Timothy A. Springer
Active 1973–2025
- Also published as
- Timothy A Springer
- 329
- Papers
- 112,651
- Citations
- 169
- h-index
- 325
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Medicine52.3%
- Immunology and Microbiology20.6%
- Biochemistry, Genetics and Molecular Biology18.3%
- Neuroscience3.7%
- Engineering1%
- Physics and Astronomy0.7%
- Other3.4%
Topics
- Cell Adhesion Molecules Research10.3%
- T-cell and B-cell Immunology4.5%
- Immune Cell Function and Interaction3.7%
- Immunotherapy and Immune Responses3.7%
- Monoclonal and Polyclonal Antibodies Research3.2%
- Immune Response and Inflammation3%
- Other71.6%
Coauthors
- Michael L. Dustin26
- Chafen Lu25
- Junichi Takagi24
- Motomu Shimaoka20
- Christopher V. Carman16
- Jing Li15
- Thomas Walz14
- Donald E. Staunton13
- R. Alon13
- Jianghai Zhu12
- L J Miller11
- Li-Zhi Mi11
- D C Anderson10
- Jia‐Huai Wang10
- Michael Diamond10
- Xianchi Dong10
- Azucena Salas8
- Francisco Sánchez‐Madrid8
- Jieqing Zhu8
- Margaret L. Hibbs8
- Martin E. Sanders8
- N. Nishida8
- Bing‐Hao Luo7
- Conrad C. Bleul7
All papers
- Latent TGF-β structure and activation
Authors: Minlong Shi, Jianghai Zhu, Rui Wang, Xing Chen, Li-Zhi Mi, Thomas Walz, Timothy A. Springer - Nature 2011 cited by 1,008
- Structural Basis of Integrin Regulation and Signaling
Authors: Bing‐Hao Luo, Christopher V. Carman, Timothy A. Springer - Annual Review of Immunology 2007 cited by 1,637
- Structural Biology and Evolution of the TGF-β Family
Authors: Andrew P. Hinck, Thomas D. Mueller, Timothy A. Springer - Cold Spring Harbor Perspectives in Biology 2016 cited by 377
- Force interacts with macromolecular structure in activation of TGF-β
Authors: Xianchi Dong, Bo Zhao, Roxana E. Iacob, Jianghai Zhu, Adem C. Koksal, Chafen Lu, John R. Engen, Timothy A. Springer - Nature 2017 cited by 285
- Traffic signals for lymphocyte recirculation and leukocyte emigration: The multistep paradigm
Authors: Timothy A. Springer - Cell 1994 cited by 7,010
- Global Conformational Rearrangements in Integrin Extracellular Domains in Outside-In and Inside-Out Signaling
Authors: Junichi Takagi, Benjamin M. Petre, Thomas Walz, Timothy A. Springer - Cell 2002 cited by 1,168
- Adhesion receptors of the immune system
Authors: Timothy A. Springer - Nature 1990 cited by 6,533
- A Milieu Molecule for TGF-β Required for Microglia Function in the Nervous System
Authors: Qin Yan, Brian S. Garrison, Wenjiang Ma, Rui Wang, Aiping Jiang, Jing Li, Meeta Mistry, Roderick T. Bronson, Daria Santoro, Charlotte Franco, Daisy A. Robinton, Beth Stevens, Derrick J. Rossi, Chafen Lu, Timothy A. Springer - Cell 2018 cited by 185
- von Willebrand factor, Jedi knight of the bloodstream
Authors: Timothy A. Springer - Blood 2014 cited by 449
- Monocyte chemoattractant protein 1 acts as a T-lymphocyte chemoattractant.
Authors: Michelle Woldemar Carr, Stephen J. Roth, Ed Luther, Shannon Rose, Timothy A. Springer - National Academy of Sciences, Proceedings of the National Academy of Sciences 1994 cited by 1,221
- Flow-induced elongation of von Willebrand factor precedes tension-dependent activation
Authors: Hongxia Fu, Yan Jiang, Darren Yang, Friedrich Scheiflinger, Wesley P. Wong, Timothy A. Springer - Nature Communications 2017 cited by 210
- A highly efficacious lymphocyte chemoattractant, stromal cell-derived factor 1 (SDF-1)
Authors: Conrad C. Bleul, Robert C. Fuhlbrigge, José M. Casasnovas, Alessandro Aiuti, Timothy A. Springer - The Journal of Experimental Medicine 1996 cited by 1,501
- Structural basis for allostery in integrins and binding to fibrinogen-mimetic therapeutics
Authors: Tsan Sam Xiao, Junichi Takagi, Barry S. Coller, Jia‐Huai Wang, Timothy A. Springer - Nature 2004 cited by 847
- Impaired B-lymphopoiesis, myelopoiesis, and derailed cerebellar neuron migration in CXCR4- and SDF-1-deficient mice
Authors: Qing Ma, Dan Jones, Paul R. Borghesani, Rosalind A. Segal, Takashi Nagasawa, Tadamitsu Kishimoto, Roderick T. Bronson, Timothy A. Springer - National Academy of Sciences, Proceedings of the National Academy of Sciences 1998 cited by 1,682
- Structural determinants of integrin β-subunit specificity for latent TGF-β
Authors: Xianchi Dong, Nathan E. Hudson, Chafen Lu, Timothy A. Springer - Nature Structural & Molecular Biology 2014 cited by 144
- Actin retrograde flow actively aligns and orients ligand-engaged integrins in focal adhesions
Authors: Vinay Swaminathan, Joseph Mathew Kalappurakkal, Shalin B. Mehta, Pontus Nordenfelt, Travis I. Moore, Nobuyasu Koga, David Baker, Rudolf Oldenbourg, Tomomi Tani, Satyajit Mayor, Timothy A. Springer, Clare M. Waterman - National Academy of Sciences, Proceedings of the National Academy of Sciences 2017 cited by 129
- Integrin inside-out signaling and the immunological synapse
Authors: Timothy A. Springer, Michael L. Dustin - Current Opinion in Cell Biology 2011 cited by 393
- Sequence and structure relationships within von Willebrand factor
Authors: Yanfeng Zhou, Edward T. Eng, Jieqing Zhu, Chafen Lu, Thomas Walz, Timothy A. Springer - Blood 2012 cited by 305
- A general chemical principle for creating closure-stabilizing integrin inhibitors
Authors: Fu‐Yang Lin, Jing Li, Yonghua Xie, Jianghai Zhu, Jianghai Zhu, Thi Thu Huong Nguyen, Yonghui Zhang, Jieqing Zhu, Jieqing Zhu, Timothy A. Springer - Cell 2022 cited by 60
- The HIV coreceptors CXCR4 and CCR5 are differentially expressed and regulated on human T lymphocytes
Authors: Conrad C. Bleul, Lijun Wu, James A. Hoxie, Timothy A. Springer, Charles R. Mackay - National Academy of Sciences, Proceedings of the National Academy of Sciences 1997 cited by 1,137
- Conformational equilibria and intrinsic affinities define integrin activation
Authors: Jing Li, Yang Su, Wei Xia, Yan Qin, Martin J. Humphries, Dietmar Vestweber, Carlos Cabañas, Chafen Lu, Timothy A. Springer - The EMBO Journal 2017 cited by 150
- Relating conformation to function in integrin α 5 β 1
Authors: Yang Su, Wei Xia, Jing Li, Thomas Walz, Martin J. Humphries, Dietmar Vestweber, Carlos Cabañas, Chafen Lu, Timothy A. Springer - National Academy of Sciences, Proceedings of the National Academy of Sciences 2016 cited by 142
- Ligand binding initiates single-molecule integrin conformational activation
Authors: Jing Li, Myung Hyun Jo, Jiabin Yan, Taylor Hall, Joon Lee, Uriel López-Sánchez, S. Betty Yan, Taekjip Ha, Timothy A. Springer - Cell 2024 cited by 63
- Single-molecule characterization of subtype-specific β1 integrin mechanics
Authors: Myung Hyun Jo, Jing Li, Valentin Jaumouillé, Yuxin Hao, Jessica Coppola, Jiabin Yan, Clare M. Waterman, Timothy A. Springer, Taekjip Ha - Nature Communications 2022 cited by 47
