Infective Endocarditis in Childhood: 2015 Update

Authors: Robert S. Baltimore, Michael H. Gewitz, Larry M. Baddour, Lee B. Beerman, Mary Anne Jackson, Peter B. Lockhart, Elfriede Pahl, Gordon E. Schutze, Stanford T. Shulman, Rodney E. Willoughby - Circulation 2015 cited by 387

Epidemiology and Clinical Findings of IE in ChildrenIn a previous report, IE occurred less often in children than in adults and accounted for approximately 1 in 1280 (0.78 per 1000) pediatric admissions per year from 1972 to 1982 at a referral insitution. 4In a recent multicenter report, 5 the annual incidence rate in the United States was between approximately 0.05 and 0.12 cases per 1000 pediatric admissions from 2003 to 2010, without a significant trend.][7][8] This may be related to improved survival among children who are at risk for endocarditis, such as those with CHD (with or without surgery) and hospitalized newborn infants.