William C. Knowler
Active 1977–2025
- Also published as
- William C Knowler
- 239
- Papers
- 54,633
- Citations
- 127
- h-index
- 237
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Medicine68%
- Biochemistry, Genetics and Molecular Biology16.3%
- Dentistry3.2%
- Computer Science2.9%
- Health Professions2.8%
- Neuroscience2.1%
- Other4.7%
Topics
- Diabetes, Cardiovascular Risks, and Lipoproteins5.1%
- Diabetes Treatment and Management3.5%
- Diet and metabolism studies3.1%
- Adipokines, Inflammation, and Metabolic Diseases2.7%
- Birth, Development, and Health2.5%
- Obesity, Physical Activity, Diet2.5%
- Other80.6%
Coauthors
- Peter H. Bennett74
- Robert L. Hanson72
- David J. Pettitt53
- Robert G. Nelson52
- Steven E. Kahn30
- Clifton Bogardus22
- George A. Bray22
- Dana Dabelea20
- David M. Nathan19
- Paul W. Franks19
- Karen Johnson17
- José C. Florez16
- Mohammed Saad16
- Leslie J. Baier15
- Sharon L. Edelstein15
- Helen C. Looker14
- Richard F. Hamman14
- Sayuko Kobes14
- Edward S. Horton13
- Frank L. Greenway13
- John P. Foreyt13
- Kishore M. Gadde13
- Anne L. Peters12
- Kathleen A. Jablonski12
All papers
- Benefits of Modest Weight Loss in Improving Cardiovascular Risk Factors in Overweight and Obese Individuals With Type 2 Diabetes
Authors: Rena R. Wing, Wei Lang, Thomas A. Wadden, Monika M. Safford, William C. Knowler, Alain G. Bertoni, James O. Hill, Frederick L. Brancati, Anne L. Peters, Lynne E. Wagenknecht - Diabetes Care 2011 cited by 1,822
- Association of the magnitude of weight loss and changes in physical fitness with long-term cardiovascular disease outcomes in overweight or obese people with type 2 diabetes: a post-hoc analysis of the Look AHEAD randomised clinical trial
Authors: Edward Gregg, Edward W. Gregg, John M. Jakicic, George L. Blackburn, Paul Bloomquist, George A. Bray, Jeanne M. Clark, Mace Coday, Jeffrey R. Curtis, Caitlin Egan, Mary E. Evans, John P. Foreyt, Gary D. Foster, Helen P. Hazuda, James O. Hill, Edward S. Horton, Van S. Hubbard, Robert W. Jeffery, Karen Johnson, Abbas E. Kitabchi, William C. Knowler, Andrea M. Kriska, Wei Lang, Cora E. Lewis, Maria G. Montez, David M. Nathan, Rebecca H. Neiberg, Jennifer Patricio, Anne Peters, Xavier Pi‐Sunyer, Henry J. Pownall, J. Bruce Redmon, Judith G. Regensteiner, W. Jack Rejeski, Paul M. Ribisl, Monika M. Safford, Kerry J. Stewart, Dace Trence, Thomas A. Wadden, Rena R. Wing - The Lancet Diabetes & Endocrinology 2016 cited by 730
- Vitamin D Supplementation and Prevention of Type 2 Diabetes
Authors: Anastassios G. Pittas, Bess Dawson‐Hughes, Patricia Sheehan, James H. Ware, William C. Knowler, Vanita R. Aroda, Irwin Brodsky, Lisa Ceglia, Chhavi Chadha, Ranee Chatterjee, Cyrus Desouza, Rowena J Dolor, John P. Foreyt, Paul Fuss, Adline Ghazi, Daniel S. Hsia, Karen Johnson, Sangeeta R. Kashyap, Sun H. Kim, Erin S. LeBlanc, Michael R. Lewis, Emilia Liao, Lisa M. Neff, Jason Nelson, Patrick M. O’Neil, Jean Park, Anne L. Peters, Lawrence S. Phillips, Richard E. Pratley, Philip Raskin, Neda Rasouli, David C. Robbins, Clifford J. Rosen, Ellen M. Vickery, Myrlene A. Staten - New England Journal of Medicine 2019 cited by 664
- Effects of Long-term Metformin and Lifestyle Interventions on Cardiovascular Events in the Diabetes Prevention Program and Its Outcome Study
Authors: Ronald Goldberg, Trevor J. Orchard, Jill P. Crandall, Edward J. Boyko, Matthew J. Budoff, Dana Dabelea, Kishore M. Gadde, William C. Knowler, Christine G. Lee, David M. Nathan, Karol E. Watson, Marinella Temprosa - Circulation 2022 cited by 168
- Long-term Metformin Use and Vitamin B12 Deficiency in the Diabetes Prevention Program Outcomes Study
Authors: Vanita R. Aroda, Sharon L. Edelstein, Ronald Goldberg, William C. Knowler, Santica M. Marcovina, Trevor J. Orchard, George A. Bray, David S. Schade, Marinella Temprosa, Neil H. White, Jill P. Crandall - The Journal of Clinical Endocrinology & Metabolism 2016 cited by 522
- Change in albuminuria and subsequent risk of end-stage kidney disease: an individual participant-level consortium meta-analysis of observational studies
Authors: Josef Coresh, Hiddo J.L. Heerspink, Yingying Sang, Kunihiro Matsushita, Johan Ärnlöv, Brad C. Astor, Corri Black, Nigel J. Brunskill, Juan Jesús Carrero, Harold I. Feldman, Caroline S. Fox, Lesley A. Inker, Areef Ishani, Sadayoshi Ito, Simerjot K Jassal, Tsuneo Konta, Kevan R. Polkinghorne, Solfrid Romundstad, Marit D. Solbu, Nikita Stempniewicz, Bénédicte Stengel, Marcello Tonelli, Mitsumasa Umesawa, Sushrut S. Waikar, Chi-Pang Wen, Jack F.M. Wetzels, Mark Woodward, Morgan E. Grams, Csaba P. Kövesdy, Andrew S. Levey, Ron T. Gansevoort, Lawrence J. Appel, Tom Greene, Teresa K. Chen, John Chalmers, Hisatomi Arima, Vlado Perkovic, Adeera Levin, Ognjenka Djurdjev, Mila Tang, Joseph V. Nally, Sankar D. Navaneethan, Jesse D. Schold, Misghina Weldegiorgis, William G. Herrington, Margaret Smith, Chun-Shuo Hsu, Shih‐Jen Hwang, Alex R. Chang, H. Lester Kirchner, Jamie A. Green, Kevin Ho, Angharad Marks, Gordon Prescott, Laura E. Clark, Nick Fluck, Varda Shalev, Gabriel Chodick, Peter J. Blankestijn, Arjan van Zuilen, Jan AJG van den Brand, Mark J. Sarnak, Erwin Böttinger, Girish N. Nadkarni, Stephen G. Ellis, Rajiv Nadukuru, Marie Metzger, Martin Flamant, Pascal Houillier, Jean‐Philippe Haymann, Marc Froissart, Timothy Kenealy, Raina Elley, John Collins, Paul Drury, John K. Cuddeback, Elizabeth L. Ciemins, Rich Stempniewicz, Robert G. Nelson, William C. Knowler, Stephen J. L. Bakker, Rupert Major, James Medcalf, David Shepherd, Elizabeth Barrett‐Connor, Jaclyn Bergstrom, Joachim H. Ix, Miklos Z. Molnar, Keiichi Sumida, Dick de Zeeuw, Barry M. Brenner, Abdul Rashid Qureshi, Carl‐Gustaf Elinder, Björn Runesson, Marie Evans, Mårten Segelmark, Maria Stendahl, Staffan Schön, David Naimark, Navdeep Tangri and 38 more - The Lancet Diabetes & Endocrinology 2019 cited by 320
- Using the ADAP Learning Algorithm to Forecast the Onset of Diabetes Mellitus
Authors: Jack W. Smith, James E. Everhart, Will Dickson, William C. Knowler, R.S. Johannes - 1988 cited by 748
- Albuminuria Testing in Hypertension and Diabetes: An Individual-Participant Data Meta-Analysis in a Global Consortium
Authors: Jung‐Im Shin, Alex R. Chang, Morgan E. Grams, Josef Coresh, Shoshana H. Ballew, Aditya Surapaneni, Kunihiro Matsushita, Henk J.G. Bilo, Juan Jesús Carrero, Gabriel Chodick, Kenn B. Daratha, Simerjot K Jassal, Girish N. Nadkarni, Robert G. Nelson, Christoph Nowak, Nikita Stempniewicz, Keiichi Sumida, Jamie P. Traynor, Mark Woodward, Yingying Sang, Ron T. Gansevoort, John Chalmers, Katherine R. Tuttle, Radica Z. Alicic, Sterling McPherson, Cami R. Jones, Gurmukteshwar Singh, Jamie Green, H. Lester Kirchner, Varda Shalev, Erwin P. Böttinger, Ruth J. F. Loos, Stephen B. Ellis, John K. Cuddeback, Elizabeth L. Ciemins, Emily Carbonara, Stephan Dunning, William C. Knowler, Helen C. Looker, Lyane M. Kieneker, Stephan J. L. Bakker, Hans L. Hillege, Pim van der Harst, Simerjot K Jassal, Jacklyn Bergstrom, Joachim H. Ix, Csaba P. Kövesdy, Praveen K. Potukuchi, Marco Trevisan, Carl Gustaf Elinder, Björn Wettermark, Johan Ärnlöv, Patrick B. Mark, Peter Thomson, Colin Geddes, Gijs W.D. Landman, Kornelis J. J. van Hateren, Nanne Kleefstra, Orlando M. Gutiérrez, Tsuneo Konta, Andrew S. Levey, Kevan R. Polkinghorne, Elke Schäffner, Jingsha Chen, Aditya Surapeneni - Hypertension 2021 cited by 140
- The Effect of Lifestyle Intervention and Metformin on Preventing or Delaying Diabetes Among Women With and Without Gestational Diabetes: The Diabetes Prevention Program Outcomes Study 10-Year Follow-Up
Authors: Vanita R. Aroda, Costas A. Christophi, Sharon L. Edelstein, P. Zhang, William H. Herman, Elizabeth Barrett‐Connor, Linda M. Delahanty, Maria G. Montez, Ronald T. Ackermann, X. Zhuo, William C. Knowler, Robert E. Ratner - The Journal of Clinical Endocrinology & Metabolism 2015 cited by 467
- Intratrial Exposure to Vitamin D and New-Onset Diabetes Among Adults With Prediabetes: A Secondary Analysis From the Vitamin D and Type 2 Diabetes (D2d) Study
Authors: Bess Dawson‐Hughes, Myrlene A. Staten, William C. Knowler, Jason Nelson, Ellen M. Vickery, Erin S. LeBlanc, Lisa M. Neff, Jean Park, Anastassios G. Pittas - Diabetes Care 2020 cited by 190
- Reduction in Weight and Cardiovascular Disease Risk Factors in Individuals With Type 2 Diabetes
Authors: Xavier Pi-Sunyer, Xavier Pi‐Sunyer, George L. Blackburn, Frederick L. Brancati, George A. Bray, Renee Bright, Jeanne M. Clark, Jeffrey M. Curtis, Mark A. Espeland, John P. Foreyt, Kathryn Graves, Steven M. Haffner, Barbara Harrison, James O. Hill, Edward S. Horton, John M. Jakicic, Robert W. Jeffery, Karen Johnson, Steven E. Kahn, David E. Kelley, Abbas E. Kitabchi, William C. Knowler, Cora E. Lewis, Barbara J. Maschak-Carey, Brenda K. Montgomery, David M. Nathan, Jennifer Patricio, Anne L. Peters, J. Bruce Redmon, Rebecca S. Reeves, Donna H. Ryan, Monika M. Safford, Brent Van Dorsten, Thomas A. Wadden, Lynne E. Wagenknecht, Jacqueline Wesche-Thobaben, Rena R. Wing - Diabetes Care 2007 cited by 1,533
- Childhood Obesity, Other Cardiovascular Risk Factors, and Premature Death
Authors: Paul W. Franks, Robert L. Hanson, William C. Knowler, Maurice L. Sievers, Peter H. Bennett, Helen C. Looker - New England Journal of Medicine 2010 cited by 1,372
- Insulin Resistance and Insulin Secretory Dysfunction as Precursors of Non-Insulin-Dependent Diabetes Mellitus: Prospective Studies of Pima Indians
Authors: Stephen Lillioja, David M. Mott, Maximilian Spraul, R Ferraro, James E. Foley, Éric Ravussin, William C. Knowler, Peter H. Bennett, Clifton Bogardus - New England Journal of Medicine 1993 cited by 1,512
- Metformin for diabetes prevention: insights gained from the Diabetes Prevention Program/Diabetes Prevention Program Outcomes Study
Authors: Vanita R. Aroda, William C. Knowler, Jill P. Crandall, Leigh Perreault, Sharon L. Edelstein, Susan Jeffries, Mark E. Molitch, F. Xavier Pi‐Sunyer, Christine Darwin, Brandy M. Heckman‐Stoddard, Marinella Temprosa, Steven E. Kahn, David M. Nathan - Diabetologia 2017 cited by 196
- Regression From Prediabetes to Normal Glucose Regulation and Prevalence of Microvascular Disease in the Diabetes Prevention Program Outcomes Study (DPPOS)
Authors: Leigh Perreault, Qing Pan, Emily B. Schroeder, Rita R. Kalyani, George A. Bray, Samuel Dagogo‐Jack, Neil H. White, Ronald Goldberg, Steven E. Kahn, William C. Knowler, Nestoras Mathioudakis, Dana Dabelea, George A. Bray, Kishore M. Gadde, Annie Chatellier, Jennifer Arceneaux, Amber Dragg, Crystal Duncan, Frank L. Greenway, Daniel S. Hsia, Erma Levy, Monica Lockett, Donna H. Ryan, David A. Ehrmann, Margaret J. Matulik, Kirsten Czech, Catherine DeSandre, Barry J. Goldstein, Kevin Furlong, Kellie A. Smith, Wendi Wildman, Constance Pepe, Ronald Goldberg, Jeanette Calles, Juliet Ojito, Sumaya Castillo-Florez, Hermes Flórez, Anna Giannella, Olga Lara, Beth Veciana, Steven M. Haffner, Helen P. Hazuda, Maria G. Montez, Kathy Hattaway, Carlos Lorenzo, Arlene Martinez, Tatiana Walker, Richard F. Hamman, Dana Dabelea, Lisa Testaverde, Denise Anderson, Alexis Bouffard, Tonya Jenkins, Dione Lenz, Leigh Perreault, David W. Price, Sheila C. Steinke, Edward S. Horton, Catherine S. Poirier, Kati Swift, Enrique Caballero, Barbara Fargnoli, Ashley Guidi, Mathew Guido, Sharon D. Jackson, Lori Lambert, Kathleen E. Lawton, Sarah Ledbury, Jessica Sansoucy, Jeanne Spellman, Steven E. Kahn, Brenda K. Montgomery, Wilfred Y. Fujimoto, Robert H. Knopp, Edward W. Lipkin, Ivy Morgan-Taggart, Anne Murillo, Lonnese Taylor, April Thomas, Elaine C. Tsai, Dace Trence, Abbas E. Kitabchi, Samuel Dagogo‐Jack, Mary E. Murphy, Laura Taylor, Jennifer Dolgoff, Debra Clark, Uzoma N. Ibebuogu, Helen Lambeth, Harriet Ricks, Lily M.K. Rutledge, Judith E. Soberman, Mark E. Molitch, Boyd E. Metzger, Mariana K. Johnson, Mimi M. Giles, Diane Larsen, Samsam C. Pen, David M. Nathan, Mary Larkin and 196 more - Diabetes Care 2019 cited by 104
- The Effect of Intentional Weight Loss on Fracture Risk in Persons With Diabetes: Results From the Look AHEAD Randomized Clinical Trial
Authors: Karen Johnson, George A. Bray, Lawrence J. Cheskin, Jeanne M. Clark, Caitlin Egan, John P. Foreyt, Katelyn R Garcia, Stephen P. Glasser, Frank L. Greenway, Edward W. Gregg, Helen P. Hazuda, Andrea L. Hergenroeder, James O. Hill, Edward S. Horton, John M. Jakicic, Robert W. Jeffery, Steven E. Kahn, William C. Knowler, Cora E. Lewis, Marsha Miller, Maria G. Montez, David M. Nathan, Jennifer Patricio, Anne L. Peters, Xavier Pi‐Sunyer, Henry J. Pownall, David M. Reboussin, J. Bruce Redmon, Helmut O. Steinberg, Thomas A. Wadden, Lynne E. Wagenknecht, Rena R. Wing, Catherine Womack, Susan Z Yanovski, Zhang Ping, Ann V. Schwartz, for the Look AHEAD Study Group - Journal of Bone and Mineral Research 2017 cited by 100
- Racial/ethnic and socioeconomic disparities in the use of newer diabetes medications in the Look AHEAD study
Authors: Ahmed Elhussein, Andrea Anderson, Michael P. Bancks, Mace Coday, William C. Knowler, Anne L. Peters, Elizabeth M. Vaughan, Nisa M. Maruthur, Jeanne M. Clark, Scott J. Pilla - The Lancet Regional Health - Americas 2021 cited by 93
- Intensive Weight Loss Intervention and Cancer Risk in Adults with Type 2 Diabetes: Analysis of the Look AHEAD Randomized Clinical Trial
Authors: Hsin‐Chieh Yeh, John P. Bantle, Maria Cassidy‐Begay, George L. Blackburn, George A. Bray, Tim Byers, Jeanne M. Clark, Mace Coday, Caitlin Egan, Mark A. Espeland, John P. Foreyt, Katelyn R Garcia, Valerie Goldman, Edward W. Gregg, Helen P. Hazuda, Louise Hesson, James O. Hill, Edward S. Horton, John M. Jakicic, Robert W. Jeffery, Karen Johnson, Steven E. Kahn, William C. Knowler, Mary Korytkowski, Anne Kure, Cora E. Lewis, Christos S. Mantzoros, Maria Meacham, Maria G. Montez, David M. Nathan, Nicholas M. Pajewski, Jennifer Patricio, Anne L. Peters, F. Xavier Pi‐Sunyer, Henry J. Pownall, Donna H. Ryan, Monika M. Safford, Rebecca L. Sedjo, Helmut Steinburg, Mara Z. Vitolins, Thomas A. Wadden, Lynne E. Wagenknecht, Rena R. Wing, Antonio C. Wolff, Holly R. Wyatt, Susan Z. Yanovski - Obesity 2020 cited by 81
- Effect of Metformin and Lifestyle Interventions on Mortality in the Diabetes Prevention Program and Diabetes Prevention Program Outcomes Study
Authors: Christine G. Lee, Brandy M. Heckman‐Stoddard, Dana Dabelea, Kishore M. Gadde, David A. Ehrmann, Leslie Ford, Philip C. Prorok, Edward J. Boyko, F. Xavier Pi‐Sunyer, Amisha Wallia, William C. Knowler, Jill P. Crandall, Marinella Temprosa, George A. Bray, Kishore M. Gadde, Iris W. Culbert, Jennifer Arceneaux, Annie Chatellier, Amber Dragg, Catherine M. Champagne, Crystal Duncan, Barbara Eberhardt, Frank L. Greenway, Fonda G. Guillory, April A. Herbert, Michael L. Jeffirs, Betty M. Kennedy, Erma Levy, Monica Lockett, Jennifer C. Lovejoy, Laura H. Morris, Lee E. Melancon, Donna H. Ryan, Deborah A. Sanford, Kenneth G. C. Smith, Lisa L. Smith, Julia A. St. Amant, Richard T. Tulley, Paula C. Vicknair, Donald Williamson, Jeffery J. Zachwieja, Kenneth S. Polonsky, Janet Tobian, David A. Ehrmann, Margaret J. Matulik, Karla A. Temple, Bart Clark, Kirsten Czech, Catherine DeSandre, Brittnie Dotson, Ruthanne Hilbrich, Wylie McNabb, Ann R. Semenske, Jose F. Caro, Kevin Furlong, Barry J. Goldstein, Pamela G. Watson, Kellie A. Smith, Jewel Mendoza, Marsha Simmons, Wendi Wildman, Renee Liberoni, John Spandorfer, Constance Pepe, Richard P. Donahue, Ronald Goldberg, Ronald J. Prineas, Jeanette Calles, Anna Giannella, Patricia M. Rowe, Juliet Sanguily, Paul Cassanova-Romero, Sumaya Castillo-Florez, Hermes Flórez, Rajesh Garg, Lascelles Kirby, Olga Lara, Carmen Larreal, Valerie McLymont, Jadell Mendez, Arlette Perry, Patrice G. Saab, Bertha Veciana, Steven M. Haffner, Helen P. Hazuda, Maria G. Montez, Kathy Hattaway, Juan Isaac, Carlos Lorenzo, Arlene Martinez, Monica Salazar, Tatiana Walker, Dana Dabelea, Richard F. Hamman, Patricia V. Nash, Sheila C. Steinke, Lisa Testaverde, Jennifer Truong, Denise Anderson, Larry B. Ballonoff and 565 more - Diabetes Care 2021 cited by 99
- Regression From Pre-Diabetes to Normal Glucose Regulation in the Diabetes Prevention Program
Authors: Leigh Perreault, Steven E. Kahn, Costas A. Christophi, William C. Knowler, Richard F. Hamman - Diabetes Care 2009 cited by 211
- New-Onset Diabetes After COVID-19
Authors: Sun H. Kim, Ipsa Arora, Daniel S. Hsia, William C. Knowler, Erin S. LeBlanc, Eleftherios Mylonakis, Richard E. Pratley, Anastassios G. Pittas - The Journal of Clinical Endocrinology & Metabolism 2023 cited by 51
- TCF7L2 Polymorphisms and Progression to Diabetes in the Diabetes Prevention Program
Authors: José C. Florez, Kathleen A. Jablonski, Nick Bayley, Toni I. Pollin, Paul I. W. de Bakker, Alan R. Shuldiner, William C. Knowler, David M. Nathan, David Altshuler - New England Journal of Medicine 2006 cited by 837
- Long-Term Weight Loss With Metformin or Lifestyle Intervention in the Diabetes Prevention Program Outcomes Study
Authors: John W. Apolzan, Elizabeth M. Venditti, Sharon L. Edelstein, William C. Knowler, Dana Dabelea, Edward J. Boyko, Xavier Pi‐Sunyer, Rita R. Kalyani, Paul W. Franks, Preethi Srikanthan, Kishore M. Gadde - Annals of Internal Medicine 2019 cited by 155
- Reduced Rate of Energy Expenditure as a Risk Factor for Body-Weight Gain
Authors: Éric Ravussin, Stephen Lillioja, William C. Knowler, Laurent Christin, D. Freymond, William G.H. Abbott, Vicky L Boyce, Barbara V. Howard, Clifton Bogardus - New England Journal of Medicine 1988 cited by 1,222
