Simon W. M. John
Active 1991–2025
- 89
- Papers
- 19,391
- Citations
- 73
- h-index
- 83
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Medicine44.9%
- Neuroscience28.1%
- Biochemistry, Genetics and Molecular Biology20.2%
- Immunology and Microbiology3.9%
- Engineering0.7%
- Nursing0.7%
- Other1.5%
Topics
- Neuroinflammation and Neurodegeneration Mechanisms9.7%
- Glaucoma and retinal disorders7.5%
- Retinal Development and Disorders4.6%
- Retinal Diseases and Treatments4.1%
- Neuroscience and Neuropharmacology Research2.6%
- Neurogenesis and neuroplasticity mechanisms2.1%
- Other69.4%
Coauthors
- Richard S. Smith31
- Richard T. Libby19
- Gareth R. Howell18
- Pete A. Williams14
- Jeffrey M. Harder13
- Michael G. Anderson13
- О. В. Савинова10
- Ileana Soto9
- Krishnakumar Kizhatil9
- Douglas B. Gould8
- K. Saidas Nair8
- Nicholas Tolman8
- Christa Montgomery7
- Abbot F. Clark6
- Adriana Zabaleta6
- Bo Chang6
- Gregory L. Sousa6
- Nicole E. Foxworth6
- Norman L. Hawes6
- Oliver Smithies6
- Revathi Balasubramanian6
- Catherine Braine5
- Danilo G. Macalinao5
- Jeffrey K. Marchant5
All papers
- The Classical Complement Cascade Mediates CNS Synapse Elimination
Authors: Beth Stevens, Nicola J. Allen, Luis E Vazquez, Gareth R. Howell, Karen S. Christopherson, Navid Nouri, Kristina D. Micheva, Adrienne K. Mehalow, Andrew D. Huberman, Benjamin K. Stafford, Alexander Sher, A. M. Litke, John D. Lambris, Stephen J Smith, Simon W. M. John, Ben A. Barres - Cell 2007 cited by 3,370
- Vitamin B 3 modulates mitochondrial vulnerability and prevents glaucoma in aged mice
Authors: Pete A. Williams, Jeffrey M. Harder, Nicole E. Foxworth, Kelly E. Cochran, Vivek M. Philip, Vittorio Porciatti, Oliver Smithies, Simon W. M. John - Science 2017 cited by 642
- Nicotinamide and Pyruvate for Neuroenhancement in Open-Angle Glaucoma
Authors: Carlos Gustavo De Moraes, Simon W. M. John, Pete A. Williams, Dana M. Blumberg, George A. Cioffi, Jeffrey M. Liebmann - JAMA Ophthalmology 2021 cited by 149
- Disturbed glucose and pyruvate metabolism in glaucoma with neuroprotection by pyruvate or rapamycin
Authors: Jeffrey M. Harder, Chelsea Guymer, John Wood, Evangelia Daskalaki, Glyn Chidlow, Chi Zhang, Revathi Balasubramanian, Brynn H. Cardozo, Nicole E. Foxworth, Kelly E. Deering, Tionna B. Ouellette, Christa Montgomery, Craig E. Wheelock, Robert J. Casson, Pete A. Williams, Simon W. M. John - National Academy of Sciences, Proceedings of the National Academy of Sciences 2020 cited by 132
- Role of COL4A1 in Small-Vessel Disease and Hemorrhagic Stroke
Authors: Douglas B. Gould, F. Campbell Phalan, Saskia E. van Mil, John P. Sundberg, Katayoun Vahedi, Pascale Massin, Marie Germaine Bousser, Peter Heutink, Jeffrey H. Miner, Elisabeth Tournier‐Lasserve, Simon W. M. John - New England Journal of Medicine 2006 cited by 575
- Angiopoietin receptor TEK mutations underlie primary congenital glaucoma with variable expressivity
Authors: Tomokazu Souma, Stuart W. Tompson, Benjamin R. Thomson, Owen M. Siggs, Krishnakumar Kizhatil, Shinji Yamaguchi, Liang Feng, Vachiranee Limviphuvadh, Kristina N. Whisenhunt, Sebastian Maurer‐Stroh, Tammy L. Yanovitch, Luba Kalaydjieva, Dimitar N. Azmanov, Simone Finzi, Lucia Mauri, Shahrbanou Javadiyan, Emmanuelle Souzeau, Tiger Zhou, Alex W. Hewitt, Bethany A. Kloss, Kathryn P. Burdon, David A. Mackey, Keri F. Allen, Jonathan B. Ruddle, Sing-Hui Lim, Steve Rozen, Khanh-Nhat Tran-Viet, Xiaorong Liu, Simon W. M. John, Janey L. Wiggs, Francesca Pasutto, Jamie E. Craig, Jing Jin, Susan E. Quaggin, Terri L. Young - Journal of Clinical Investigation 2016 cited by 289
- Axons of retinal ganglion cells are insulted in the optic nerve early in DBA/2J glaucoma
Authors: Gareth R. Howell, Richard T. Libby, Tatjana Jakobs, Richard S. Smith, F. Campbell Phalan, Joseph W. Barter, Jessica M. Barbay, Jeffrey K. Marchant, M. Nagaraju, Vittorio Porciatti, Alan V. Whitmore, Richard H. Masland, Simon W. M. John - The Journal of Cell Biology 2007 cited by 626
- Under Pressure: Cellular and Molecular Responses During Glaucoma, a Common Neurodegeneration with Axonopathy
Authors: Robert W. Nickells, Gareth R. Howell, Ileana Soto, Simon W. M. John - Annual Review of Neuroscience 2012 cited by 347
- Nicotinamide treatment robustly protects from inherited mouse glaucoma
Authors: Pete A. Williams, Jeffrey M. Harder, Brynn H. Cardozo, Nicole E. Foxworth, Simon W. M. John - Communicative & Integrative Biology 2018 cited by 101
- Molecular clustering identifies complement and endothelin induction as early events in a mouse model of glaucoma
Authors: Gareth R. Howell, Danilo G. Macalinao, Gregory L. Sousa, Michael L. Walden, Ileana Soto, Stephen C. Kneeland, Jessica M. Barbay, Benjamin L. King, Jeffrey K. Marchant, Matthew Hibbs, Beth Stevens, Ben A. Barres, Abbot F. Clark, Richard T. Libby, Simon W. M. John - Journal of Clinical Investigation 2011 cited by 499
- Angiopoietin-1 is required for Schlemm’s canal development in mice and humans
Authors: Benjamin R. Thomson, Tomokazu Souma, Stuart W. Tompson, Tuncer Onay, Krishnakumar Kizhatil, Owen M. Siggs, Liang Feng, Kristina N. Whisenhunt, Tammy L. Yanovitch, Luba Kalaydjieva, Dimitar N. Azmanov, Simone Finzi, Christine E. Tanna, Alex W. Hewitt, David A. Mackey, Yasmin S. Bradfield, Emmanuelle Souzeau, Shari Javadiyan, Janey L. Wiggs, Francesca Pasutto, Xiaorong Liu, Simon W. M. John, Jamie E. Craig, Jing Jin, Terri L. Young, Susan E. Quaggin - Journal of Clinical Investigation 2017 cited by 199
- A multiethnic genome-wide association study of primary open-angle glaucoma identifies novel risk loci
Authors: Hélène Choquet, Seyyedhassan Paylakhi, Stephen C. Kneeland, Khanh K. Thai, Thomas J. Hoffmann, Jie Yin, Mark Kvale, Yambazi Banda, Nicholas Tolman, Pete A. Williams, Catherine Schaefer, Ronald B. Melles, Neil Risch, Simon W. M. John, K. Saidas Nair, Eric Jorgenson - Nature Communications 2018 cited by 196
- Chronic consumption of a western diet induces robust glial activation in aging mice and in a mouse model of Alzheimer’s disease
Authors: Leah Graham, Jeffrey M. Harder, Ileana Soto, Wilhelmine N. de Vries, Simon W. M. John, Gareth R. Howell - Scientific Reports 2016 cited by 115
- Mutations in Col4a1 Cause Perinatal Cerebral Hemorrhage and Porencephaly
Authors: Douglas B. Gould, F. Campbell Phalan, Guido J. Breedveld, Saskia E. van Mil, Richard S. Smith, John C. Schimenti, Umberto Aguglia, Marjo S. van der Knaap, Peter Heutink, Simon W. M. John - Science 2005 cited by 537
- Mutations in genes encoding melanosomal proteins cause pigmentary glaucoma in DBA/2J mice
Authors: Michael G. Anderson, Richard S. Smith, Norman L. Hawes, Adriana Zabaleta, Bo Chang, Janey L. Wiggs, Simon W. M. John - Nature Genetics 2001 cited by 467
- Inherited glaucoma in DBA/2J mice: Pertinent disease features for studying the neurodegeneration
Authors: Richard T. Libby, Michael G. Anderson, Iok‐Hou Pang, ZACHARY H. ROBINSON, О. В. Савинова, Ioan M Cosma, Amy Snow, Lawriston A. Wilson, Richard S. Smith, Abbot F. Clark, Simon W. M. John - Visual Neuroscience 2005 cited by 423
- Radiation treatment inhibits monocyte entry into the optic nerve head and prevents neuronal damage in a mouse model of glaucoma
Authors: Gareth R. Howell, Ileana Soto, Xianjun Zhu, Margaret M. Ryan, Danilo G. Macalinao, Gregory L. Sousa, Lura Brianna Caddle, Katharine H. MacNicoll, Jessica M. Barbay, Vittorio Porciatti, Michael G. Anderson, Richard S. Smith, Abbot F. Clark, Richard T. Libby, Simon W. M. John - Journal of Clinical Investigation 2012 cited by 243
- Nicotinamide and WLDS Act Together to Prevent Neurodegeneration in Glaucoma
Authors: Pete A. Williams, Jeffrey M. Harder, Nicole E. Foxworth, Brynn H. Cardozo, Kelly E. Cochran, Simon W. M. John - Frontiers in Neuroscience 2017 cited by 114
- Glaucoma as a Metabolic Optic Neuropathy: Making the Case for Nicotinamide Treatment in Glaucoma
Authors: Pete A. Williams, Jeffrey M. Harder, Simon W. M. John - Journal of Glaucoma 2017 cited by 105
- Inhibition of monocyte-like cell extravasation protects from neurodegeneration in DBA/2J glaucoma
Authors: Pete A. Williams, Catherine Braine, Krishnakumar Kizhatil, Nicole E. Foxworth, Nicholas Tolman, Jeffrey M. Harder, R. Scott, Gregory L. Sousa, Alyssa Panitch, Gareth R. Howell, Simon W. M. John - Molecular Neurodegeneration 2019 cited by 89
- Schlemm's Canal Is a Unique Vessel with a Combination of Blood Vascular and Lymphatic Phenotypes that Forms by a Novel Developmental Process
Authors: Krishnakumar Kizhatil, Margaret M. Ryan, Jeffrey K. Marchant, Stephen E. Henrich, Simon W. M. John - PLoS Biology 2014 cited by 222
- Nonvenous Origin of Dermal Lymphatic Vasculature
Authors: Inés Martínez‐Corral, Maria H. Ulvmar, Lukas Stanczuk, Florence Tatin, Krishnakumar Kizhatil, Simon W. M. John, Kari Alitalo, Sagrario Ortega, Taija Mäkinen - Circulation Research 2015 cited by 254
- Inhibition of the classical pathway of the complement cascade prevents early dendritic and synaptic degeneration in glaucoma
Authors: Pete A. Williams, James R. Tribble, Keating W. Pepper, Stephen D. Cross, B. Paul Morgan, James E. Morgan, Simon W. M. John, Gareth R. Howell - Molecular Neurodegeneration 2016 cited by 182
- Consensus Recommendation for Mouse Models of Ocular Hypertension to Study Aqueous Humor Outflow and Its Mechanisms
Authors: Colleen M McDowell, Krishnakumar Kizhatil, Michael H. Elliott, Darryl R. Overby, Joseph M. Sherwood, J. Cameron Millar, Markus H. Kuehn, Gulab Zode, Ted S. Acott, Michael G. Anderson, Sanjoy K. Bhattacharya, Jacques Bertrand, Terete Borrás, Diane E. Bovenkamp, Lin Cheng, John Danias, Michael L. De Ieso, Yiqin Du, Jennifer A. Faralli, Rudolf Fuchshofer, Preethi S. Ganapathy, Haiyan Gong, Samuel Herberg, Humberto Hernandez, Peter Humphries, Simon W. M. John, Paul L. Kaufman, Kate E. Keller, Mary J. Kelley, Ruth A. Kelly, David Križaj, Ajay Kumar, Brian C. Leonard, Raquel L. Lieberman, Paloma B. Liton, Yutao Liu, Katy C. Liu, Navita N. López, Weiming Mao, Timur Mavlyutov, Fiona McDonnell, Gillian J. McLellan, Philip Mzyk, Andrews Nartey, Louis R. Pasquale, Gaurang Patel, Padmanabhan P. Pattabiraman, Donna M. Peters, Vijaykrishna Raghunathan, Ponugoti Vasantha Rao, Naga Pradeep Rayana, Urmimala Raychaudhuri, Ester Reina‐Torres, Ruiyi Ren, Douglas J. Rhee, Uttio Roy Chowdhury, John R. Samples, E. Griffen Samples, Najam A. Sharif, Joel S. Schuman, Val C. Sheffield, Cooper H. Stevenson, Avinash Soundararajan, Preeti Subramanian, Chenna Kesavulu Sugali, Yang Sun, Carol B. Toris, Karen Y. Torrejon, Amir Vahabikashi, Janice A. Vranka, Ting Wang, Colin E. Willoughby, Xin Chen, Hongmin Yun, Hao F. Zhang, Michael P. Fautsch, Ernst R. Tamm, Abbot F. Clark, C. Ross Ethier, W. Daniel Stamer - Investigative Ophthalmology & Visual Science 2022 cited by 55
