Stephen Gottschalk
Active 1988–2026
- 141
- Papers
- 18,722
- Citations
- 78
- h-index
- 134
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Medicine74.4%
- Biochemistry, Genetics and Molecular Biology13.7%
- Immunology and Microbiology9.6%
- Engineering0.9%
- Materials Science0.5%
- Neuroscience0.4%
- Other0.5%
Topics
- CAR-T cell therapy research19.9%
- Immune Cell Function and Interaction7.6%
- Virus-based gene therapy research7.4%
- Immunotherapy and Immune Responses6%
- Nanowire Synthesis and Applications4.1%
- Cancer Immunotherapy and Biomarkers4%
- Other51%
Coauthors
- Cliona M. Rooney33
- Helen E. Heslop33
- Malcolm K. Brenner33
- Meng-Fen Wu22
- Adrian P. Gee17
- Giedre Krenciute17
- Gianpietro Dotti16
- Hao Liu16
- Mireya Paulina Velasquez16
- Swati Naik16
- Aimee C. Talleur15
- Deanna Langfitt15
- Nabil Ahmed14
- Brandon M. Triplett13
- Christopher DeRenzo13
- Zhongzhen Yi13
- Ann M. Leen12
- Bambi Grilley11
- Bilal Omer11
- Catherine M. Bollard11
- Claudia Gerken11
- Phuong Nguyen10
- Meenakshi Hegde9
- Rebecca Epperly9
All papers
- HER2-Specific Chimeric Antigen Receptor–Modified Virus-Specific T Cells for Progressive Glioblastoma
Authors: Nabil Ahmed, Vita S. Brawley, Meenakshi Hegde, Kevin Bielamowicz, Mamta Kalra, Daniel Landi, Catherine Robertson, Tara Gray, Oumar Diouf, Amanda Wakefield, Alexia Ghazi, Claudia Gerken, Zhongzhen Yi, Aidin Ashoori, Meng-Fen Wu, Hao Liu, Cliona M. Rooney, Gianpietro Dotti, Adrian P. Gee, Jack Su, Yvonne Kew, David S. Baskin, Yi Jonathan Zhang, Pamela New, Bambi Grilley, Milica Stojakovic, John Hicks, Suzanne Z. Powell, Malcolm K. Brenner, Helen E. Heslop, Robert G. Grossman, Winfried S. Wels, Stephen Gottschalk - JAMA Oncology 2017 cited by 837
- Deleting DNMT3A in CAR T cells prevents exhaustion and enhances antitumor activity
Authors: Brooke Prinzing, Caitlin C. Zebley, Christopher T. Petersen, Yiping Fan, Alejandro Allo Anido, Zhongzhen Yi, Phuong Nguyen, Haley Houke, Matthew Bell, Dalia Haydar, Charmaine Brown, Shannon K. Boi, Shanta Alli, Jeremy Chase Crawford, Janice M. Riberdy, Jeoung-Eun Park, Sheng Zhou, Mireya Paulina Velasquez, Chris DeRenzo, Cícera R. Lazzarotto, Shengdar Q. Tsai, Peter Vogel, Shondra M. Pruett‐Miller, Deanna Langfitt, Stephen Gottschalk, Ben Youngblood, Giedre Krenciute - Science Translational Medicine 2021 cited by 332
- Human Epidermal Growth Factor Receptor 2 (HER2) –Specific Chimeric Antigen Receptor–Modified T Cells for the Immunotherapy of HER2-Positive Sarcoma
Authors: Nabil Ahmed, Vita S. Brawley, Meenakshi Hegde, Catherine Robertson, Alexia Ghazi, Claudia Gerken, Enli Liu, Olga Dakhova, Aidin Ashoori, Amanda Corder, Tara Gray, Meng-Fen Wu, Hao Liu, John Hicks, Nino Rainusso, Gianpietro Dotti, Zhuyong Mei, Bambi Grilley, Adrian P. Gee, Cliona M. Rooney, Malcolm K. Brenner, Helen E. Heslop, Winfried S. Wels, Lisa L. Wang, Peter M. Anderson, Stephen Gottschalk - Journal of Clinical Oncology 2015 cited by 979
- Tandem CAR T cells targeting HER2 and IL13Rα2 mitigate tumor antigen escape
Authors: Meenakshi Hegde, Malini Mukherjee, Zakaria Grada, Antonella Pignata, Daniel Landi, Shoba A. Navai, Amanda Wakefield, Kristen Fousek, Kevin Bielamowicz, Kevin Chow, Vita S. Brawley, Tiara T. Byrd, Simone Krebs, Stephen Gottschalk, Winfried S. Wels, Matthew L. Baker, Gianpietro Dotti, Maksim Mamonkin, Malcolm K. Brenner, Jordan S. Orange, Nabil Ahmed - Journal of Clinical Investigation 2016 cited by 672
- RASA2 ablation in T cells boosts antigen sensitivity and long-term function
Authors: Julia Carnevale, Eric Shifrut, Nupura Kale, William A. Nyberg, Franziska Blaeschke, Yan Yi Chen, Zhongmei Li, Sagar P. Bapat, Morgan E. Diolaiti, Patrick C. O’Leary, Shane Vedova, Julia A. Belk, Bence Dániel, Theodore L. Roth, Stefanie Bachl, Alejandro Allo Anido, Brooke Prinzing, Jorge Ibañez-Vega, Shannon Lange, Dalia Haydar, Marie Luetke-Eversloh, Maëlys Born-Bony, Bindu Hegde, Scott C. Kogan, Tobias Feuchtinger, Hideho Okada, Ansuman T. Satpathy, Kevin Shannon, Stephen Gottschalk, Justin Eyquem, Giedre Krenciute, Alan Ashworth, Alexander Marson - Nature 2022 cited by 223
- CAR T Cell Therapy for Solid Tumors: Bright Future or Dark Reality?
Authors: Jessica Wagner, Elizabeth Wickman, Christopher DeRenzo, Stephen Gottschalk - Molecular Therapy 2020 cited by 374
- CD70-specific CAR T cells have potent activity against acute myeloid leukemia without HSC toxicity
Authors: Tim Sauer, Kathan Parikh, Sandhya Sharma, Bilal Omer, David Sedloev, Qian Chen, Linus Angenendt, Christoph Schliemann, Michael Schmitt, Carsten Müller‐Tidow, Stephen Gottschalk, Cliona M. Rooney - Blood 2021 cited by 217
- Interleukin-15-armoured GPC3 CAR T cells for patients with solid cancers
Authors: Pavel Sumazin, Andras Heczey, John M. Maris, Antonino Montalbano, Amy N. Courtney, Jennifer Pogoriler, Sachin G. Thakkar, Gianpietro Dotti, David Steffin, Premal Lulla, Natalia Lapteva, Dolores López‐Terrada, Zhuyong Mei, Carlos A. Ramos, Malcolm K. Brenner, Ramy Sweidan, Stephen Gottschalk, Huimin Zhang, Nisha Ghatwai, Navin Varadarajan, Leonid S. Metelitsa, Kalyani Patel, Helen E. Heslop, Azlann Arnett, Prakash Masand, Tao Wang, Tannaz Armaghany, Julien Fleurence, Purva Rathi, Bambi Grilley, Daniel Martínez, Deborah Lyon - Nature 2024 cited by 207
- Engineered Cytokine Signaling to Improve CAR T Cell Effector Function
Authors: Matthew Bell, Stephen Gottschalk - Frontiers in Immunology 2021 cited by 151
- Transgenic Expression of IL15 Improves Antiglioma Activity of IL13Rα2-CAR T Cells but Results in Antigen Loss Variants
Authors: Giedre Krenciute, Brooke Prinzing, Zhongzhen Yi, Meng-Fen Wu, Hao Liu, Gianpietro Dotti, Irina V. Balyasnikova, Stephen Gottschalk - Cancer Immunology Research 2017 cited by 312
- Antitumor Effects of Chimeric Receptor Engineered Human T Cells Directed to Tumor Stroma
Authors: Sunitha Kakarla, Kevin Chow, Melinda Mata, Donald R. Shaffer, Xiao‐Tong Song, Meng-Fen Wu, Hao Liu, Lisa L. Wang, David R. Rowley, Klaus Pfizenmaier, Stephen Gottschalk - Molecular Therapy 2013 cited by 338
- Constitutive Signaling from an Engineered IL7 Receptor Promotes Durable Tumor Elimination by Tumor-Redirected T Cells
Authors: Thomas Shum, Bilal Omer, Haruko Tashiro, Robert L. Kruse, Dimitrios L. Wagner, Kathan Parikh, Zhongzhen Yi, Tim Sauer, Daofeng Liu, Robin Parihar, Paul Castillo, Hao Liu, Malcolm K. Brenner, Leonid S. Metelitsa, Stephen Gottschalk, Cliona M. Rooney - Cancer Discovery 2017 cited by 292
- Off-the-Shelf Virus-Specific T Cells to Treat BK Virus, Human Herpesvirus 6, Cytomegalovirus, Epstein-Barr Virus, and Adenovirus Infections After Allogeneic Hematopoietic Stem-Cell Transplantation
Authors: Ifigeneia Tzannou, Αναστασία Παπαδοπούλου, Swati Naik, Kathryn Leung, Caridad Martinez, Carlos A. Ramos, George Carrum, Ghadir Sasa, Premal Lulla, Ayumi Watanabe, Manik Kuvalekar, Adrian P. Gee, Meng-Fen Wu, Hao Liu, Bambi Grilley, Robert A. Krance, Stephen Gottschalk, Malcolm K. Brenner, Cliona M. Rooney, Helen E. Heslop, Ann M. Leen, Bilal Omer - Journal of Clinical Oncology 2017 cited by 450
- Allogeneic CAR Cell Therapy—More Than a Pipe Dream
Authors: Kenneth J. Caldwell, Stephen Gottschalk, Aimee C. Talleur - Frontiers in Immunology 2021 cited by 128
- NK Cells Expressing a Chimeric Activating Receptor Eliminate MDSCs and Rescue Impaired CAR-T Cell Activity against Solid Tumors
Authors: Robin Parihar, Charlotte Helena Rivas, Mai Huynh, Bilal Omer, Natalia Lapteva, Leonid S. Metelitsa, Stephen Gottschalk, Cliona M. Rooney - Cancer Immunology Research 2019 cited by 249
- Cell-surface antigen profiling of pediatric brain tumors: B7-H3 is consistently expressed and can be targeted via local or systemic CAR T-cell delivery
Authors: Dalia Haydar, Haley Houke, Jason Chiang, Zhongzhen Yi, Zelda Odé, Kenneth J. Caldwell, Xiaoyan Zhu, Kimberly Mercer, Jennifer L. Stripay, Timothy I. Shaw, Peter Vogel, Christopher DeRenzo, Suzanne J. Baker, Martine F. Roussel, Stephen Gottschalk, Giedre Krenciute - Neuro-Oncology 2020 cited by 144
- Design and development of therapies using chimeric antigen receptor‐expressing T cells
Authors: Gianpietro Dotti, Stephen Gottschalk, Barbara Savoldo, Malcolm K. Brenner - Immunological Reviews 2013 cited by 507
- Tumor response and endogenous immune reactivity after administration of HER2 CAR T cells in a child with metastatic rhabdomyosarcoma
Authors: Meenakshi Hegde, Sujith K. Joseph, Farzana Pashankar, Christopher DeRenzo, Khaled Sanber, Shoba A. Navai, Tiara T. Byrd, John Hicks, Mina L. Xu, Claudia Gerken, Mamta Kalra, Catherine Robertson, Huimin Zhang, Ankita Shree, Birju Mehta, Olga Dakhova, Vita S. Salsman, Bambi Grilley, Adrian P. Gee, Gianpietro Dotti, Helen E. Heslop, Malcolm K. Brenner, Winfried S. Wels, Stephen Gottschalk, Nabil Ahmed - Nature Communications 2020 cited by 167
- CD19-CAR T cells undergo exhaustion DNA methylation programming in patients with acute lymphoblastic leukemia
Authors: Caitlin C. Zebley, Charmaine Brown, Mi Tian, Yiping Fan, Shanta Alli, Shannon K. Boi, Giovanni Galletti, Enrico Lugli, Deanna Langfitt, Jean‐Yves Métais, Timothy Lockey, Michael M. Meagher, Brandon M. Triplett, Aimee C. Talleur, Stephen Gottschalk, Ben Youngblood - Cell Reports 2021 cited by 103
- IL15 modification enables CAR T cells to act as a dual targeting agent against tumor cells and myeloid-derived suppressor cells in GBM
Authors: Μαρκέλλα Ζαννίκου, Joseph Duffy, Rebecca Levine, Maggie Seblani, Qianli Liu, Aaron Presser, Víctor A. Arrieta, Christopher J. Chen, Adam M. Sonabend, Craig Horbinski, Catalina Lee-Chang, Jason Miska, Maciej S. Lesniak, Stephen Gottschalk, Irina V. Balyasnikova - Journal for ImmunoTherapy of Cancer 2023 cited by 82
- Autologous HER2-specific CAR T cells after lymphodepletion for advanced sarcoma: a phase 1 trial
Authors: Meenakshi Hegde, Shoba A. Navai, Christopher DeRenzo, Sujith K. Joseph, Khaled Sanber, Meng‐Fen Wu, Ahmed Z. Gad, Katherine A. Janeway, Matthew Campbell, Dolores Mullikin, Zeid Nawas, Catherine Robertson, Pretty Mathew, Huimin Zhang, Birju Mehta, Raksha R. Bhat, Angela M. Major, Ankita Shree, Claudia Gerken, Mamta Kalra, Rikhia Chakraborty, Sachin G. Thakkar, Olga Dakhova, Vita S. Salsman, Bambi Grilley, Natalia Lapteva, Adrian P. Gee, Gianpietro Dotti, Riyue Bao, Ahmed Hamed Salem, Tao Wang, Malcolm K. Brenner, Helen E. Heslop, Winfried S. Wels, John Hicks, Stephen Gottschalk, Nabil Ahmed - Nature Cancer 2024 cited by 80
- Synapse-tuned CARs enhance immune cell anti-tumor activity
Authors: Peter Chockley, Jorge Ibañez-Vega, Giedre Krenciute, Lindsay J. Talbot, Stephen Gottschalk - Nature Biotechnology 2023 cited by 57
- T cell dysfunction and therapeutic intervention in cancer
Authors: Caitlin C. Zebley, Dietmar Zehn, Stephen Gottschalk, Hongbo Chi - Nature Immunology 2024 cited by 115
- HER2-Specific T Cells Target Primary Glioblastoma Stem Cells and Induce Regression of Autologous Experimental Tumors
Authors: Nabil Ahmed, Vita S. Salsman, Yvonne Kew, Donald R. Shaffer, Suzanne Z. Powell, Yi J Zhang, Robert G. Grossman, Helen E. Heslop, Stephen Gottschalk - Clinical Cancer Research 2010 cited by 386
