Time course EPI of human brain function during task activation

Authors: Peter A. Bandettini, Eric C. Wong, R. Scott Hinks, Ronald S. Tikofsky, James S. Hyde - Magnetic Resonance in Medicine 1992 cited by 1,949

Using gradient-echo echo-planar MRI, a local signal increase of 4.3 +/- 0.3% is observed in the human brain during task activation, suggesting a local decrease in blood deoxyhemoglobin concentration and an increase in blood oxygenation. Images highlighting areas of signal enhancement temporally correlated to the task are created.