Stefan Somlo
Active 1983–2024
- 94
- Papers
- 20,289
- Citations
- 83
- h-index
- 93
- i10-index
Citations
Citation sources
Countries
Institutions
- Mayo Clinic1.7%
- Harvard University1.7%
- Yale University1.6%
- Inserm0.9%
- Johns Hopkins University0.8%
- Brigham and Women's Hospital0.8%
- Other92.5%
Fields
- Biochemistry, Genetics and Molecular Biology72.5%
- Medicine17.1%
- Neuroscience5.7%
- Psychology1.6%
- Immunology and Microbiology0.9%
- Nursing0.5%
- Other1.7%
Topics
- Genetic and Kidney Cyst Diseases18.3%
- Renal and related cancers10.4%
- Biomedical Research and Pathophysiology3.5%
- Genetic Syndromes and Imprinting3.3%
- Renal Diseases and Glomerulopathies3.1%
- Hedgehog Signaling Pathway Studies2.6%
- Other58.8%
Coauthors
- Yiqiang Cai21
- Xin Tian20
- Gregory G. Germino13
- Vicente E. Torres13
- Peter Igarashi12
- Anna‐Rachel Gallagher11
- Guanqing Wu9
- Lisa M. Guay‐Woodford9
- Luiz F. Onuchic9
- David M. Reynolds8
- Lin Geng8
- Michael J. Caplan8
- Peter C. Harris8
- Qi Qian8
- Sorin V. Fedeles8
- Ke Dong7
- Laszlo Furu7
- Barbara E. Ehrlich6
- Carsten Bergmann6
- Klaus Zerres6
- Ming Ma6
- Tomohito Hayashi6
- Airong Li5
- Ellis D. Avner5
All papers
- Genetics in chronic kidney disease: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference
Authors: Anna Köttgen, Émilie Cornec-Le Gall, Jan Halbritter, Krzysztof Kiryluk, Andrew Mallett, Rulan S. Parekh, Hila Milo Rasouly, Matthew G. Sampson, Adrienne Tin, Corinne Antignac, Elisabet Ars, Carsten Bergmann, Anthony J. Bleyer, Detlef Böckenhauer, Olivier Devuyst, José C. Florez, Kevin Fowler, Nora Franceschini, Masafumi Fukagawa, Daniel P. Gale, Rasheed Gbadegesin, David B. Goldstein, Morgan E. Grams, Anna Greka, Oliver Groß, Lisa M. Guay‐Woodford, Peter C. Harris, Julia Hoefele, Adriana M. Hung, Nine V.A.M. Knoers, Jeffrey B. Kopp, Matthias Kretzler, Matthew B. Lanktree, Beata S. Lipska‐Ziętkiewicz, Kathy Nicholls, Kandai Nozu, Akinlolu Ojo, Afshin Parsa, Cristian Pattaro, York Pei, Martin R. Pollak, Eugene P. Rhee, Simone Sanna‐Cherchi, Judy Savige, John A. Sayer, Francesco Scolari, John R. Sedor, Xueling Sim, Stefan Somlo, Katalin Suszták, Bamidele O. Tayo, Roser Torrá, Albertien M. van Eerde, André Weinstock, Cheryl A. Winkler, Matthias Wuttke, Hong Zhang, Jennifer King, Michael Cheung, Michel Jadoul, Wolfgang C. Winkelmayer, Ali G. Gharavi - Kidney International 2022 cited by 187
- Loss of cilia suppresses cyst growth in genetic models of autosomal dominant polycystic kidney disease
Authors: Ming Ma, Xin Tian, Peter Igarashi, Gregory J. Pazour, Stefan Somlo - Nature Genetics 2013 cited by 360
- Monoallelic Mutations to DNAJB11 Cause Atypical Autosomal-Dominant Polycystic Kidney Disease
Authors: Émilie Cornec-Le Gall, Rory J. Olson, Whitney Besse, Christina M. Heyer, Vladimir G. Gainullin, Jessica M. Smith, Marie‐Pierre Audrézet, Katharina Hopp, Binu Porath, Beili Shi, Saurabh Baheti, Sarah R. Senum, Jennifer Arroyo, Charles D. Madsen, Claude Férec, Dominique Joly, François Jouret, Oussamah Fikri-Benbrahim, Christophe Charasse, Jean-Marie Coulibaly, Alan S.L. Yu, Korosh Khalili, York Pei, Stefan Somlo, Yannick Le Meur, Vicente E. Torres, Peter C. Harris - The American Journal of Human Genetics 2018 cited by 313
- ALG9 Mutation Carriers Develop Kidney and Liver Cysts
Authors: Whitney Besse, Alex R. Chang, Jonathan Z. Luo, William Triffo, Bryn S. Moore, Ashima Gulati, Dustin N. Hartzel, Shrikant Mane, Vicente E. Torres, Stefan Somlo, Tooraj Mirshahi - Journal of the American Society of Nephrology 2019 cited by 158
- Renal plasticity revealed through reversal of polycystic kidney disease in mice
Authors: Ke Dong, Chao Zhang, Xin Tian, Daniel Coman, Fahmeed Hyder, Ming Ma, Stefan Somlo - Nature Genetics 2021 cited by 122
- Cyst formation and activation of the extracellular regulated kinase pathway after kidney specific inactivation of Pkd1
Authors: Sekiya Shibazaki, Zhiheng Yu, Saori Nishio, Xin Tian, R. Brent Thomson, Michihiro Mitobe, Angeliki Louvi, Heino Velázquez, Shuta Ishibe, Lloyd G. Cantley, Peter Igarashi, Stefan Somlo - Human Molecular Genetics 2008 cited by 287
- PKD2 , a Gene for Polycystic Kidney Disease That Encodes an Integral Membrane Protein
Authors: Toshio Mochizuki, Guanqing Wu, Tomohito Hayashi, Stavroulla Xenophontos, Barbera Veldhuisen, Jasper J. Saris, David M. Reynolds, Yiqiang Cai, Patricia A. Gabow, Alkis Pierides, William J. Kimberling, Martijn H. Breuning, Constantinos Deltas, Dorien J.M. Peters, Stefan Somlo - Science 1996 cited by 1,418
- Two Populations of Node Monocilia Initiate Left-Right Asymmetry in the Mouse
Authors: James McGrath, Stefan Somlo, Svetlana Makova, Xin Tian, Martina Brueckner - Cell 2003 cited by 807
- Polycystin-2 is an intracellular calcium release channel
Authors: Peter Koulen, Yiqiang Cai, Lin Geng, Yoshiko Maeda, S. Nishimura, Ralph Witzgall, Barbara E. Ehrlich, Stefan Somlo - Nature Cell Biology 2002 cited by 714
- Collagen IV Gene Mutations in Adults With Bilateral Renal Cysts and CKD
Authors: Ashima Gulati, Ángel Sevillano, Manuel Praga, Eduardo Gutiérrez, I Madrigal de Alba, Neera K. Dahl, Whitney Besse, Jungmin Choi, Stefan Somlo - Kidney International Reports 2019 cited by 61
- Activating AMP-activated protein kinase (AMPK) slows renal cystogenesis
Authors: Vinita Takiar, Saori Nishio, Patricia Seo-Mayer, Jennifer King, Hui Li, Li Zhang, Anil Karihaloo, Kenneth R. Hallows, Stefan Somlo, Michael J. Caplan - National Academy of Sciences, Proceedings of the National Academy of Sciences 2011 cited by 340
- Epithelial-Specific Cre/lox Recombination in the Developing Kidney and Genitourinary Tract
Authors: Xinli Shao, Stefan Somlo, Peter Igarashi - Journal of the American Society of Nephrology 2002 cited by 326
- Macrophages Promote Cyst Growth in Polycystic Kidney Disease
Authors: Anil Karihaloo, Farrukh M. Koraishy, Sarah C. Huen, Yashang Lee, David Merrick, Michael J. Caplan, Stefan Somlo, Lloyd G. Cantley - Journal of the American Society of Nephrology 2011 cited by 234
- Mcp1 Promotes Macrophage-Dependent Cyst Expansion in Autosomal Dominant Polycystic Kidney Disease
Authors: Marcelo Ferreira Cassini, Vijayakumar R. Kakade, Elizabeth Kurtz, Parker L. Sulkowski, Peter M. Glazer, Richard Torres, Stefan Somlo, Lloyd G. Cantley - Journal of the American Society of Nephrology 2018 cited by 112
- PKHD1, the Polycystic Kidney and Hepatic Disease 1 Gene, Encodes a Novel Large Protein Containing Multiple Immunoglobulin-Like Plexin-Transcription–Factor Domains and Parallel Beta-Helix 1 Repeats
Authors: Luiz F. Onuchic, Laszlo Furu, Yasuyuki Nagasawa, Xiaoying Hou, Thomas Eggermann, Zhiyong Ren, Carsten Bergmann, Jan Senderek, Ernie Esquivel, Raoul Zeltner, Sabine Rudnik‐Schöneborn, Michael Mrug, William E. Sweeney, Ellis D. Avner, Klaus Zerres, Lisa M. Guay‐Woodford, Stefan Somlo, Gregory G. Germino - The American Journal of Human Genetics 2002 cited by 510
- Small-Molecule CFTR Inhibitors Slow Cyst Growth in Polycystic Kidney Disease
Authors: Baoxue Yang, Nitin D. Sonawane, Dan Zhao, Stefan Somlo, A. S. Verkman - Journal of the American Society of Nephrology 2008 cited by 218
- Isolated polycystic liver disease genes define effectors of polycystin-1 function
Authors: Whitney Besse, Ke Dong, Jungmin Choi, Sohan Punia, Sorin V. Fedeles, Murim Choi, Anna‐Rachel Gallagher, Emily Huang, Ashima Gulati, James Knight, Shrikant Mane, Esa Tahvanainen, Pia Tahvanainen, Simone Sanna‐Cherchi, Richard P. Lifton, Terry Watnick, York Pei, Vicente E. Torres, Stefan Somlo - Journal of Clinical Investigation 2017 cited by 208
- miR-17∼92 miRNA cluster promotes kidney cyst growth in polycystic kidney disease
Authors: Vishal Patel, Darren R. Williams, Sachin Hajarnis, Ryan W. Hunter, Marco Pontoglio, Stefan Somlo, Peter Igarashi - National Academy of Sciences, Proceedings of the National Academy of Sciences 2013 cited by 180
- Ciliary Mechanisms of Cyst Formation in Polycystic Kidney Disease
Authors: Ming Ma, Anna‐Rachel Gallagher, Stefan Somlo - Cold Spring Harbor Perspectives in Biology 2017 cited by 135
- Polycystin-2 Activation by Inositol 1,4,5-Trisphosphate-induced Ca2+ Release Requires Its Direct Association with the Inositol 1,4,5-Trisphosphate Receptor in a Signaling Microdomain
Authors: Eva Sammels, Benoit Devogelaere, Djalila Mekahli, Geert Bultynck, Ludwig Missiaen, Jan B. Parys, Yiqiang Cai, Stefan Somlo, Humbert De Smedt - Journal of Biological Chemistry 2010 cited by 126
- The C-terminal tail of polycystin-1 suppresses cystic disease in a mitochondrial enzyme-dependent fashion
Authors: Laura Onuchic, Valeria Padovano, Giorgia Schena, Vanathy Rajendran, Ke Dong, Xiaojian Shi, Raj Pandya, Victoria Rai, Nikolay Gresko, Omair Ahmed, TuKiet T. Lam, Weiwei Wang, Hongying Shen, Stefan Somlo, Michael J. Caplan - Nature Communications 2023 cited by 41
- Chemical modifier screen identifies HDAC inhibitors as suppressors of PKD models
Authors: Ying Cao, Nicole Semanchik, Seung Hun Lee, Stefan Somlo, Paolo Emilio Barbano, Ronald R. Coifman, Zhaoxia Sun - National Academy of Sciences, Proceedings of the National Academy of Sciences 2009 cited by 210
- Polycystin-1: a master regulator of intersecting cystic pathways
Authors: Sorin V. Fedeles, Anna‐Rachel Gallagher, Stefan Somlo - Trends in Molecular Medicine 2014 cited by 129
- The polycystins are modulated by cellular oxygen-sensing pathways and regulate mitochondrial function
Authors: Valeria Padovano, Ivana Y. Kuo, Lindsey K. Stavola, Hans R. Aerni, Benjamin Flaherty, Hannah C. Chapin, Ming Ma, Stefan Somlo, Alessandra Boletta, Barbara E. Ehrlich, Jesse Rinehart, Michael J. Caplan - Molecular Biology of the Cell 2016 cited by 101
