Stephen B. Liggett
Active 1989–2024
- 113
- Papers
- 22,125
- Citations
- 88
- h-index
- 112
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Medicine42.9%
- Biochemistry, Genetics and Molecular Biology37%
- Nursing6.2%
- Neuroscience5.4%
- Pharmacology, Toxicology and Pharmaceutics4.4%
- Immunology and Microbiology1.4%
- Other2.7%
Topics
- Receptor Mechanisms and Signaling9.7%
- Asthma and respiratory diseases4.2%
- Cardiac electrophysiology and arrhythmias3.5%
- Neuropeptides and Animal Physiology3.3%
- Ion channel regulation and function2.8%
- Biochemical Analysis and Sensing Techniques2.6%
- Other73.9%
Coauthors
- Gerald W. Dorn14
- Steven S. An11
- Donghwa Kim10
- Scott T. Weiss8
- John N. Lorenz7
- Jung A. Woo7
- Margaret G. Eason7
- Stuart A. Green7
- Dennis W. McGraw6
- Kersten M. Small6
- William A. Goddard6
- Brian D. Hoit5
- Cynthia Koziol‐White5
- Kelan G. Tantisira5
- Lynne E. Wagoner5
- Reynold A. Panettieri5
- Richard A. Walsh5
- Stephen P. Peters5
- Arnold Schwartz4
- David E. Kang4
- Deborah A. Rathz4
- Debra A. Schwinn4
- Elliot Israel4
- Harvey S. Hahn4
All papers
- Bitter taste receptors on airway smooth muscle bronchodilate by localized calcium signaling and reverse obstruction
Authors: Deepak A. Deshpande, Wayne C. H. Wang, Elizabeth L McIlmoyle, Kathryn S. Robinett, Rachel Schillinger, Steven S. An, James S.K. Sham, Stephen B. Liggett - Nature Medicine 2010 cited by 664
- Evaluation of the clinical impact of repeat application of hydrogel-forming microneedle array patches
Authors: Rehan Al-Kasasbeh, A. J. Brady, Aaron J. Courtenay, Eneko Larrañeta, Maelíosa McCrudden, Donal O’Kane, Stephen B. Liggett, Ryan F. Donnelly - Drug Delivery and Translational Research 2020 cited by 106
- Defining an olfactory receptor function in airway smooth muscle cells
Authors: William H. Aisenberg, Jessie Huang, Wanqu Zhu, Premraj Rajkumar, R Armas Cruz, Lakshmi Santhanam, Niranjana Natarajan, Hwan Mee Yong, Breann De Santiago, Jung Jin Oh, A‐Rum Yoon, Reynold A. Panettieri, Oliver Homann, John K. Sullivan, Stephen B. Liggett, Jennifer L. Pluznick, Steven S. An - Scientific Reports 2016 cited by 120
- Human phospholamban null results in lethal dilated cardiomyopathy revealing a critical difference between mouse and human
Authors: Kobra Haghighi, Fotis Kolokathis, Luke Pater, Roy A. Lynch, Michio Asahi, Anthony O. Gramolini, Guo‐Chang Fan, Dimitris Tsiapras, Harvey S. Hahn, Stamatis Adamopoulos, Stephen B. Liggett, Gerald W. Dorn, David H. MacLennan, Dimitrios Th. Kremastinos, Evangelia G. Kranias - Journal of Clinical Investigation 2003 cited by 458
- Extraoral bitter taste receptors as mediators of off‐target drug effects
Authors: Adam A. Clark, Stephen B. Liggett, Steven D. Munger - The FASEB Journal 2012 cited by 154
- Predicted structure and cell signaling of TAS2R14 reveal receptor hyper-flexibility for detecting diverse bitter tastes
Authors: А. Ю. Токмакова, Donghwa Kim, Brian Güthrie, Soo‐Kyung Kim, William A. Goddard, Stephen B. Liggett - iScience 2023 cited by 31
- PKC-α regulates cardiac contractility and propensity toward heart failure
Authors: Julian C. Braz, Kimberly N. Gregory, Anand Pathak, Wen Zhao, Bogachan Sahin, Raisa Klevitsky, Thomas F. Kimball, John N. Lorenz, Angus C. Nairn, Stephen B. Liggett, Ilona Bódi, Su Wang, Arnold Schwartz, Edward G. Lakatta, Anna Depaoli-Roach, Jeffrey Robbins, Timothy E. Hewett, James Bibb, Margaret V. Westfall, Evangelia G. Kranias, Jeffery D. Molkentin - Nature Medicine 2004 cited by 593
- Activated cofilin exacerbates tau pathology by impairing tau-mediated microtubule dynamics
Authors: Jung A. Woo, Tian Liu, Cenxiao Fang, Sara Cazzaro, Teresa R. Kee, Patrick LePochat, Ksenia Yrigoin, Courtney Penn, Xingyu Zhao, Xinming Wang, Stephen B. Liggett, David E. Kang - Communications Biology 2019 cited by 72
- Identification and Characterization of Novel Bronchodilator Agonists Acting at Human Airway Smooth Muscle Cell TAS2R5
Authors: Donghwa Kim, Steven S. An, Hong Lam, James W. Leahy, Stephen B. Liggett - ACS Pharmacology & Translational Science 2020 cited by 23
- A Par3/LIM Kinase/Cofilin Pathway Mediates Human Airway Smooth Muscle Relaxation by TAS2R14
Authors: Jung A. Woo, Maria A. Castaño, Teresa R. Kee, Jordan Lee, Cynthia Koziol‐White, Steven S. An, Donghwa Kim, David E. Kang, Stephen B. Liggett - American Journal of Respiratory Cell and Molecular Biology 2023 cited by 17
- A GRK5 polymorphism that inhibits β-adrenergic receptor signaling is protective in heart failure
Authors: Stephen B. Liggett, Sharon Cresci, Reagan Kelly, Faisal Syed, Scot J. Matkovich, Harvey S. Hahn, Abhinav Diwan, Jeffrey S. Martini, Li Sparks, Rohan R. Parekh, John A. Spertus, Walter J. Koch, Sharon L. R. Kardia, Gerald W. Dorn - Nature Medicine 2008 cited by 321
- Phosphorylation Barcoding as a Mechanism of Directing GPCR Signaling
Authors: Stephen B. Liggett - Science Signaling 2011 cited by 144
- Structures and Agonist Binding Sites of Bitter Taste Receptor TAS2R5 Complexed with Gi Protein and Validated against Experiment
Authors: Moon Young Yang, Soo‐Kyung Kim, Donghwa Kim, Stephen B. Liggett, William A. Goddard - The Journal of Physical Chemistry Letters 2021 cited by 21
- Analysis of the complete genome sequences of human rhinovirus
Authors: Ann C. Palmenberg, Jennifer A. Rathe, Stephen B. Liggett - Journal of Allergy and Clinical Immunology 2010 cited by 131
- Bitter Taste Receptor Function in Asthmatic and Nonasthmatic Human Airway Smooth Muscle Cells
Authors: Kathryn S. Robinett, Cynthia Koziol‐White, Arda Akoluk, Steven S. An, Reynold A. Panettieri, Stephen B. Liggett - American Journal of Respiratory Cell and Molecular Biology 2013 cited by 87
- β-Arrestin2 oligomers impair the clearance of pathological tau and increase tau aggregates
Authors: Jung A. Woo, Tian Liu, Cenxiao Fang, Maria A. Castaño, Teresa R. Kee, Ksenia Yrigoin, Yan Yan, Sara Cazzaro, Jenet Matlack, Xinming Wang, Xingyu Zhao, David E. Kang, Stephen B. Liggett - National Academy of Sciences, Proceedings of the National Academy of Sciences 2020 cited by 45
- A Gain-of-function Polymorphism in a G-protein Coupling Domain of the Human β1-Adrenergic Receptor
Authors: Deborah A. Mason, Jason D. Moore, Stuart A. Green, Stephen B. Liggett - Journal of Biological Chemistry 1999 cited by 586
- Influence of β2-Adrenergic Receptor Genotypes on Signal Transduction in Human Airway Smooth Muscle Cells
Authors: S A Green, J Turki, P.A. Bejarano, Ian P. Hall, Stephen B. Liggett - American Journal of Respiratory Cell and Molecular Biology 1995 cited by 441
- Early and Delayed Consequences of β 2 -Adrenergic Receptor Overexpression in Mouse Hearts
Authors: Stephen B. Liggett, Nicole M. Tepe, John N. Lorenz, Amy M. Canning, Tamara D. Jantz, Sayaka Mitarai, Atsuko Yatani, Gerald W. Dorn - Circulation 2000 cited by 396
- Simultaneous coupling of alpha 2-adrenergic receptors to two G-proteins with opposing effects. Subtype-selective coupling of alpha 2C10, alpha 2C4, and alpha 2C2 adrenergic receptors to Gi and Gs.
Authors: Margaret G. Eason, Hitoshi Kurose, Brian D. Holt, John R. Raymond, Stephen B. Liggett - Journal of Biological Chemistry 1992 cited by 328
- Pharmacology and Physiology of Human Adrenergic Receptor polymorphisms
Authors: Kersten M. Small, Dennis W. McGraw, Stephen B. Liggett - The Annual Review of Pharmacology and Toxicology 2003 cited by 326
- Molecular modeling, organ culture and reverse genetics for a newly identified human rhinovirus C
Authors: Yury A. Bochkov, Ann C. Palmenberg, Wai-Ming Lee, Jennifer A. Rathe, Svetlana P. Amineva, Xin Sun, Thomas R. Pasic, Nizar N. Jarjour, Stephen B. Liggett, James E. Gern - Nature Medicine 2011 cited by 200
- The odorant receptor OR2W3 on airway smooth muscle evokes bronchodilation via a cooperative chemosensory tradeoff between TMEM16A and CFTR
Authors: Jessie Huang, Hong Lam, Cynthia Koziol‐White, Nathachit Limjunyawong, Donghwa Kim, Nicholas Kim, N. Karmacharya, Premraj Rajkumar, Danielle Firer, Nicholas M. Dalesio, Joseph A. Jude, Richard C. Kurten, Jennifer L. Pluznick, Deepak A. Deshpande, Raymond B. Penn, Stephen B. Liggett, Reynold A. Panettieri, Xinzhong Dong, Steven S. An - National Academy of Sciences, Proceedings of the National Academy of Sciences 2020 cited by 26
- Amino-Terminal Polymorphisms of the Human .beta.2-Adrenergic Receptor Impart Distinct Agonist-Promoted Regulatory Properties
Authors: Stuart A. Green, Jamal Turki, Michael A. Innis, Stephen B. Liggett - Biochemistry 1994 cited by 775
