Allosteric inhibition of SHP2 phosphatase inhibits cancers driven by receptor tyrosine kinases

Authors: Ying-Nan P. Chen, Matthew J. LaMarche, Ho Man Chan, Peter Fekkes, Jorge García‐Fortanet, Michael Acker, Brandon Antonakos, Christine Hiu-Tung Chen, Zhouliang Chen, Vesselina G. Cooke, Jason R. Dobson, Zhan Deng, Fei Feng, Brant Firestone, Michelle Fodor, Cary Fridrich, Hui Gao, Denise C. Grünenfelder, Huai-Xiang Hao, Jaison Jacob, Samuel B. Ho, Kathy Hsiao, Kang Zhao, Rajesh Karki, Mitsunori Kato, Jay F. Larrow, Laura R. La Bonte, François Lenoir, Gang Liu, Shumei Liu, Dyuti Majumdar, Matthew J. Meyer, Mark Palermo, Lawrence Perez, Minying Pu, Edmund V. Price, Christopher Quinn, Subarna Shakya, Michael D. Shultz, Joanna Slisz, K. Venkatesan, Ping Wang, Markus Warmuth, Sarah Williams, Guizhi Yang, Jing Yuan, Ji-Hu Zhang, Ping Zhu, Timothy M. Ramsey, Nicholas Keen, William R. Sellers, Travis Stams, Pascal D. Fortin - Nature 2016 cited by 946