Stephen C. West
Active 1977–2025
- 145
- Papers
- 29,455
- Citations
- 107
- h-index
- 144
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Biochemistry, Genetics and Molecular Biology76.2%
- Medicine17.1%
- Agricultural and Biological Sciences1.8%
- Environmental Science1.6%
- Immunology and Microbiology1.2%
- Neuroscience0.9%
- Other1.2%
Topics
- DNA Repair Mechanisms23.5%
- CRISPR and Genetic Engineering7.8%
- PARP inhibition in cancer therapy5.7%
- Genomics and Chromatin Dynamics4.2%
- DNA and Nucleic Acid Chemistry3.7%
- Carcinogens and Genotoxicity Assessment3.7%
- Other51.4%
Coauthors
- Simon J. Boulton12
- Andrzej Stasiak11
- Jean‐Yves Masson11
- Fiona E. Benson10
- Michael J. McIlwraith10
- Alicja Z. Stasiak9
- Yilun Liu9
- Joao Matos8
- Carol A. Parsons7
- Edward H. Egelman7
- Ivan Ahel7
- Miguel G. Blanco7
- Paul Howard-Flanders7
- Adelina A. Davies6
- Era Cassuto6
- Eric Van Dyck6
- Irina R. Tsaneva6
- Madalena Tarsounas6
- Mark Skehel6
- Peter Baumann6
- Ulrich Rass6
- Alberto Ciccia5
- Andrew J. Deans5
- Angelos Constantinou5
All papers
- POLQ seals post-replicative ssDNA gaps to maintain genome stability in BRCA-deficient cancer cells
Authors: Ondrej Beláň, Marie Sebald, Marek Adamowicz, Roopesh Anand, Aleksandra Vančevska, Joana Neves, Vera Grinkevich, Graeme Hewitt, Sandra Segura‐Bayona, Roberto Bellelli, Helen M.R. Robinson, Geoff S. Higgins, Graeme C.M. Smith, Stephen C. West, David Rueda, Simon J. Boulton - Molecular Cell 2022 cited by 129
- Repeat expansions confer WRN dependence in microsatellite-unstable cancers
Authors: Niek van Wietmarschen, Sriram Sridharan, William J. Nathan, Anthony Tubbs, Edmond M. Chan, Elsa Callén, Wei Wu, Frida Belinky, Veenu Tripathi, Nancy Wong, Kyla Foster, Javad Noorbakhsh, Kiran Garimella, Abimael Cruz-Migoni, Joshua A. Sommers, Yongqing Huang, Ashir A. Borah, Jonathan T. Smith, Jérémie Kalfon, Nikolas Kesten, Kasper Fugger, Robert L. Walker, Egor Dolzhenko, Michael A. Eberle, Bruce E. Hayward, Karen Usdin, Catherine H. Freudenreich, Robert M. Brosh, Stephen C. West, Peter J. McHugh, Paul S. Meltzer, Adam J. Bass, André Nussenzweig - Nature 2020 cited by 199
- Defective ALC1 nucleosome remodeling confers PARPi sensitization and synthetic lethality with HRD
Authors: Graeme Hewitt, Valérie Borel, Sandra Segura‐Bayona, Tohru Takaki, Phil Ruis, Roberto Bellelli, Laura C. Lehmann, Lucia Sommerová, Aleksandra Vančevska, Antonia Tomás‐Loba, Kang Zhu, C.D.O. Cooper, Kasper Fugger, Harshil Patel, Robert Goldstone, Deborah Schneider-Luftman, Ellie Herbert, Gordon Stamp, Rachel Brough, Stephen J. Pettitt, Christopher J. Lord, Stephen C. West, Ivan Ahel, Dragana Ahel, J. Ross Chapman, Sebastian Deindl, Simon J. Boulton - Molecular Cell 2020 cited by 164
- DNA interstrand crosslink repair and cancer
Authors: Andrew J. Deans, Stephen C. West - Nature reviews. Cancer 2011 cited by 1,033
- Poly(ADP-ribose)–Dependent Regulation of DNA Repair by the Chromatin Remodeling Enzyme ALC1
Authors: Dragana Ahel, Zuzana Hořejšı́, Nicola Wiechens, Sophie E. Polo, Elisa Garcia-Wilson, Ivan Ahel, Helen R. Flynn, Mark Skehel, Stephen C. West, Stephen P. Jackson, Tom Owen‐Hughes, Simon J. Boulton - Science 2009 cited by 600
- Targeting the nucleotide salvage factor DNPH1 sensitizes BRCA -deficient cells to PARP inhibitors
Authors: Kasper Fugger, Ilirjana Bajrami, Mariana Silva dos Santos, Sarah Jane Young, Simone Kunzelmann, Geoff Kelly, Graeme Hewitt, Harshil Patel, Robert Goldstone, Thomas Carell, Simon J. Boulton, James I. MacRae, Ian A. Taylor, Stephen C. West - Science 2021 cited by 134
- Poly(ADP-ribose)-binding zinc finger motifs in DNA repair/checkpoint proteins
Authors: Ivan Ahel, Dragana Ahel, Takahiro Matsusaka, Allison J. Clark, Jonathon Pines, Simon J. Boulton, Stephen C. West - Nature 2008 cited by 425
- Role of BRCA2 in Control of the RAD51 Recombination and DNA Repair Protein
Authors: Adelina A. Davies, Jean‐Yves Masson, Michael J. McIlwraith, Alicja Z. Stasiak, Andrzej Stasiak, Ashok R. Venkitaraman, Stephen C. West - Molecular Cell 2001 cited by 714
- Structure and function of the RAD51B–RAD51C–RAD51D–XRCC2 tumour suppressor
Authors: Luke A. Greenhough, Chih‐Chao Liang, Ondrej Beláň, Simone Kunzelmann, Sarah Maslen, Monica C. Rodrigo-Brenni, Roopesh Anand, Mark Skehel, Simon J. Boulton, Stephen C. West - Nature 2023 cited by 81
- CDK-dependent phosphorylation of BRCA2 as a regulatory mechanism for recombinational repair
Authors: Fumiko Esashi, Nicole Christ, Julian Gannon, Yilun Liu, Tim Hunt, Maria Jasin, Stephen C. West - Nature 2005 cited by 476
- Coordinated Actions of SLX1-SLX4 and MUS81-EME1 for Holliday Junction Resolution in Human Cells
Authors: Haley D.M. Wyatt, Shriparna Sarbajna, Joao Matos, Stephen C. West - Molecular Cell 2013 cited by 305
- Tackling PARP inhibitor resistance
Authors: Kasper Fugger, Graeme Hewitt, Stephen C. West, Simon J. Boulton - Trends in cancer 2021 cited by 60
- Mechanism of single-stranded DNA annealing by RAD52–RPA complex
Authors: Chih-Chao Liang, Luke A. Greenhough, Laura Masino, Sarah Maslen, Ilirjana Bajrami, Marcel Tuppi, Mark Skehel, Ian A. Taylor, Stephen C. West - Nature 2024 cited by 50
- Defective DNA Repair and Neurodegenerative Disease
Authors: Ulrich Rass, Ivan Ahel, Stephen C. West - Cell 2007 cited by 366
- Holliday Junction Resolvases
Authors: Haley D.M. Wyatt, Stephen C. West - Cold Spring Harbor Perspectives in Biology 2014 cited by 206
- Unresolved recombination intermediates lead to ultra-fine anaphase bridges, chromosome breaks and aberrations
Authors: Ying Wai Chan, Kasper Fugger, Stephen C. West - Nature Cell Biology 2017 cited by 198
- The breast cancer tumor suppressor BRCA2 promotes the specific targeting of RAD51 to single-stranded DNA
Authors: Tina Thorslund, Michael J. McIlwraith, Sarah A. Compton, Sergey Lekomtsev, Mark Petronczki, Jack D. Griffith, Stephen C. West - Nature Structural & Molecular Biology 2010 cited by 256
- Identification of Holliday junction resolvases from humans and yeast
Authors: Stephen C.Y. Ip, Ulrich Rass, Miguel G. Blanco, Helen R. Flynn, Mark Skehel, Stephen C. West - Nature 2008 cited by 415
- The neurodegenerative disease protein aprataxin resolves abortive DNA ligation intermediates
Authors: Ivan Ahel, Ulrich Rass, Sherif F. El‐Khamisy, Sachin Katyal, Paula Clements, Peter J. McKinnon, Keith W. Caldecott, Stephen C. West - Nature 2006 cited by 389
- Stabilization of RAD51 nucleoprotein filaments by the C-terminal region of BRCA2
Authors: Fumiko Esashi, Vitold E. Galkin, Xiong Yu, Edward H. Egelman, Stephen C. West - Nature Structural & Molecular Biology 2007 cited by 280
- Senataxin, Defective in the Neurodegenerative Disorder Ataxia with Oculomotor Apraxia 2, Lies at the Interface of Transcription and the DNA Damage Response
Authors: Özlem Yüce, Stephen C. West - Molecular and Cellular Biology 2012 cited by 198
- Molecular views of recombination proteins and their control
Authors: Stephen C. West - Nature Reviews Molecular Cell Biology 2003 cited by 940
- Human Rad51 Protein Promotes ATP-Dependent Homologous Pairing and Strand Transfer Reactions In Vitro
Authors: Peter Baumann, Fiona E. Benson, Stephen C. West - Cell 1996 cited by 688
- Role of the human RAD51 protein in homologous recombination and double-stranded-break repair
Authors: Peter Baumann, Stephen C. West - Trends in Biochemical Sciences 1998 cited by 570
