1994: 6 citations1995: 6 citations1996: 3 citations1997: 13 citations1998: 53 citations1999: 106 citations2000: 156 citations2001: 155 citations2002: 269 citations2003: 329 citations2004: 408 citations2005: 446 citations2006: 655 citations2007: 987 citations2008: 1,238 citations2009: 1,218 citations2010: 1,098 citations2011: 960 citations2012: 756 citations2013: 701 citations2014: 523 citations2015: 518 citations2016: 373 citations2017: 470 citations2018: 360 citations2019: 1,037 citations2020: 1,023 citations2021: 988 citations2022: 664 citations2023: 454 citations2024: 679 citations2025: 257 citations2026: 5 citations1985–1987: no citations, so these years are not shown

Citation sources

Countries

World map of the countries and regions citing this authorUnited States: 4,903 citing papers, 30.4% of this breakdownChina: 1,306 citing papers, 8.1% of this breakdownUnited Kingdom: 1,160 citing papers, 7.2% of this breakdownGermany: 1,067 citing papers, 6.6% of this breakdownJapan: 1,014 citing papers, 6.3% of this breakdownItaly: 678 citing papers, 4.2% of this breakdownFrance: 661 citing papers, 4.1% of this breakdownCanada: 527 citing papers, 3.3% of this breakdownNetherlands: 415 citing papers, 2.6% of this breakdownSwitzerland: 409 citing papers, 2.5% of this breakdownAustralia: 397 citing papers, 2.4% of this breakdownBelgium: 257 citing papers, 1.6% of this breakdown
0%30.4%Other 20.7%

Institutions

Fields

  • Immunology and Microbiology51.9%
  • Medicine30.9%
  • Biochemistry, Genetics and Molecular Biology12.2%
  • Neuroscience2%
  • Nursing0.9%
  • Agricultural and Biological Sciences0.7%
  • Other1.4%

Topics

  • Psoriasis: Treatment and Pathogenesis7.2%
  • Immune Cell Function and Interaction7%
  • IL-33, ST2, and ILC Pathways6.3%
  • T-cell and B-cell Immunology5.7%
  • Immune Response and Inflammation5.2%
  • Dermatology and Skin Diseases4.3%
  • Other64.3%

Coauthors

All papers

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  1. IL-33, an Interleukin-1-like Cytokine that Signals via the IL-1 Receptor-Related Protein ST2 and Induces T Helper Type 2-Associated Cytokines

    Authors: Jochen Schmitz, Alexander M. Owyang, Elizabeth R. Oldham, Yaoli Song, Erin Murphy, Terril K. McClanahan, Gérard Zurawski, Mehrdad Moshrefi, Jinzhong Qin, Xiaoxia Li, Daniel M. Gorman, J. Fernando Bazán, Robert A. Kastelein - Immunity 2005 cited by 3,699

  2. IL-23 drives a pathogenic T cell population that induces autoimmune inflammation

    Authors: Claire L. Langrish, Yi Chen, Wendy M. Blumenschein, Jeanine Mattson, Beth Basham, Jonathan D. Sedgwick, Terrill K. McClanahan, Robert A. Kastelein, Daniel J. Cua - The Journal of Experimental Medicine 2005 cited by 4,049

  3. Human epithelial cells trigger dendritic cell–mediated allergic inflammation by producing TSLP

    Authors: Vassili Soumelis, Pedro A. Reche, Holger Kanzler, Wei Yuan, G Kasili Edward, Bernhard Homey, Michel Gilliet, Steve Ho, S. V. Antonenko, Annti Lauerma, Kathleen M. Smith, Daniel M. Gorman, Sandra Zurawski, Jon Abrams, Satish Menon, Terri McClanahan, René de Waal Malefyt, Fernando Bazán, Robert A. Kastelein, Yong-Jun Liu - Nature Immunology 2002 cited by 2,147

  4. Novel p19 Protein Engages IL-12p40 to Form a Cytokine, IL-23, with Biological Activities Similar as Well as Distinct from IL-12

    Authors: Birgit Oppmann, Robin Lesley, Bianca Blom, Jackie C. Timans, Yuming Xu, Brisdell Hunte, Félix V. Vega, Nancy Yu, Jing Wang, Komal Singh, Francesca Zonin, Elena Vaisberg, Tatyana Churakova, Man-Ru Liu, Daniel M. Gorman, Janet Wagner, Sandra Zurawski, Yong‐Jun Liu, John S. Abrams, Kevin W. Moore, D Rennick, René de Waal Malefyt, Charles Hannum, J. Fernando Bazán, Robert A. Kastelein - Immunity 2000 cited by 2,807

  5. Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain

    Authors: Daniel J. Cua, Jonathan Sherlock, Yi Chen, Craig A. Murphy, Barbara Joyce, Brian W. P. Seymour, Linda Lucian, Wayne To, Sylvia Kwan, Tatyana Churakova, Sandra Zurawski, Maria Wiekowski, Sérgio A. Lira, Daniel M. Gorman, Robert A. Kastelein, Jonathon D. Sedgwick - Nature 2003 cited by 2,903

  6. IL-23 induces spondyloarthropathy by acting on ROR-γt+ CD3+CD4−CD8− entheseal resident T cells

    Authors: Jonathan Sherlock, Barbara Joyce-Shaikh, Scott Turner, Cheng‐Chi Chao, Manjiri Sathe, Jeff Grein, Daniel M. Gorman, Edward P. Bowman, Terrill K. McClanahan, Jennifer H. Yearley, Gérard Eberl, Christopher D. Buckley, Robert A. Kastelein, Robert H. Pierce, Drake LaFace, Daniel J Cua - Nature Medicine 2012 cited by 1,041

  7. IL-27, a Heterodimeric Cytokine Composed of EBI3 and p28 Protein, Induces Proliferation of Naive CD4+ T Cells

    Authors: Stefan Pflanz, Jackie C. Timans, Jeanne Cheung, Rency Rosales, Holger Kanzler, Jonathan B. Gilbert, Linda Hibbert, Tatyana Churakova, Marilyn Travis, Elena Vaisberg, Wendy M. Blumenschein, Jeanine Mattson, Janet Wagner, Wayne To, Sandra Zurawski, Terrill K. McClanahan, Daniel M. Gorman, J. Fernando Bazán, René de Waal Malefyt, D Rennick, Robert A. Kastelein - Immunity 2002 cited by 1,465

  8. A Receptor for the Heterodimeric Cytokine IL-23 Is Composed of IL-12Rβ1 and a Novel Cytokine Receptor Subunit, IL-23R

    Authors: Christi Parham, Madaline Chirica, Jacqueline Timans, Elena Vaisberg, Marilyn Travis, Jeanne Cheung, Stefan Pflanz, Rebecca Zhang, Komal Singh, Félix V. Vega, Wayne To, Janet Wagner, Anne-Marie O’Farrell, Terrill K. McClanahan, Sandra Zurawski, Charles Hannum, Daniel M. Gorman, D Rennick, Robert A. Kastelein, René de Waal Malefyt, Kevin W. Moore - The Journal of Immunology 2002 cited by 1,290

  9. Development, cytokine profile and function of human interleukin 17–producing helper T cells

    Authors: Nicholas J. Wilson, Katia Boniface, Jason R. Chan, Brent S. McKenzie, Wendy M. Blumenschein, Jeanine Mattson, Beth Basham, Kathleen M. Smith, Taiying Chen, Franck Morel, Jean‐Claude Lecron, Robert A. Kastelein, Daniel J Cua, Terrill K. McClanahan, Edward P. Bowman, René de Waal Malefyt - Nature Immunology 2007 cited by 2,011

  10. IL-23 is essential for T cell–mediated colitis and promotes inflammation via IL-17 and IL-6

    Authors: David Yen, Jeanne Cheung, Heleen Scheerens, Frederique M. Poulet, Terrill K. McClanahan, Brent S. McKenzie, Melanie A. Kleinschek, Alex M. Owyang, Jeanine Mattson, Wendy M. Blumenschein, Erin Murphy, Manjiri Sathe, Daniel J. Cua, Robert A. Kastelein, D Rennick - Journal of Clinical Investigation 2006 cited by 1,527

  11. IL-23 stimulates epidermal hyperplasia via TNF and IL-20R2–dependent mechanisms with implications for psoriasis pathogenesis

    Authors: Jason R. Chan, Wendy M. Blumenschein, Erin Murphy, Caroline Diveu, Maria Wiekowski, Susan J. Abbondanzo, Linda Lucian, Richard Geissler, Scott J. Brodie, Alexa B. Kimball, Daniel M. Gorman, Kathleen M. Smith, René de Waal Malefyt, Robert A. Kastelein, Terrill K. McClanahan, Edward P. Bowman - The Journal of Experimental Medicine 2006 cited by 673

  12. IL-23 promotes tumour incidence and growth

    Authors: John L. Langowski, Xueqing Zhang, Lingling Wu, Jeanine Mattson, Taiying Chen, Kathy L. Smith, Beth Basham, Terrill K. McClanahan, Robert A. Kastelein, Martin Oft - Nature 2006 cited by 1,006

  13. A family of human receptors structurally related to Drosophila Toll

    Authors: Fernando Rock, Gary Hardiman, Jackie C. Timans, Robert A. Kastelein, J. Fernando Bazán - National Academy of Sciences, Proceedings of the National Academy of Sciences 1998 cited by 1,729

  14. Divergent Pro- and Antiinflammatory Roles for IL-23 and IL-12 in Joint Autoimmune Inflammation

    Authors: Craig A. Murphy, Claire L. Langrish, Yi Chen, Wendy M. Blumenschein, Terrill K. McClanahan, Robert A. Kastelein, Jonathon D. Sedgwick, Daniel J. Cua - The Journal of Experimental Medicine 2003 cited by 1,638

  15. The IL-12 Family of Heterodimeric Cytokines

    Authors: Giorgio Trinchieri, Stefan Pflanz, Robert A. Kastelein - Immunity 2003 cited by 920

  16. WSX-1 and Glycoprotein 130 Constitute a Signal-Transducing Receptor for IL-27

    Authors: Stefan Pflanz, Linda Hibbert, Jeanine Mattson, Rency Rosales, Elena Vaisberg, J. Fernando Bazán, Joseph H. Phillips, Terrill K. McClanahan, René de Waal Malefyt, Robert A. Kastelein - The Journal of Immunology 2004 cited by 697

  17. Discovery and Biology of IL-23 and IL-27: Related but Functionally Distinct Regulators of Inflammation

    Authors: Robert A. Kastelein, Christopher A. Hunter, Daniel J. Cua - Annual Review of Immunology 2006 cited by 760

  18. Prostaglandin E2 regulates Th17 cell differentiation and function through cyclic AMP and EP2/EP4 receptor signaling

    Authors: Katia Boniface, Kristian Sass Bak‐Jensen, Ying Li, Wendy M. Blumenschein, Mandy J. McGeachy, Terrill K. McClanahan, Brent S. McKenzie, Robert A. Kastelein, Daniel J. Cua, René de Waal Malefyt - The Journal of Experimental Medicine 2009 cited by 475

  19. Understanding the IL-23–IL-17 immune pathway

    Authors: Brent S. McKenzie, Robert A. Kastelein, Daniel J. Cua - Trends in Immunology 2005 cited by 768

  20. IL-25 regulates Th17 function in autoimmune inflammation

    Authors: Melanie A. Kleinschek, Alexander M. Owyang, Barbara Joyce-Shaikh, Claire L. Langrish, Yi Chen, Daniel M. Gorman, Wendy M. Blumenschein, Terrill K. McClanahan, Frank Brombacher, Stephen D. Hurst, Robert A. Kastelein, Daniel J. Cua - The Journal of Experimental Medicine 2007 cited by 396

  21. Subsets of Human Dendritic Cell Precursors Express Different Toll-like Receptors and Respond to Different Microbial Antigens

    Authors: Norimitsu Kadowaki, Stephen Ho, S. V. Antonenko, René de Waal Malefyt, Robert A. Kastelein, Fernando Bazán, Yong-Jun Liu - The Journal of Experimental Medicine 2001 cited by 1,937

  22. IL‐23 and the Th17 pathway promote inflammation and impair antifungal immune resistance

    Authors: Teresa Zelante, Antonella De Luca, Pierluigi Bonifazi, Claudia Montagnoli, Silvia Bozza, Silvia Moretti, Maria Laura Belladonna, Carmine Vacca, Carmela Conte, Paolo Mosci, Francesco Bistoni, Paolo Puccetti, Robert A. Kastelein, Manfred Köpf, Luigina Romani - European Journal of Immunology 2007 cited by 551

  23. Circulating and gut-resident human Th17 cells express CD161 and promote intestinal inflammation

    Authors: Melanie A. Kleinschek, Katia Boniface, Svetlana Sadekova, Jeff Grein, Erin E. Murphy, Scott Turner, Lisa A. Raskin, Bela Desai, William A. Faubion, René de Waal Malefyt, Robert H. Pierce, Terrill K. McClanahan, Robert A. Kastelein - The Journal of Experimental Medicine 2009 cited by 456

  24. Interleukin 25 regulates type 2 cytokine-dependent immunity and limits chronic inflammation in the gastrointestinal tract

    Authors: Alexander M. Owyang, Colby Zaph, Emma H. Wilson, Katherine J. Guild, Terrill K. McClanahan, H. R. P. Miller, Daniel J. Cua, Michael H. Goldschmidt, Christopher A. Hunter, Robert A. Kastelein, David Artis - The Journal of Experimental Medicine 2006 cited by 389