William W. Hauswirth
Active 1971–2023
- 144
- Papers
- 26,248
- Citations
- 96
- h-index
- 143
- i10-index
Citations
Citation sources
Countries
Institutions
- University of Florida1.9%
- University of Pennsylvania1.4%
- University College London1.3%
- Harvard University1.2%
- Inserm1.1%
- Johns Hopkins University0.9%
- Other92.2%
Fields
- Biochemistry, Genetics and Molecular Biology64.1%
- Medicine18.7%
- Neuroscience12.2%
- Immunology and Microbiology1.3%
- Agricultural and Biological Sciences1.1%
- Engineering0.6%
- Other2%
Topics
- Retinal Development and Disorders11.4%
- Retinal Diseases and Treatments6.1%
- Virus-based gene therapy research6%
- Mitochondrial Function and Pathology4.1%
- CRISPR and Genetic Engineering3.9%
- Photoreceptor and optogenetics research2.6%
- Other65.9%
Coauthors
- Sanford L. Boye32
- Alfred S. Lewin28
- Vince A. Chiodo24
- Artur V. Cideciyan18
- Samuel G. Jacobson17
- Jijing Pang14
- Qiuhong Li14
- John Guy12
- Alexander Sumaroka11
- Astra Dinculescu10
- Tomás S. Alemán10
- Wen‐Tao Deng10
- William A. Beltran10
- Alejandro J. Román9
- Gustavo D. Aguirre9
- Kenneth I. Berns9
- Shalesh Kaushal9
- Terence R. Flotte9
- András M. Komáromy8
- Małgorzata Świder8
- Seok Hong Min8
- Sharon Schwartz8
- Simone Iwabe8
- Thomas J. Conlon8
All papers
- Dual AAV-mediated gene therapy restores hearing in a DFNB9 mouse model
Authors: Omar Akil, Frank M. Dyka, Charlotte Calvet, Alice Emptoz, Ghizlène Lahlou, Sylvie Nouaille, Jacques Boutet de Monvel, Jean‐Pierre Hardelin, William W. Hauswirth, Paul Avan, Christine Petit, Saaïd Safieddine, Lawrence R. Lustig - National Academy of Sciences, Proceedings of the National Academy of Sciences 2019 cited by 294
- DICER1 Loss and Alu RNA Induce Age-Related Macular Degeneration via the NLRP3 Inflammasome and MyD88
Authors: Valeria Tarallo, Yoshio Hirano, Bradley D. Gelfand, Sami Dridi, Nagaraj Kerur, Young‐Hee Kim, Won Gil Cho, Hiroki Kaneko, Benjamin J. Fowler, Sasha Bogdanovich, Romulo Albuquerque, William W. Hauswirth, Vince A. Chiodo, Jennifer F. Kugel, James A. Goodrich, Steven L. Ponicsan, Gautam Chaudhuri, Michael P. Murphy, Joshua L. Dunaief, Balamurali K. Ambati, Yuichiro Ogura, Jae Wook Yoo, Dong Ki Lee, Patrick Provost, David R. Hinton, Gabriel Núñez, Judit Baffi, Mark E. Kleinman, Jayakrishna Ambati - Cell 2012 cited by 600
- Treatment of Leber Congenital Amaurosis Due to RPE65 Mutations by Ocular Subretinal Injection of Adeno-Associated Virus Gene Vector: Short-Term Results of a Phase I Trial
Authors: William W. Hauswirth, Tomás S. Alemán, Shalesh Kaushal, Artur V. Cideciyan, Sharon Schwartz, Lili Wang, Thomas J. Conlon, Sanford L. Boye, Terence R. Flotte, Barry J. Byrne, Samuel G. Jacobson - Human Gene Therapy 2008 cited by 947
- DICER1 deficit induces Alu RNA toxicity in age-related macular degeneration
Authors: Hiroki Kaneko, Sami Dridi, Valeria Tarallo, Bradley D. Gelfand, Benjamin J. Fowler, Won Gil Cho, Mark E. Kleinman, Steven L. Ponicsan, William W. Hauswirth, Vince A. Chiodo, Katalin Karikó, Jae Wook Yoo, Dong-ki Lee, Majda Hadziahmetovic, Ying Song, Smita Misra, Gautam Chaudhuri, F. William Buaas, Robert E. Braun, David R. Hinton, Qing Zhang, Hans E. Grossniklaus, Jan Provis, Michele C. Madigan, Ann H. Milam, Nikki L. Justice, Romulo Albuquerque, Alexander D. Blandford, Sasha Bogdanovich, Yoshio Hirano, Jassir Witta, Elaine Fuchs, Dan R. Littman, Balamurali K. Ambati, Charles M. Rudin, Mark M. W. Chong, Patrick Provost, Jennifer F. Kugel, James A. Goodrich, Joshua L. Dunaief, Judit Baffi, Jayakrishna Ambati - Nature 2011 cited by 619
- A Muscleblind Knockout Model for Myotonic Dystrophy
Authors: Rahul Kanadia, Karen A. Johnstone, Ami Mankodi, Codrin Lungu, Charles A. Thornton, Douglas W Esson, Adrian M. Timmers, William W. Hauswirth, Maurice S. Swanson - Science 2003 cited by 750
- Treatment of retinitis pigmentosa due to MERTK mutations by ocular subretinal injection of adeno-associated virus gene vector: results of a phase I trial
Authors: Nicola G. Ghazi, Emad B. Abboud, Sawsan R. Nowilaty, Hisham Alkuraya, Abdulrahman Alhommadi, Huimin Cai, Rui Hou, Wen‐Tao Deng, Sanford L. Boye, Abdulrahman Almaghamsi, Fahad Al Saikhan, Hassan Al-Dhibi, David G. Birch, Christopher Chung, Dilek Çolak, Matthew M. LaVail, Douglas Vollrath, Kirsten Erger, Wen‐qiu Wang, Thomas J. Conlon, Kang Zhang, William W. Hauswirth, Fowzan S. Alkuraya - Human Genetics 2016 cited by 240
- Novel Properties of Tyrosine-mutant AAV2 Vectors in the Mouse Retina
Authors: Hilda Petrs‐Silva, Astra Dinculescu, Qiuhong Li, Wen‐Tao Deng, Jijing Pang, Seok-Hong Min, Vince A. Chiodo, Andy W. Neeley, L. Govindasamy, Antonette Bennett, Mavis Agbandje‐McKenna, Zhong Li, Baozheng Li, Giridhara R. Jayandharan, Arun Srivastava, Alfred S. Lewin, William W. Hauswirth - Molecular Therapy 2010 cited by 265
- Functional genomic screening identifies dual leucine zipper kinase as a key mediator of retinal ganglion cell death
Authors: Derek S. Welsbie, Zhiyong Yang, Yan Ge, Katherine L. Mitchell, Xinrong Zhou, Scott E. Martin, Cynthia Berlinicke, László Hackler, John A. Fuller, Jie Fu, Li-Hui Cao, Bing Han, Douglas S. Auld, Tian Xue, Syu-ichi Hirai, Lucie Germain, Caroline Simard-Bisson, Richard Blouin, Judy V. Nguyen, Chung-ha O. Davis, Ray A. Enke, Sanford L. Boye, Shannath L. Merbs, Nicholas Marsh‐Armstrong, William W. Hauswirth, Aaron DiAntonio, Robert W. Nickells, James Inglese, Justin Hanes, King‐Wai Yau, Harry A. Quigley, Donald J. Zack - National Academy of Sciences, Proceedings of the National Academy of Sciences 2013 cited by 271
- Gene Therapy for Leber Hereditary Optic Neuropathy
Authors: John Guy, William J. Feuer, Janet L. Davis, Vittorio Porciatti, Phillip Gonzalez, Rajeshwari D. Koilkonda, Huijun Yuan, William W. Hauswirth, Byron L. Lam - Ophthalmology 2017 cited by 201
- Human retinal gene therapy for Leber congenital amaurosis shows advancing retinal degeneration despite enduring visual improvement
Authors: Artur V. Cideciyan, Samuel G. Jacobson, William A. Beltran, Alexander Sumaroka, Małgorzata Świder, Simone Iwabe, Alejandro J. Román, Melani B. Olivares, Sharon Schwartz, András M. Komáromy, William W. Hauswirth, Gustavo D. Aguirre - National Academy of Sciences, Proceedings of the National Academy of Sciences 2013 cited by 440
- Dual ABCA4 -AAV Vector Treatment Reduces Pathogenic Retinal A2E Accumulation in a Mouse Model of Autosomal Recessive Stargardt Disease
Authors: Frank M. Dyka, Laurie L. Molday, Vince A. Chiodo, Robert S. Molday, William W. Hauswirth - Human Gene Therapy 2019 cited by 58
- Improvement and Decline in Vision with Gene Therapy in Childhood Blindness
Authors: Samuel G. Jacobson, Artur V. Cideciyan, Alejandro J. Román, Alexander Sumaroka, Sharon Schwartz, Elise Héon, William W. Hauswirth - New England Journal of Medicine 2015 cited by 377
- A Comprehensive Review of Retinal Gene Therapy
Authors: Sanford L. Boye, Sanford L. Boye, Alfred S. Lewin, William W. Hauswirth - Molecular Therapy 2013 cited by 262
- SOD2 Knockdown Mouse Model of Early AMD
Authors: Verline Justilien, Jijing Pang, Kutralanathan Renganathan, Xianquan Zhan, John W. Crabb, So Ra Kim, Janet R. Sparrow, William W. Hauswirth, Alfred S. Lewin - Investigative Ophthalmology & Visual Science 2007 cited by 236
- Effect of CNTF on Retinal Ganglion Cell Survival in Experimental Glaucoma
Authors: Mary Ellen Pease, Donald J. Zack, Cynthia Berlinicke, Kristen Bloom, Frances E. Cone, Yuxia Wang, Ronald L. Klein, William W. Hauswirth, Harry A. Quigley - Investigative Ophthalmology & Visual Science 2009 cited by 223
- Gene therapy restores vision in a canine model of childhood blindness
Authors: Gregory M. Acland, Geoffrey K. Aguirre, Jharna Ray, Qí Zhāng, Tomás S. Alemán, Artur V. Cideciyan, Susan E. Pearce-Kelling, Vibha Anand, Yong Zeng, Albert M. Maguire, Samuel G. Jacobson, William W. Hauswirth, Jean Bennett - Nature Genetics 2001 cited by 1,195
- High-efficiency Transduction of the Mouse Retina by Tyrosine-mutant AAV Serotype Vectors
Authors: Hilda Petrs‐Silva, Astra Dinculescu, Qiuhong Li, Seok-Hong Min, Vince A. Chiodo, Jijing Pang, Zhong Li, Sergei Zolotukhin, Arun Srivastava, Alfred S. Lewin, William W. Hauswirth - Molecular Therapy 2008 cited by 394
- Virally delivered Channelrhodopsin-2 Safely and Effectively Restores Visual Function in Multiple Mouse Models of Blindness
Authors: M. Mehdi Doroudchi, Kenneth P. Greenberg, Jianwen Liu, Kimberly A Silka, Edward S. Boyden, Jennifer A. Lockridge, A. Cyrus Arman, Janani Ramesh, Sanford L. Boye, Sanford L. Boye, Gabriel M. Gordon, Benjamin C Matteo, Alapakkam P. Sampath, William W. Hauswirth, Alan Horsager - Molecular Therapy 2011 cited by 277
- Results at 2 Years after Gene Therapy for RPE65-Deficient Leber Congenital Amaurosis and Severe Early-Childhood–Onset Retinal Dystrophy
Authors: Richard G. Weleber, Mark E. Pennesi, David J. Wilson, Shalesh Kaushal, Laura Erker, Lauren Jensen, Maureen T. McBride, Terence R. Flotte, Margaret Humphries, Roberto Calcedo, William W. Hauswirth, Jeffrey D. Chulay, J. Timothy Stout - Ophthalmology 2016 cited by 218
- Gene delivery to mitochondria by targeting modified adenoassociated virus suppresses Leber’s hereditary optic neuropathy in a mouse model
Authors: Hong Yu, Rajeshwari D. Koilkonda, Tsung-Han Chou, Vittorio Porciatti, Sacide S. Ozdemir, Vince A. Chiodo, Sanford L. Boye, Sanford L. Boye, William W. Hauswirth, Alfred S. Lewin, John Guy - National Academy of Sciences, Proceedings of the National Academy of Sciences 2012 cited by 190
- Intraocular route of AAV2 vector administration defines humoral immune response and therapeutic potential.
Authors: Qiuhong Li, Rehae Miller, Pingyang Han, Jijing Pang, Astra Dinculescu, Vince A. Chiodo, William W. Hauswirth - 2008 cited by 188
- Dual Adeno-Associated Virus Vectors Result in Efficient In Vitro and In Vivo Expression of an Oversized Gene, MYO7A
Authors: Frank M. Dyka, Sanford L. Boye, Vince A. Chiodo, William W. Hauswirth, Sanford L. Boye - Human Gene Therapy Methods 2014 cited by 127
- Human gene therapy for RPE65 isomerase deficiency activates the retinoid cycle of vision but with slow rod kinetics
Authors: Artur V. Cideciyan, Tomás S. Alemán, Sanford L. Boye, Sharon Schwartz, Shalesh Kaushal, Alejandro J. Román, Jijing Pang, Alexander Sumaroka, Elizabeth A. M. Windsor, James M. Wilson, Terence R. Flotte, Gerald A. Fishman, Elise Héon, Edwin M. Stone, Barry J. Byrne, Samuel G. Jacobson, William W. Hauswirth - National Academy of Sciences, Proceedings of the National Academy of Sciences 2008 cited by 664
- Gene Therapy with Brain-Derived Neurotrophic Factor As a Protection: Retinal Ganglion Cells in a Rat Glaucoma Model
Authors: Keith R. Martin, Harry A. Quigley, Donald J. Zack, Hana Levkovitch-Verbin, Jennifer L. Kielczewski, Danielle Valenta, Lisa A. Baumrind, Mary Ellen Pease, Ronald L. Klein, William W. Hauswirth - Investigative Ophthalmology & Visual Science 2003 cited by 363
