Thomas S. Kupper
Active 1986–2025
- 107
- Papers
- 24,145
- Citations
- 86
- h-index
- 105
- i10-index
Citations
Citation sources
Countries
Institutions
- Harvard University1.8%
- Brigham and Women's Hospital1.1%
- Inserm0.8%
- Dana-Farber Cancer Institute0.7%
- National Institutes of Health0.6%
- University of Pennsylvania0.5%
- Other94.5%
Fields
- Medicine46.2%
- Immunology and Microbiology32%
- Biochemistry, Genetics and Molecular Biology16.3%
- Pharmacology, Toxicology and Pharmaceutics1.4%
- Neuroscience1.1%
- Engineering0.6%
- Other2.4%
Topics
- Immune Cell Function and Interaction6.6%
- T-cell and B-cell Immunology6.3%
- Immunotherapy and Immune Responses6.1%
- Dermatology and Skin Diseases4%
- Psoriasis: Treatment and Pathogenesis2.9%
- Cell Adhesion Molecules Research2.8%
- Other71.3%
Coauthors
- Rachael A. Clark32
- Robert C. Fuhlbrigge16
- Jessica E. Teague11
- Gëorge F. Murphy10
- Youdong Pan10
- Rei Watanabe9
- Christoph Schlapbach8
- John T. O’Malley8
- Tian Tian8
- Ahmed Gehad7
- Chang Ook Park7
- Hitoshi Mizutani6
- Xiaodong Jiang6
- Christopher P. Elco5
- David C. Fisher5
- Harlan Robins5
- Ifor R. Williams5
- James G. Krueger5
- Luzheng Liu5
- Patrick M. Flood5
- Qian Zhan5
- Tobias Schatton5
- Caroline Robert4
- Elizabeth L. Lowry4
All papers
- Streptococcal pyrogenic exotoxin B cleaves GSDMA and triggers pyroptosis
Authors: Wanyan Deng, Yang Bai, Fan Deng, Youdong Pan, Shenglin Mei, Zengzhang Zheng, Rui Min, Zeyu Wu, Wu Li, Rui Miao, Zhibin Zhang, Thomas S. Kupper, Judy Lieberman, Xing Liu - Nature 2022 cited by 361
- Survival of tissue-resident memory T cells requires exogenous lipid uptake and metabolism
Authors: Youdong Pan, Tian Tian, Chang Ook Park, Serena Lofftus, Shenglin Mei, Xing Liu, Chi Luo, John T. O’Malley, Ahmed Gehad, Jessica E. Teague, Sherrie J. Divito, Robert C. Fuhlbrigge, Pere Puigserver, James G. Krueger, Gökhan S. Hotamışlıgil, Rachael A. Clark, Thomas S. Kupper - Nature 2017 cited by 719
- Melanoma Cell-Intrinsic PD-1 Receptor Functions Promote Tumor Growth
Authors: Sonja Kleffel, Christian Posch, Steven R. Barthel, Hansgeorg Mueller, Christoph Schlapbach, Emmanuella Guenova, Christopher P. Elco, Nayoung Lee, Vikram R. Juneja, Qian Zhan, Christine G. Lian, Rahel Thomi, Wolfram Hoetzenecker, Antonio Cozzio, Reinhard Dummer, Martín C. Mihm, Keith T. Flaherty, Markus H. Frank, Gëorge F. Murphy, Arlene H. Sharpe, Thomas S. Kupper, Tobias Schatton - Cell 2015 cited by 656
- Skin infection generates non-migratory memory CD8+ TRM cells providing global skin immunity
Authors: Xiaodong Jiang, Rachael A. Clark, Luzheng Liu, Amy J. Wagers, Robert C. Fuhlbrigge, Thomas S. Kupper - Nature 2012 cited by 883
- The Vast Majority of CLA+ T Cells Are Resident in Normal Skin
Authors: Rachael A. Clark, Benjamin F. Chong, Nina Mirchandani, Nooshin K. Brinster, Kei-ichi Yamanaka, Rebecca K. Dowgiert, Thomas S. Kupper - The Journal of Immunology 2006 cited by 775
- Human skin is protected by four functionally and phenotypically discrete populations of resident and recirculating memory T cells
Authors: Rei Watanabe, Ahmed Gehad, Chao Yang, Laura Scott, Jessica E. Teague, Christoph Schlapbach, Christopher P. Elco, Victor Huang, Tiago R. Matos, Thomas S. Kupper, Rachael A. Clark - Science Translational Medicine 2015 cited by 559
- Clinically resolved psoriatic lesions contain psoriasis-specific IL-17–producing αβ T cell clones
Authors: Tiago R. Matos, John T. O’Malley, Elizabeth L. Lowry, David Hamm, Ilan R. Kirsch, Harlan Robins, Thomas S. Kupper, James G. Krueger, Rachael A. Clark - Journal of Clinical Investigation 2017 cited by 276
- Viral and metazoan poxins are cGAMP-specific nucleases that restrict cGAS–STING signalling
Authors: James B. Eaglesham, Youdong Pan, Thomas S. Kupper, Philip J. Kranzusch - Nature 2019 cited by 238
- T cells and the skin: from protective immunity to inflammatory skin disorders
Authors: Allen W. Ho, Thomas S. Kupper - Nature reviews. Immunology 2019 cited by 238
- Identification of cells initiating human melanomas
Authors: Tobias Schatton, Gëorge F. Murphy, Natasha Y. Frank, K. Yamaura, Ana Maria Waaga-Gasser, Martin Gasser, Qian Zhan, Stefan Jordan, Lyn M. Duncan, Carsten Weishaupt, Robert C. Fuhlbrigge, Thomas S. Kupper, Mohamed H. Sayegh, Markus H. Frank - Nature 2008 cited by 1,408
- Human Epidermal Langerhans Cells Maintain Immune Homeostasis in Skin by Activating Skin Resident Regulatory T Cells
Authors: Julien Sénéschal, Rachael A. Clark, Ahmed Gehad, Clare Baecher‐Allan, Thomas S. Kupper - Immunity 2012 cited by 435
- Robust tumor immunity to melanoma mediated by interleukin-9–producing T cells
Authors: Rahul Purwar, Christoph Schlapbach, Sheng Xiao, Hong Soon Kang, Wassim Elyaman, Xiaodong Jiang, Anton M. Jetten, Samia J. Khoury, Robert C. Fuhlbrigge, Vijay K. Kuchroo, Rachael A. Clark, Thomas S. Kupper - Nature Medicine 2012 cited by 430
- Assessing the generation of tissue resident memory T cells by vaccines
Authors: E. Rotrosen, Thomas S. Kupper - Nature reviews. Immunology 2023 cited by 81
- The emerging role of resident memory T cells in protective immunity and inflammatory disease
Authors: Chang Ook Park, Thomas S. Kupper - Nature Medicine 2015 cited by 502
- Immune surveillance in the skin: mechanisms and clinical consequences
Authors: Thomas S. Kupper, Robert C. Fuhlbrigge - Nature reviews. Immunology 2004 cited by 784
- Common clonal origin of central and resident memory T cells following skin immunization
Authors: Olivier Gaide, Ryan Emerson, Xiaodong Jiang, Nicholas Gulati, Suzanne T. Nizza, Cindy Desmarais, Harlan Robins, James G. Krueger, Rachael A. Clark, Thomas S. Kupper - Nature Medicine 2015 cited by 284
- Sézary syndrome and mycosis fungoides arise from distinct T-cell subsets: a biologic rationale for their distinct clinical behaviors
Authors: James J. Campbell, Rachael A. Clark, Rei Watanabe, Thomas S. Kupper - Blood 2010 cited by 512
- Interleukin 6 is expressed in high levels in psoriatic skin and stimulates proliferation of cultured human keratinocytes.
Authors: Rachel Grossman, James G. Krueger, D Yourish, Angela Granelli‐Piperno, Doreen Murphy, L T May, Thomas S. Kupper, Pravinkumar B. Sehgal, Alice B. Gottlieb - National Academy of Sciences, Proceedings of the National Academy of Sciences 1989 cited by 851
- TCR sequencing facilitates diagnosis and identifies mature T cells as the cell of origin in CTCL
Authors: Ilan R. Kirsch, Rei Watanabe, John T. O’Malley, David Williamson, Laura-Louise Scott, Christopher P. Elco, Jessica E. Teague, Ahmed Gehad, Elizabeth L. Lowry, Nicole R. LeBoeuf, James G. Krueger, Harlan Robins, Thomas S. Kupper, Rachael A. Clark - Science Translational Medicine 2015 cited by 210
- Staged development of long-lived T-cell receptor αβ TH17 resident memory T-cell population to Candida albicans after skin infection
Authors: Chang Ook Park, Xiujun Fu, Xiaodong Jiang, Youdong Pan, Jessica E. Teague, Nicholas Collins, Tian Tian, John T. O’Malley, Ryan Emerson, Ji Hye Kim, Yookyung Jung, Rei Watanabe, Robert C. Fuhlbrigge, Francis R. Carbone, Thomas Gebhardt, Rachael A. Clark, Charles P. Lin, Thomas S. Kupper - Journal of Allergy and Clinical Immunology 2017 cited by 117
- Metabolic Reprogramming and Longevity of Tissue-Resident Memory T Cells
Authors: Youdong Pan, Thomas S. Kupper - Frontiers in Immunology 2018 cited by 97
- Epicutaneous immunization with modified vaccinia Ankara viral vectors generates superior T cell immunity against a respiratory viral challenge
Authors: Youdong Pan, Luzheng Liu, Tian Tian, Jingxia Zhao, Chang Ook Park, Serena Lofftus, Claire A. Stingley, Yu Yan, Shenglin Mei, Xing Liu, Thomas S. Kupper - npj Vaccines 2021 cited by 76
- The Public Repository of Xenografts Enables Discovery and Randomized Phase II-like Trials in Mice
Authors: Elizabeth C. Townsend, Mark A. Murakami, Alexandra Christodoulou, Amanda L. Christie, Johannes Köster, Tiffany DeSouza, Elizabeth A. Morgan, Scott P. Kallgren, Huiyun Liu, Shuo-Chieh Wu, Olivia D. Plana, Joan Montero, Kristen E. Stevenson, Prakash K. Rao, Raga Vadhi, Michael Andreeff, Philippe Armand, Karen K. Ballen, Patrizia Barzaghi-Rinaudo, Sarah Cahill, Rachael A. Clark, Vesselina G. Cooke, Matthew S. Davids, Daniel J. DeAngelo, David M. Dorfman, Hilary Eaton, Benjamin L. Ebert, Julia Etchin, Brant Firestone, David C. Fisher, Arnold S. Freedman, Ilene Galinsky, Hui Gao, Jacqueline S. Garcia, Francine Garnache‐Ottou, Timothy A. Graubert, Alejandro Gutiérrez, Ensar Halilovic, Marian H. Harris, Zachary T. Herbert, Steven M. Horwitz, Giorgio Inghirami, Andrew M. Intlekofer, Moriko Ito, Shai Izraeli, Eric D. Jacobsen, Caron A. Jacobson, Sébastien Jeay, Irmela Jeremias, Michelle A. Kelliher, Raphael Koch, Marina Konopleva, Nadja Kopp, Steven M. Kornblau, Andrew L. Kung, Thomas S. Kupper, Nicole R. LeBoeuf, Ann S. LaCasce, Emma Lees, Loretta S. Li, A. Thomas Look, Masato Murakami, Markus Müschen, Donna Neuberg, Samuel Y. Ng, Oreofe O. Odejide, Stuart H. Orkin, Rachel R. Paquette, Andrew E. Place, Justine E. Roderick, Jeremy Ryan, Stephen E. Sallan, Brent Shoji, Lewis B. Silverman, Robert J. Soiffer, David P. Steensma, Kimberly Stegmaier, Richard M. Stone, Jérôme Tamburini, Aaron R. Thorner, Paul Van Hummelen, Martha Wadleigh, Marion Wiesmann, Andrew P. Weng, Jens Wuerthner, David A. Williams, Bruce M. Wollison, Andrew A. Lane, Anthony Letai, Monica M. Bertagnolli, Jerome Ritz, Myles Brown, Henry W. Long, Jon C. Aster, Margaret A. Shipp, James D. Griffin, David M. Weinstock - Cancer Cell 2016 cited by 304
- CD8+ T Cells in the Lesional Skin of Atopic Dermatitis and Psoriasis Patients Are an Important Source of IFN-γ, IL-13, IL-17, and IL-22
Authors: DirkJan Hijnen, Edward F. Knol, Yoony Y. J. Gent, Barbara Giovannone, S. J. P. Beijn, Thomas S. Kupper, Carla A.F.M. Bruijnzeel-Koomen, Rachael A. Clark - Journal of Investigative Dermatology 2012 cited by 272
