Cancer cachexia in adult patients: ESMO Clinical Practice Guidelines☆

Authors: Jann Arends, Florian Strasser, Silvia Gonella, Tora S. Solheim, Clelia Madeddu, Paula Ravasco, Loredana Buonaccorso, M.A.E. de van der Schueren, Christine Baldwin, Martin Chasen, Carla Ripamonti - ESMO Open 2021 cited by 505

Cachexia remains an underdiagnosed and undertreated, complex condition which includes ‘objective’ components (e.g. inadequate food intake, weight loss, inactivity, loss of muscle mass and metabolic derangements, inducing catabolism)1,2 and ‘subjective’ components (e.g. anorexia, early satiety, taste alterations, chronic nausea, distress, fatigue and loss of concentration). Approximately half of all patients with advanced cancer experience cachexia.