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Xi‐Ping Huang

Active 1992–2025

Also published as
Xi-Ping Huang
104
Papers
25,272
Citations
72
h-index
101
i10-index

Citations

Citations per year for Xi‐Ping Huang1967: 1 citations1982: 1 citations1985: 1 citations1987: 7 citations1992: 1 citations1993: 2 citations1994: 26 citations1995: 14 citations1996: 9 citations1997: 14 citations1998: 23 citations1999: 11 citations2000: 13 citations2001: 14 citations2002: 12 citations2003: 12 citations2004: 7 citations2005: 10 citations2006: 7 citations2007: 5 citations2008: 9 citations2009: 9 citations2010: 22 citations2011: 55 citations2012: 122 citations2013: 221 citations2014: 261 citations2015: 274 citations2016: 288 citations2017: 365 citations2018: 362 citations2019: 897 citations2020: 1,570 citations2021: 1,728 citations2022: 1,202 citations2023: 920 citations2024: 1,245 citations2025: 653 citations2026: 34 citations1968–1981: no citations, so these years are not shown1983–1984: no citations, so these years are not shown1986: no citations, so this year is not shown1988–1991: no citations, so these years are not shown

Citation sources

Countries

World map of the countries and regions citing this authorUnited States: 3,874 citing papers, 28.7% of this breakdownChina: 1,607 citing papers, 11.9% of this breakdownUnited Kingdom: 854 citing papers, 6.3% of this breakdownGermany: 688 citing papers, 5.1% of this breakdownCanada: 548 citing papers, 4.1% of this breakdownFrance: 464 citing papers, 3.4% of this breakdownItaly: 462 citing papers, 3.4% of this breakdownIndia: 423 citing papers, 3.1% of this breakdownJapan: 367 citing papers, 2.7% of this breakdownSpain: 299 citing papers, 2.2% of this breakdownAustralia: 295 citing papers, 2.2% of this breakdownSwitzerland: 277 citing papers, 2.1% of this breakdown
0%28.7%Other 24.8%

Institutions

Fields

  • Biochemistry, Genetics and Molecular Biology33.3%
  • Medicine31.1%
  • Neuroscience13.6%
  • Computer Science10%
  • Immunology and Microbiology3.3%
  • Psychology2.2%
  • Other6.5%

Topics

  • Receptor Mechanisms and Signaling6.6%
  • Computational Drug Discovery Methods5.6%
  • SARS-CoV-2 and COVID-19 Research4.9%
  • Neuropeptides and Animal Physiology3.6%
  • COVID-19 Clinical Research Studies3.1%
  • Neuroscience and Neuropharmacology Research3%
  • Other73.2%

Coauthors

All papers

Open in search
  1. A SARS-CoV-2 protein interaction map reveals targets for drug repurposing

    Authors: David E. Gordon, Gwendolyn Μ. Jang, Mehdi Bouhaddou, Jiewei Xu, Kirsten Obernier, Kris M. White, Matthew J. O’Meara, Veronica V. Rezelj, Jeffrey Guo, Danielle L. Swaney, Tia A. Tummino, Ruth Hüttenhain, Robyn M. Kaake, Alicia Richards, Beril Tutuncuoglu, Helene Foussard, Jyoti Batra, Kelsey M. Haas, Maya Modak, Minkyu Kim, Paige Haas, Benjamin J. Polacco, Hannes Braberg, Jacqueline M. Fabius, Manon Eckhardt, Margaret Soucheray, Melanie J. Bennett, Merve Çakır, Michael McGregor, Qiongyu Li, Bjoern Meyer, Ferdinand Roesch, Thomas Vallet, Alice Mac Kain, Lisa Miorin, Elena Moreno, Zun Zar Chi Naing, Yuan Zhou, Shiming Peng, Ying Shi, Ziyang Zhang, Wenqi Shen, Ilsa T. Kirby, James E. Melnyk, John S. Chorba, Kevin Lou, Shizhong Dai, Inigo Barrio‐Hernandez, Danish Memon, Claudia Hernández-Armenta, Jiankun Lyu, Christopher J.P. Mathy, Tina Perica, Kala Bharath Pilla, Sai J. Ganesan, Daniel J. Saltzberg, Ramachandran Rakesh, Liu Xi, Sara B. Rosenthal, Lorenzo Calviello, Srivats Venkataramanan, José Liboy-Lugo, Yizhu Lin, Xi‐Ping Huang, Yongfeng Liu, Stephanie A. Wankowicz, Markus‐Frederik Bohn, Maliheh Safari, Fatima S. Ugur, Cassandra Koh, Nastaran Sadat Savar, Quang Tran, Djoshkun Shengjuler, Sabrina Johanna Fletcher, Michael C. O’Neal, Yiming Cai, Jason C. Chang, David Broadhurst, Saker Klippsten, Phillip P. Sharp, Nicole A. Wenzell, Duygu Kuzuoğlu‐Öztürk, Hao‐Yuan Wang, Raphael Trenker, Janet M. Young, Devin A. Cavero, Joseph Hiatt, Theodore L. Roth, Ujjwal Rathore, Advait Subramanian, Julia Noack, Mathieu Hubert, Robert M. Stroud, Alan D. Frankel, Oren S. Rosenberg, Kliment A. Verba, David A. Agard, Mélanie Ott, Michael Emerman, Natalia Jura and 25 more - Nature 2020 cited by 4,888

  2. Synthon-based ligand discovery in virtual libraries of over 11 billion compounds

    Authors: Arman A. Sadybekov, Anastasiia Sadybekov, Yongfeng Liu, Christos Iliopoulos‐Tsoutsouvas, Xi‐Ping Huang, Julie E. Pickett, Blake Houser, Nilkanth Patel, Ngan K. Tran, Fei Tong, Nikolai Zvonok, Manish K. Jain, Olena Savych, Dmytro S. Radchenko, Spyros P. Nikas, Nicos A. Petasis, Yurii S. Moroz, Bryan L. Roth, Alexandros Makriyannis, Vsevolod Katritch - Nature 2021 cited by 433

  3. NMDAR inhibition-independent antidepressant actions of ketamine metabolites

    Authors: Panos Zanos, Ruin Moaddel, Patrick J. Morris, Polymnia Georgiou, Jonathan Fischell, Gregory I. Elmer, Manickavasagom Alkondon, Peixiong Yuan, Heather J. Pribut, N. Singh, Katina S. S. Dossou, Yuhong Fang, Xi‐Ping Huang, Cheryl L. Mayo, Irving W. Wainer, Edson X. Albuquerque, Scott M. Thompson, Craig J. Thomas, Carlos A. Zarate, Todd D. Gould - Nature 2016 cited by 1,619

  4. PRESTO-Tango as an open-source resource for interrogation of the druggable human GPCRome

    Authors: Wesley K. Kroeze, Maria F. Sassano, Xi‐Ping Huang, Katherine Lansu, John D. McCorvy, Patrick M. Giguère, Noah Sciaky, Bryan L. Roth - Nature Structural & Molecular Biology 2015 cited by 785

  5. Bespoke library docking for 5-HT2A receptor agonists with antidepressant activity

    Authors: Anat Levit Kaplan, Danielle N. Confair, Kuglae Kim, Ximena Barros-Álvarez, Ramona M. Rodriguiz, Yang Ying, Oh Sang Kweon, Tao Che, John D. McCorvy, David N. Kamber, James P. Phelan, Luan Carvalho Martins, Vladimir M. Pogorelov, Jeffrey F. DiBerto, Samuel T. Slocum, Xi‐Ping Huang, Manish K. Jain, Michael J. Robertson, Ouliana Panova, Alpay B. Seven, Autumn Q. Wetsel, William C. Wetsel, John J. Irwin, Georgios Skiniotis, Brian K. Shoichet, Bryan L. Roth, Jonathan A. Ellman - Nature 2022 cited by 252

  6. Structure-based discovery of opioid analgesics with reduced side effects

    Authors: Aashish Manglik, Henry Lin, Dipendra K. Aryal, John D. McCorvy, Daniela Dengler, Gregory Corder, Anat Levit, Ralf C. Kling, Viachaslau Bernat, Harald Hübner, Xi-Ping Huang, Maria F. Sassano, Patrick M. Giguère, Stefan Löber, Da Duan, Grégory Scherrer, Brian K. Kobilka, Peter Gmeiner, Bryan L. Roth, Brian K. Shoichet - Nature, Nat. 2016 cited by 972

  7. Virtual discovery of melatonin receptor ligands to modulate circadian rhythms

    Authors: Reed M. Stein, Hye Jin Kang, John D. McCorvy, Grant C. Glatfelter, Anthony Jones, Tao Che, Samuel T. Slocum, Xi‐Ping Huang, Olena Savych, Yurii S. Moroz, Benjamin Stauch, Linda C. Johansson, Vadim Cherezov, Terry Kenakin, John J. Irwin, Brian K. Shoichet, Bryan L. Roth, Margarita L. Dubocovich - Nature 2020 cited by 317

  8. Automated design of ligands to polypharmacological profiles

    Authors: Jérémy Besnard, G.F. Ruda, Vincent Setola, Keren Abecassis, Ramona M. Rodriguiz, Xi‐Ping Huang, Suzanne Norval, Maria F. Sassano, Antony I. Shin, Lauren Webster, Frederick R. C. Simeons, Laste Stojanovski, Annik Prat, Nabil G. Seidah, Daniel B. Constam, G. Richard Bickerton, Kevin D. Read, William C. Wetsel, Ian H. Gilbert, Bryan L. Roth, Andrew L. Hopkins - Nature 2012 cited by 854

  9. Structures of the σ2 receptor enable docking for bioactive ligand discovery

    Authors: Assaf Alon, Jiankun Lyu, João M. Bráz, Tia A. Tummino, Veronica Craik, Matthew J. O’Meara, Chase M. Webb, Dmytro S. Radchenko, Yurii S. Moroz, Xi‐Ping Huang, Yongfeng Liu, Bryan L. Roth, John J. Irwin, Allan I. Basbaum, Brian K. Shoichet, Andrew C. Kruse - Nature 2021 cited by 194

  10. Structural insights into the human D1 and D2 dopamine receptor signaling complexes

    Authors: Youwen Zhuang, Peiyu Xu, Chunyou Mao, Lei Wang, B. Krumm, X. Edward Zhou, Sijie Huang, Heng Liu, Xi Cheng, Xi‐Ping Huang, Dandan Shen, Ting-Hai Xu, Yongfeng Liu, Yue Wang, Jia Guo, Yi Jiang, Hualiang Jiang, Karsten Melcher, Bryan L. Roth, Yan Zhang, Cheng Zhang, H. Eric Xu - Cell 2021 cited by 264

  11. Structure, function and pharmacology of human itch GPCRs

    Authors: Can Cao, Hye Jin Kang, Isha Singh, He Chen, Chengwei Zhang, Wenlei Ye, Byron W. Hayes, Jing Liu, Ryan H. Gumpper, Brian J. Bender, Samuel T. Slocum, B. Krumm, Katherine Lansu, John D. McCorvy, Wesley K. Kroeze, Justin G. English, Jeffrey F. DiBerto, Reid H. J. Olsen, Xi‐Ping Huang, Shicheng Zhang, Yongfeng Liu, Kuglae Kim, Joel Karpiak, Lily Yeh Jan, Soman N. Abraham, Jian Jin, Brian K. Shoichet, Jonathan F. Fay, Bryan L. Roth - Nature 2021 cited by 224

  12. Structure-based discovery of nonopioid analgesics acting through the α 2A -adrenergic receptor

    Authors: Elissa A. Fink, Jun Xu, Harald Hübner, João M. Bráz, Philipp Seemann, Charlotte Avet, Veronica Craik, Dorothée Weikert, Maximilian F. Schmidt, Chase M. Webb, Nataliya A. Tolmachova, Yurii S. Moroz, Xi‐Ping Huang, Chakrapani Kalyanaraman, Stefan Gahbauer, Geng Chen, Zheng Liu, Matthew P. Jacobson, John J. Irwin, Michel Bouvier, Yang Du, Brian K. Shoichet, Allan I. Basbaum, Peter Gmeiner - Science 2022 cited by 152

  13. Discovery of Human Signaling Systems: Pairing Peptides to G Protein-Coupled Receptors

    Authors: Simon R. Foster, Alexander S. Hauser, Line Vedel, Ryan T. Strachan, Xi‐Ping Huang, Ariana C. Gavin, Sushrut D. Shah, Ajay P. Nayak, Linda M. Haugaard‐Kedström, Raymond B. Penn, Bryan L. Roth, Hans Bräuner‐Osborne, David E. Gloriam - Cell 2019 cited by 267

  14. Structure-based discovery of conformationally selective inhibitors of the serotonin transporter

    Authors: Isha Singh, Anubha Seth, Christian B. Billesbølle, João M. Bráz, Ramona M. Rodriguiz, Kasturi Roy, Bethlehem Bekele, Veronica Craik, Xi‐Ping Huang, Danila Boytsov, Vladimir M. Pogorelov, Parnian Lak, Henry O’Donnell, Walter Sandtner, John J. Irwin, Bryan L. Roth, Allan I. Basbaum, William C. Wetsel, Aashish Manglik, Brian K. Shoichet, Gary Rudnick - Cell 2023 cited by 99

  15. Allosteric ligands for the pharmacologically dark receptors GPR68 and GPR65

    Authors: Xi-Ping Huang, Joel Karpiak, Wesley K. Kroeze, Hu Zhu, Xin Chen, Sheryl S. Moy, Kara A. Saddoris, Viktoriya D. Nikolova, Martilias S. Farrell, Sheng Wang, Thomas J. Mangano, Deepak A. Deshpande, Alice Jiang, Raymond B. Penn, Jian Jin, Beverly H. Koller, Terry Kenakin, Brian K. Shoichet, Bryan L. Roth - Nature, Nat. 2015 cited by 287

  16. Structure of the human κ-opioid receptor in complex with JDTic

    Authors: Huixian Wu, Daniel Wacker, Mauro Mileni, Vsevolod Katritch, Gye Won Han, Eyal Vardy, Wei Liu, Aaron A. Thompson, Xi‐Ping Huang, F. Ivy Carroll, S. Wayne Mascarella, Richard B. Westkaemper, Philip D. Mosier, Bryan L. Roth, Vadim Cherezov, Raymond C. Stevens - Nature 2012 cited by 878

  17. A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells

    Authors: Masoud Vedadi, Dalia Baršytė-Lovejoy, Feng Liu, Sylvie Rival‐Gervier, Abdellah Allali‐Hassani, Viviane Labrie, Tim J. Wigle, Peter A. DiMaggio, Gregory A. Wasney, Alena Siarheyeva, Aiping Dong, W. Tempel, Sun-Chong Wang, Xin Chen, Irene Chau, Thomas J Mangano, Xi‐Ping Huang, Catherine Simpson, Samantha G Pattenden, Jacqueline L Norris, Dmitri Kireev, Ashutosh Tripathy, A.M. Edwards, Bryan L. Roth, William P Janzen, Benjamin A. García, Artūras Petronis, James Ellis, Peter J. Brown, Stephen V. Frye, C.H. Arrowsmith, Jian Jin - Nature Chemical Biology 2011 cited by 531

  18. Structure of the Nanobody-Stabilized Active State of the Kappa Opioid Receptor

    Authors: Tao Che, Susruta Majumdar, Saheem A. Zaidi, Pauline W. Ondachi, John D. McCorvy, Sheng Wang, Philip D. Mosier, Rajendra Uprety, Eyal Vardy, B. Krumm, Gye Won Han, Ming-Yue Lee, Els Pardon, Jan Steyaert, Xi‐Ping Huang, Ryan T. Strachan, Alexandra R. Tribo, Gavril W. Pasternak, F. Ivy Carroll, Raymond C. Stevens, Vadim Cherezov, Vsevolod Katritch, Daniel Wacker, Bryan L. Roth - Cell 2018 cited by 377

  19. Molecular control of δ-opioid receptor signalling

    Authors: Gustavo Fenalti, Patrick M. Giguère, Vsevolod Katritch, Xi‐Ping Huang, Aaron A. Thompson, Vadim Cherezov, Bryan L. Roth, Raymond C. Stevens - Nature 2014 cited by 503

  20. An Orally Bioavailable Chemical Probe of the Lysine Methyltransferases EZH2 and EZH1

    Authors: Kyle D. Konze, Anqi Ma, Fengling Li, Dalia Baršytė-Lovejoy, Trevor Parton, Christopher J. MacNevin, Feng Liu, Cen Gao, Xi‐Ping Huang, Ekaterina Kuznetsova, Marie Rougié, Alice Jiang, Samantha G. Pattenden, Jacqueline L. Norris, Lindsey I. James, Bryan L. Roth, Peter J. Brown, Stephen V. Frye, C.H. Arrowsmith, Klaus M. Hahn, Gang Greg Wang, Masoud Vedadi, Jian Jin - ACS Chemical Biology 2013 cited by 466

  21. A New DREADD Facilitates the Multiplexed Chemogenetic Interrogation of Behavior

    Authors: Eyal Vardy, J. Elliott Robinson, Chia Li, Reid H. J. Olsen, Jeffrey F. DiBerto, Patrick M. Giguère, Flori M. Sassano, Xi‐Ping Huang, Hu Zhu, Daniel J. Urban, Kate White, Joseph E. Rittiner, Nicole A. Crowley, Kristen E. Pleil, Christopher M. Mazzone, Philip D. Mosier, Juan Song, Thomas L. Kash, C. J. Malanga, Michael J. Krashes, Bryan L. Roth - Neuron 2015 cited by 398

  22. Mechanism of dopamine binding and allosteric modulation of the human D1 dopamine receptor

    Authors: Youwen Zhuang, B. Krumm, Huibing Zhang, X. Edward Zhou, Yue Wang, Xi‐Ping Huang, Yongfeng Liu, Xi Cheng, Yi Jiang, Hualiang Jiang, Cheng Zhang, Wei Yi, Bryan L. Roth, Yan Zhang, H. Eric Xu - Cell Research 2021 cited by 99

  23. Neurotensin Receptor Allosterism Revealed in Complex with a Biased Allosteric Modulator

    Authors: B. Krumm, Jeffrey F. DiBerto, Reid H. J. Olsen, Hye Jin Kang, Samuel T. Slocum, Shicheng Zhang, Ryan T. Strachan, Xi‐Ping Huang, Lauren M. Slosky, Anthony B. Pinkerton, Lawrence S Barak, Marc G. Caron, Terry Kenakin, Jonathan F. Fay, Bryan L. Roth - Biochemistry 2023 cited by 71

  24. A Simple Representation of Three-Dimensional Molecular Structure

    Authors: Seth D. Axen, Xi‐Ping Huang, Elena L. Cáceres, Leo Gendelev, Bryan L. Roth, Michael J. Keiser - Journal of Medicinal Chemistry 2017 cited by 146