Saadi Khochbin
Active 1989–2024
- 104
- Papers
- 20,805
- Citations
- 85
- h-index
- 103
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Biochemistry, Genetics and Molecular Biology72.5%
- Medicine18.3%
- Immunology and Microbiology2.7%
- Agricultural and Biological Sciences2.6%
- Neuroscience1.3%
- Environmental Science0.9%
- Other1.7%
Topics
- Histone Deacetylase Inhibitors Research8.8%
- Epigenetics and DNA Methylation7.3%
- Protein Degradation and Inhibitors5.8%
- Genomics and Chromatin Dynamics5.4%
- Ubiquitin and proteasome pathways4.7%
- Peptidase Inhibition and Analysis2.7%
- Other65.3%
Coauthors
- Sophie Rousseaux45
- Cécile Caron15
- Sandrine Curtet14
- Florent Chuffart13
- Jérôme Govin11
- Yingming Zhao11
- Emilie Montellier10
- Anne-Laure Vitte9
- Fayçal Boussouar9
- Alexandra Debernardi8
- André Verdel8
- Carlo Petosa8
- Sophie Barral8
- Thierry Buchou8
- Denis Puthier7
- Ekaterina Bourova-Flin7
- Jonathan Gaucher7
- Minoru Yoshida7
- Nicolas Reynoird7
- Patrick Matthias7
- Élisabeth Brambilla7
- Benoît Gilquin6
- Claudie Lemercier6
- Daniel Panne6
All papers
- Identification of 67 Histone Marks and Histone Lysine Crotonylation as a New Type of Histone Modification
Authors: Minjia Tan, Hao Luo, Sangkyu Lee, Fulai Jin, Jeong Soo Yang, Emilie Montellier, Thierry Buchou, Zhongyi Cheng, Sophie Rousseaux, Nisha Rajagopal, Zhike Lu, Zhen Ye, Qin Zhu, Joanna Wysocka, Yang Ye, Saadi Khochbin, Bing Ren, Yingming Zhao - Cell 2011 cited by 1,898
- Ectopic Activation of Germline and Placental Genes Identifies Aggressive Metastasis-Prone Lung Cancers
Authors: Sophie Rousseaux, Alexandra Debernardi, Baptiste Jacquiau, Anne-Laure Vitte, Aurélien Vesin, Hélène Nagy-Mignotte, Denis Moro‐Sibilot, Pierre‐Yves Brichon, Sylvie Lantuéjoul, Pierre Hainaut, Julien Laffaire, Aurélien de Reyniès, David G. Beer, Jean-François Timsit, Christian Brambilla, Élisabeth Brambilla, Saadi Khochbin - Science Translational Medicine 2013 cited by 621
- Lysine 2-hydroxyisobutyrylation is a widely distributed active histone mark
Authors: Lunzhi Dai, Chao Peng, Emilie Montellier, Zhike Lu, Yue Chen, Haruhiko Ishii, Alexandra Debernardi, Thierry Buchou, Sophie Rousseaux, Fulai Jin, Benjamin R. Sabari, Zhiyou Deng, C. David Allis, Bing Ren, Saadi Khochbin, Yingming Zhao - Nature Chemical Biology 2014 cited by 465
- Transcription factor dimerization activates the p300 acetyltransferase
Authors: Esther Ortega, Srinivasan Rengachari, Ziad Ibrahim, Naghmeh Hoghoughi, Jonathan Gaucher, Alex S. Holehouse, Saadi Khochbin, Daniel Panne - Nature 2018 cited by 186
- Dynamic Competing Histone H4 K5K8 Acetylation and Butyrylation Are Hallmarks of Highly Active Gene Promoters
Authors: Afsaneh Goudarzi, Di Zhang, He Huang, Sophie Barral, Oh Kwang Kwon, Shankang Qi, Zhanyun Tang, Thierry Buchou, Anne-Laure Vitte, HE Tie-ming, Zhongyi Cheng, Emilie Montellier, Jonathan Gaucher, Sandrine Curtet, Alexandra Debernardi, Guillaume Charbonnier, Denis Puthier, Carlo Petosa, Daniel Panne, Sophie Rousseaux, R G Roeder, Yingming Zhao, Saadi Khochbin - Molecular Cell 2016 cited by 268
- Structure of p300 in complex with acyl-CoA variants
Authors: Zuzanna Kaczmarska, Esther Ortega, Afsaneh Goudarzi, He Huang, S.‐H. KIM, José Antonio Márquez, Yingming Zhao, Saadi Khochbin, Daniel Panne - Nature Chemical Biology 2016 cited by 173
- HDAC‐6 interacts with and deacetylates tubulin and microtubules in vivo
Authors: Yu Zhang, Na Li, Cécile Caron, Gabriele Matthias, Daniel Heß, Saadi Khochbin, Patrick Matthias - The EMBO Journal 2003 cited by 726
- Structural insights into p300 regulation and acetylation-dependent genome organisation
Authors: Ziad Ibrahim, Tao Wang, Olivier Destaing, Nicola Salvi, Naghmeh Hoghoughi, Clovis Chabert, Alexandra D. Rusu, Jinjun Gao, Leonardo Feletto, Nicolas Reynoird, Thomas Schalch, Yingming Zhao, Martin Blackledge, Saadi Khochbin, Daniel Panne - Nature Communications 2022 cited by 61
- In vivo destabilization of dynamic microtubules by HDAC6‐mediated deacetylation
Authors: Akihisa Matsuyama, Tadahiro Shimazu, Yuko Sumida, Akiko Saito, Yasuhiro Yoshimatsu, Daphné Seigneurin‐Berny, Hiroyuki Osada, Yasuhiko Komatsu, Norikazu Nishino, Saadi Khochbin, Sueharu Horinouchi, Minoru Yoshida - The EMBO Journal 2002 cited by 702
- Mice Lacking Histone Deacetylase 6 Have Hyperacetylated Tubulin but Are Viable and Develop Normally
Authors: Yu Zhang, So-Hee Kwon, Teppei Yamaguchi, Fabien Cubizolles, Sophie Rousseaux, Michaela Kneissel, Chun Cao, Na Li, Hwei-Ling Cheng, Katrin F. Chua, David B. Lombard, Adam Mizeracki, Gabriele Matthias, Frederick W. Alt, Saadi Khochbin, Patrick Matthias - Molecular and Cellular Biology 2008 cited by 555
- Cooperative binding of two acetylation marks on a histone tail by a single bromodomain
Authors: Jeanne Morinière, Sophie Rousseaux, Ulrich Steuerwald, Montserrat Soler‐López, Sandrine Curtet, Anne-Laure Vitte, Jérôme Govin, Jonathan Gaucher, Karin Sadoul, Darren J. Hart, Jeroen Krijgsveld, Saadi Khochbin, Christoph W. Müller, Carlo Petosa - Nature 2009 cited by 473
- HDAC6, at the crossroads between cytoskeleton and cell signaling by acetylation and ubiquitination
Authors: Cyril Boyault, Karin Sadoul, M. Pabion, Saadi Khochbin - Oncogene 2007 cited by 391
- HDAC6 controls major cell response pathways to cytotoxic accumulation of protein aggregates
Authors: Cyril Boyault, Yu Zhang, Sabrina Fritah, Cécile Caron, Benoît Gilquin, So Hee Kwon, Carmen Garrido, Tso‐Pang Yao, Claire Vourc’h, Patrick Matthias, Saadi Khochbin - Genes & Development 2007 cited by 363
- Regulatory cross-talk between lysine acetylation and ubiquitination: role in the control of protein stability
Authors: C�cile Caron, Cyril Boyault, Saadi Khochbin - BioEssays 2005 cited by 299
- Regulation of microtubule dynamics by inhibition of the tubulin deacetylase HDAC6
Authors: Yuliya Zilberman, Christoph Ballestrem, Letizia Carramusa, Ralph Mazitschek, Saadi Khochbin, Alexander D. Bershadsky - Journal of Cell Science 2009 cited by 232
- Pregnancy exposure to atmospheric pollution and meteorological conditions and placental DNA methylation
Authors: Émilie Abraham, Sophie Rousseaux, Lydiane Agier, Lise Giorgis-Allemand, Jörg Tost, Julien Galineau, Agnès Hulin, Valérie Siroux, Daniel Vaiman, Marie‐Aline Charles, Barbara Heude, Anne Forhan, Joel Schwartz, Florent Chuffart, Ekaterina Bourov a-Flin, Saadi Khochbin, Rémy Slama, Johanna Lepeule - Environment International 2018 cited by 133
- Oncogenesis by sequestration of CBP/p300 in transcriptionally inactive hyperacetylated chromatin domains
Authors: Nicolas Reynoird, Brian E. Schwartz, Manuela Delvecchio, Karin Sadoul, David J. Meyers, Chandrani Mukherjee, Cécile Caron, Hiroshi Kimurâ, Sophie Rousseaux, Philip A. Cole, Daniel Panne, Christopher A. French, Saadi Khochbin - The EMBO Journal 2010 cited by 190
- CYLD negatively regulates cell‐cycle progression by inactivating HDAC6 and increasing the levels of acetylated tubulin
Authors: Sara A. Wickström, Katarzyna Chmielarska Masoumi, Saadi Khochbin, Reinhard Fässler, Ramin Massoumi - The EMBO Journal 2009 cited by 174
- Histone Variant H2A.L.2 Guides Transition Protein-Dependent Protamine Assembly in Male Germ Cells
Authors: Sophie Barral, Yuichi Morozumi, Hiroki Tanaka, Emilie Montellier, Jérôme Govin, Maud de Dieuleveult, Guillaume Charbonnier, Yohann Couté, Denis Puthier, Thierry Buchou, Fayçal Boussouar, Takashi Urahama, François Fenaille, Sandrine Curtet, Patrick Héry, Nicolas Fernandez, Hitoshi Shiota, Matthieu Gérard, Sophie Rousseaux, Hitoshi Kurumizaka, Saadi Khochbin - Molecular Cell 2017 cited by 156
- Potent histone deacetylase inhibitors built from trichostatin A and cyclic tetrapeptide antibiotics including trapoxin
Authors: Ryohei Furumai, Yasuhiko Komatsu, Norikazu Nishino, Saadi Khochbin, Minoru Yoshida, Sueharu Horinouchi - National Academy of Sciences, Proceedings of the National Academy of Sciences 2000 cited by 412
- A unified phylogeny-based nomenclature for histone variants
Authors: Paul B. Talbert, Kami Ahmad, Geneviève Almouzni, Juan Ausió, Frédéric Berger, Prem L. Bhalla, William M. Bonner, W. Zacheus Cande, Brian P. Chadwick, Wan Chan, George Cross, Liwang Cui, Stéfan Dimitrov, Detlef Doenecke, José M. Eirín‐López, Martin A. Gorovsky, Sandra B. Hake, Barbara A. Hamkalo, Sarah Holec, Steven E. Jacobsen, Kinga Kamieniarz-Gdula, Saadi Khochbin, Andreas G. Ladurner, David Landsman, John Latham, Benjamin Loppin, Harmit S. Malik, William F. Marzluff, John R. Pehrson, Jan Postberg, Robert J. Schneider, Mohan B. Singh, M. Mitchell Smith, Eric M. Thompson, Maria‐Elena Torres‐Padilla, David J. Tremethick, Bryan M. Turner, Jakob H. Waterborg, Heike Wollmann, Ramesh Yelagandula, Bing Zhu, Steven Henikoff - Epigenetics & Chromatin 2012 cited by 345
- Stress-induced transcription of satellite III repeats
Authors: Caroline Jolly, Alexandra Metz, Jérôme Govin, Marc Vigneron, Bryan M. Turner, Saadi Khochbin, Claire Vourc’h - The Journal of Cell Biology 2003 cited by 322
- Histone lysine methacrylation is a dynamic post-translational modification regulated by HAT1 and SIRT2
Authors: Kyle Delaney, Minjia Tan, Zhesi Zhu, Jinjun Gao, Lunzhi Dai, Sun‐Joo Kim, Jun Ding, Maomao He, Levon Halabelian, Lu Yang, Prabakaran Nagarajan, Mark R. Parthun, Sangkyu Lee, Saadi Khochbin, Y. George Zheng, Yingming Zhao - Cell Discovery 2021 cited by 56
- Metabolically controlled histone H4K5 acylation/acetylation ratio drives BRD4 genomic distribution
Authors: Mengqing Gao, Jin Wang, Sophie Rousseaux, Minjia Tan, Lulu Pan, Lijun Peng, Sisi Wang, Wenqian Xu, Jiayi Ren, Yuanfang Liu, Martin Spinck, Sophie Barral, Tao Wang, Florent Chuffart, Ekaterina Bourov a-Flin, Denis Puthier, Sandrine Curtet, Lisa Bargier, Zhongyi Cheng, Heinz Neumann, Jian Li, Yingming Zhao, Jian‐Qing Mi, Saadi Khochbin - Cell Reports 2021 cited by 48
