Ronald Melki
Active 1987–2025
- 120
- Papers
- 19,303
- Citations
- 76
- h-index
- 112
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Medicine49.8%
- Biochemistry, Genetics and Molecular Biology34.4%
- Neuroscience10.9%
- Immunology and Microbiology1%
- Materials Science0.8%
- Environmental Science0.7%
- Other2.4%
Topics
- Parkinson's Disease Mechanisms and Treatments13.2%
- Alzheimer's disease research and treatments8.9%
- Neurological disorders and treatments4.2%
- Neuroinflammation and Neurodegeneration Mechanisms3.3%
- Neurological diseases and metabolism2.7%
- Prion Diseases and Protein Misfolding2.6%
- Other65.1%
Coauthors
- Luc Bousset55
- Laura Pieri13
- Alexis Fenyi10
- Karine Madiona10
- Virginie Redeker10
- Patrik Brundin7
- Harm H. Kampinga6
- Amulya Nidhi Shrivastava5
- Antoine Triller5
- Audrey Coens5
- Dominique Pantaloni5
- Jimmy Savistchenko5
- Leonidas Stefanis5
- Tracy Bellande5
- Veerle Baekelandt5
- Aaron D. Gitler4
- Anke Van der Perren4
- Anne S. Wentink4
- Carmen Nussbaum‐Krammer4
- Gregor Bieri4
- Gérard Batelier4
- Jeffrey H. Kordower4
- M F Carlier4
- Marianne Renner4
All papers
- Microglia jointly degrade fibrillar alpha-synuclein cargo by distribution through tunneling nanotubes
Authors: Hannah Scheiblich, Cira Dansokho, Dilek Mercan, Susanne V. Schmidt, Luc Bousset, Lena Wischhof, Frederik Eikens, Alexandru Odainic, Jasper Spitzer, Angelika Griep, Stephanie Schwartz, Daniele Bano, Eicke Latz, Ronald Melki, Michael T. Heneka - Cell 2021 cited by 355
- Direct evidence of Parkinson pathology spread from the gastrointestinal tract to the brain in rats
Authors: Staffan Holmqvist, Oldriska Chutna, Luc Bousset, Patrick Aldrin-Kirk, Wen Li, Tomas Björklund, Zhan‐You Wang, Laurent Roybon, Ronald Melki, Jiayi Li - Acta Neuropathologica 2014 cited by 910
- α-Synuclein strains cause distinct synucleinopathies after local and systemic administration
Authors: Wouter Peelaerts, Luc Bousset, Anke Van der Perren, Anastasiya Moskalyuk, Rocco Pulizzi, Michèle Giugliano, Chris Van den Haute, Ronald Melki, Veerle Baekelandt - Nature 2015 cited by 1,145
- Structural and functional characterization of two alpha-synuclein strains
Authors: Luc Bousset, Laura Pieri, Gemma Ruiz-Arlandis, Julia Gath, Poul Henning Jensen, Birgit Habenstein, Karine Madiona, Vincent Oliéric, Anja Böckmann, Beat H. Meier, Ronald Melki - Nature Communications 2013 cited by 930
- Two new polymorphic structures of human full-length alpha-synuclein fibrils solved by cryo-electron microscopy
Authors: Ricardo Guerrero-Ferreira, Nicholas M. I. Taylor, Ana‐Andreea Arteni, Pratibha Kumari, Daniel Mona, Philippe Ringler, Markus Britschgi, Matthias E. Lauer, Ali Makky, Joeri Verasdonck, Roland Riek, Ronald Melki, Beat H. Meier, Anja Böckmann, Luc Bousset, Henning Stahlberg - eLife 2019 cited by 351
- Tunneling nanotubes spread fibrillar α‐synuclein by intercellular trafficking of lysosomes
Authors: Saïda Abounit, Luc Bousset, Frida Loría, Seng Zhu, Fabrice de Chaumont, Laura Pieri, Jean‐Christophe Olivo‐Marín, Ronald Melki, Chiara Zurzolo - The EMBO Journal 2016 cited by 394
- Microglia rescue neurons from aggregate-induced neuronal dysfunction and death through tunneling nanotubes
Authors: Hannah Scheiblich, Frederik Eikens, Lena Wischhof, Sabine Opitz, Kay Jüngling, Csaba Cserép, Susanne V. Schmidt, Jessica Lambertz, Tracy Bellande, Balázs Pósfai, Charlotte Geck, Jasper Spitzer, Alexandru Odainic, Sergio Castro‐Gomez, Stephanie Schwartz, Ibrahim Boussaad, Rejko Krüger, Enrico Glaab, Donato A. Di Monte, Daniele Bano, Ádám Dénes, Eike Latz, Ronald Melki, Hans-Christian Pape, Michael T. Heneka - Neuron 2024 cited by 171
- The structural differences between patient-derived α-synuclein strains dictate characteristics of Parkinson’s disease, multiple system atrophy and dementia with Lewy bodies
Authors: Anke Van der Perren, Géraldine Gelders, Alexis Fenyi, Luc Bousset, Filipa Brito, Wouter Peelaerts, Chris Van den Haute, Steve Gentleman, Ronald Melki, Veerle Baekelandt - Acta Neuropathologica 2020 cited by 292
- α‐synuclein oligomers and fibrils: a spectrum of species, a spectrum of toxicities
Authors: Parvez Alam, Luc Bousset, Ronald Melki, Daniel E. Otzen - Journal of Neurochemistry 2019 cited by 307
- G51D α‐synuclein mutation causes a novel Parkinsonian–pyramidal syndrome
Authors: Suzanne Lesage, Mathieu Anheim, Franck Letournel, Luc Bousset, Aurélie Honoré, Nelly Rozas, Laura Pieri, Karine Madiona, Alexandra Dürr, Ronald Melki, Christophe Verny, Alexis Brice, for the French Parkinson's Disease Genetics Study Group - Annals of Neurology 2013 cited by 723
- α-Synuclein transfer between neurons and astrocytes indicates that astrocytes play a role in degradation rather than in spreading
Authors: Frida Loría, Jessica Vargas, Luc Bousset, Sylvie Syan, Audrey Salles, Ronald Melki, Chiara Zurzolo - Acta Neuropathologica 2017 cited by 271
- Increased Immune Activation by Pathologic α‐Synuclein in Parkinson's Disease
Authors: Veselin Grozdanov, Luc Bousset, Meike Hoffmeister, Corinna Bliederhaeuser, Christoph A. Meier, Karine Madiona, Laura Pieri, Martin Kiechle, Pamela J. McLean, Jan Kassubek, Christian Behrends, Albert C. Ludolph, Jochen H. Weishaupt, Ronald Melki, Karin M. Danzer - Annals of Neurology 2019 cited by 162
- Tunneling nanotube (TNT)-mediated neuron-to neuron transfer of pathological Tau protein assemblies
Authors: Meryem Tardivel, Séverine Bégard, Luc Bousset, Simon Dujardin, Audrey Coens, Ronald Melki, Luc Buée, Morvane Colin - Acta Neuropathologica Communications 2016 cited by 297
- Microglial NLRP3 Inflammasome Activation upon TLR2 and TLR5 Ligation by Distinct α-Synuclein Assemblies
Authors: Hannah Scheiblich, Luc Bousset, Stephanie Schwartz, Angelika Griep, Eicke Latz, Ronald Melki, Michael T. Heneka - The Journal of Immunology 2021 cited by 121
- LRRK2 modifies α-syn pathology and spread in mouse models and human neurons
Authors: Gregor Bieri, Michel Brahic, Luc Bousset, Julien Couthouis, Nicholas J. Kramer, K. Rosanna, Lisa Nakayama, Marie Monbureau, Erwin B. Defensor, Birgitt Schüle, Mehrdad Shamloo, Ronald Melki, Aaron D. Gitler - Acta Neuropathologica 2019 cited by 193
- Disassembly of Tau fibrils by the human Hsp70 disaggregation machinery generates small seeding-competent species
Authors: Eliana Nachman, Anne S. Wentink, Karine Madiona, Luc Bousset, Panagiotis Katsinelos, Kieren Allinson, Harm H. Kampinga, William A. McEwan, Thomas R. Jahn, Ronald Melki, Axel Mogk, Bernd Bukau, Carmen Nussbaum‐Krammer - Journal of Biological Chemistry 2020 cited by 168
- α-Synuclein propagates from mouse brain to grafted dopaminergic neurons and seeds aggregation in cultured human cells
Authors: Christian Hansen, Élodie Angot, Ann‐Louise Bergström, Jennifer A. Steiner, Laura Pieri, Gesine Paul, Tiago F. Outeiro, Ronald Melki, Pekka Kallunki, Karina Fog, Jiayi Li, Patrik Brundin - Journal of Clinical Investigation 2011 cited by 837
- Endocytic vesicle rupture is a conserved mechanism of cellular invasion by amyloid proteins
Authors: William P. Flavin, Luc Bousset, Zachary C. Green, Yaping Chu, Stratos Skarpathiotis, Michael J. Chaney, Jeffrey H. Kordower, Ronald Melki, Edward M. Campbell - Acta Neuropathologica 2017 cited by 266
- Intranasal administration of α-synuclein preformed fibrils triggers microglial iron deposition in the substantia nigra of Macaca fascicularis
Authors: Jianjun Guo, Feng Yue, Dong‐Yan Song, Luc Bousset, Xin Liang, Jing Tang, Lin Yuan, Wen Li, Ronald Melki, Yong Tang, Piu Chan, Chuang Guo, Jiayi Li - Cell Death and Disease 2021 cited by 71
- Prion-like transmission of protein aggregates in neurodegenerative diseases
Authors: Patrik Brundin, Ronald Melki, Ron R. Kopito - Nature Reviews Molecular Cell Biology 2010 cited by 755
- Alpha‐synuclein transfers from neurons to oligodendrocytes
Authors: Juan F. Reyes, Nolwen L. Rey, Luc Bousset, Ronald Melki, Patrik Brundin, Élodie Angot - Glia 2013 cited by 275
- Alpha-synuclein research: defining strategic moves in the battle against Parkinson’s disease
Authors: Luís M. A. Oliveira, Thomas Gasser, Robert H. Edwards, Markus Zweckstetter, Ronald Melki, Leonidas Stefanis, Hilal A. Lashuel, David Sulzer, Kostas Vekrellis, Glenda M. Halliday, Julianna J. Tomlinson, Michael G. Schlossmacher, Poul Henning Jensen, Julia M. Schulze‐Hentrich, Olaf Rieß, Warren D. Hirst, Omar M. A. El‐Agnaf, Brit Mollenhauer, Peter T. Lansbury, Tiago F. Outeiro - npj Parkinson s Disease 2021 cited by 178
- LAG3 is not expressed in human and murine neurons and does not modulate α‐synucleinopathies
Authors: Marc Emmenegger, Elena De Cecco, Marián Hruška-Plocháň, Timo Eninger, Matthias M. Schneider, Melanie Barth, Elena Tantardini, Pierre De Rossi, Mehtap Bacioglu, Rebekah G. Langston, Alice Kaganovich, Nora Bengoa‐Vergniory, Andrés González-Guerra, Merve Avar, Daniel Heinzer, Regina Reimann, Lisa M. Häsler, Therese W. Herling, Naunehal S. Matharu, Natalie Landeck, Kelvin C. Luk, Ronald Melki, Philipp J. Kahle, Simone Hornemann, Tuomas P. J. Knowles, Mark Cookson, Magdalini Polymenidou, Mathias Jucker, Adriano Aguzzi - EMBO Molecular Medicine 2021 cited by 79
- Propagation of α-Synuclein Strains within Human Reconstructed Neuronal Network
Authors: Simona Gribaudo, Philippe Tixador, Luc Bousset, Alexis Fenyi, Patricia Lino, Ronald Melki, Jean‐Michel Peyrin, Anselme L. Perrier - Stem Cell Reports 2019 cited by 148
