Thomas A. Steitz
Active 1966–2021
- 159
- Papers
- 47,643
- Citations
- 121
- h-index
- 157
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Biochemistry, Genetics and Molecular Biology73.2%
- Medicine10.9%
- Immunology and Microbiology3.5%
- Materials Science2.6%
- Environmental Science2.3%
- Agricultural and Biological Sciences1.8%
- Other5.7%
Topics
- RNA and protein synthesis mechanisms15.7%
- RNA modifications and cancer8.7%
- Bacterial Genetics and Biotechnology5.6%
- RNA Research and Splicing5%
- DNA and Nucleic Acid Chemistry4.5%
- DNA Repair Mechanisms3.2%
- Other57.3%
Coauthors
- Peter B. Moore23
- Jimin Wang13
- Dieter Söll8
- Gregor Blaha7
- Nenad Ban7
- Yury S. Polikanov7
- Irene T. Weber6
- Poul Nissen6
- Satwik Kamtekar6
- David Bulkley5
- J Wang5
- J.L. Hansen5
- John J. Perona5
- Matthieu G. Gagnon5
- Scott Bailey5
- Yong Xiong5
- Andrea J. Berman4
- C.A. Innis4
- David L. Ollis4
- David McKay4
- Ivan B. Lomakin4
- Joan A. Steitz4
- Joseph A. Ippolito4
- José M. Lázaro4
All papers
- Ribosome-Targeting Antibiotics: Modes of Action, Mechanisms of Resistance, and Implications for Drug Design
Authors: Jinzhong Lin, Dejian Zhou, Thomas A. Steitz, Yury S. Polikanov, Matthieu G. Gagnon - Annual Review of Biochemistry 2018 cited by 393
- The Structural Basis of Ribosome Activity in Peptide Bond Synthesis
Authors: Poul Nissen, Jeffrey C. Hansen, Nenad Ban, Peter B. Moore, Thomas A. Steitz - Science 2000 cited by 2,275
- The Complete Atomic Structure of the Large Ribosomal Subunit at 2.4 Å Resolution
Authors: Nenad Ban, Poul Nissen, Jeffrey C. Hansen, Peter B. Moore, Thomas A. Steitz - Science 2000 cited by 3,309
- Structural insights into the role of rRNA modifications in protein synthesis and ribosome assembly
Authors: Yury S. Polikanov, Sergey Melnikov, Dieter Söll, Thomas A. Steitz - Nature Structural & Molecular Biology 2015 cited by 278
- Structural insights into the stabilization of MALAT1 noncoding RNA by a bipartite triple helix
Authors: Jessica A. Brown, David Bulkley, Jimin Wang, Max L. Valenstein, Therese A. Yario, Thomas A. Steitz, Joan A. Steitz - Nature Structural & Molecular Biology 2014 cited by 290
- A general two-metal-ion mechanism for catalytic RNA.
Authors: Thomas A. Steitz, Joan A. Steitz - National Academy of Sciences, Proceedings of the National Academy of Sciences 1993 cited by 1,154
- A proton wire to couple aminoacyl-tRNA accommodation and peptide-bond formation on the ribosome
Authors: Yury S. Polikanov, Thomas A. Steitz, C.A. Innis - Nature Structural & Molecular Biology 2014 cited by 247
- A new system for naming ribosomal proteins
Authors: Nenad Ban, Roland Beckmann, J.H.D. Cate, Jonathan D. Dinman, François Dragon, Steven R. Ellis, Denis L. J. Lafontaine, Lasse Lindahl, Anders Liljas, Jeffrey M. Lipton, Michael A. McAlear, Peter B. Moore, Harry F. Noller, Joaquín Ortega, Vikram Govind Panse, V. Ramakrishnan, C.M.T. Spahn, Thomas A. Steitz, Marek Tchórzewski, David Tollervey, Alan J. Warren, James R. Williamson, Daniel N. Wilson, Ada Yonath, Marat Yusupov - Current Opinion in Structural Biology 2014 cited by 575
- Structures of proline-rich peptides bound to the ribosome reveal a common mechanism of protein synthesis inhibition
Authors: Matthieu G. Gagnon, Raktim N. Roy, Ivan B. Lomakin, Tanja Florin, Alexander S. Mankin, Thomas A. Steitz - Nucleic Acids Research 2016 cited by 184
- A structural understanding of the dynamic ribosome machine
Authors: Thomas A. Steitz - Nature Reviews Molecular Cell Biology 2008 cited by 442
- The mechanism of inhibition of protein synthesis by the proline-rich peptide oncocin
Authors: Raktim N. Roy, Ivan B. Lomakin, Matthieu G. Gagnon, Thomas A. Steitz - Nature Structural & Molecular Biology 2015 cited by 186
- Revisiting the structures of several antibiotics bound to the bacterial ribosome
Authors: David Bulkley, C.A. Innis, Gregor Blaha, Thomas A. Steitz - National Academy of Sciences, Proceedings of the National Academy of Sciences 2010 cited by 309
- Structures of MLSBK Antibiotics Bound to Mutated Large Ribosomal Subunits Provide a Structural Explanation for Resistance
Authors: Daqi Tu, Gregor Blaha, Peter B. Moore, Thomas A. Steitz - Cell 2005 cited by 439
- How Hibernation Factors RMF, HPF, and YfiA Turn Off Protein Synthesis
Authors: Yury S. Polikanov, Gregor Blaha, Thomas A. Steitz - Science 2012 cited by 235
- DNA Polymerases: Structural Diversity and Common Mechanisms
Authors: Thomas A. Steitz - Journal of Biological Chemistry 1999 cited by 853
- U2504 Determines the Species Specificity of the A-Site Cleft Antibiotics:
Authors: G. Gurel, Gregor Blaha, Peter B. Moore, Thomas A. Steitz - Journal of Molecular Biology 2009 cited by 188
- Structural basis of bacterial transcription activation
Authors: Bin Liu, Chuan Hong, Rick Huang, Zhiheng Yu, Thomas A. Steitz - Science 2017 cited by 99
- Crystal Structure of the Oxazolidinone Antibiotic Linezolid Bound to the 50S Ribosomal Subunit
Authors: Joseph A. Ippolito, Z.F. Kanyo, Deping Wang, F. Franceschi, Peter B. Moore, Thomas A. Steitz, Erin M. Duffy - Journal of Medicinal Chemistry 2008 cited by 301
- A mechanism for all polymerases
Authors: Thomas A. Steitz - Nature 1998 cited by 596
- The Structures of Four Macrolide Antibiotics Bound to the Large Ribosomal Subunit
Authors: J.L. Hansen, Joseph A. Ippolito, Nenad Ban, Poul Nissen, Peter B. Moore, Thomas A. Steitz - Molecular Cell 2002 cited by 569
- An induced-fit mechanism to promote peptide bond formation and exclude hydrolysis of peptidyl-tRNA
Authors: T. Martin Schmeing, Kevin S. Huang, Scott A. Strobel, Thomas A. Steitz - Nature 2005 cited by 354
- Formation of the First Peptide Bond: The Structure of EF-P Bound to the 70 S Ribosome
Authors: Gregor Blaha, Robin E. Stanley, Thomas A. Steitz - Science 2009 cited by 228
- Structure of pyrrolysyl-tRNA synthetase, an archaeal enzyme for genetic code innovation
Authors: Jennifer M. Kavran, Sarath Gundllapalli, Patrick O’Donoghue, Markus Englert, Dieter Söll, Thomas A. Steitz - National Academy of Sciences, Proceedings of the National Academy of Sciences 2007 cited by 222
- Polyspecific pyrrolysyl-tRNA synthetases from directed evolution
Authors: Li-Tao Guo, Yane‐Shih Wang, Akiyoshi Nakamura, Daniel Eiler, Jennifer M. Kavran, Margaret L. Wong, Laura L. Kiessling, Thomas A. Steitz, Patrick O’Donoghue, Dieter Söll - National Academy of Sciences, Proceedings of the National Academy of Sciences 2014 cited by 122
