Endometriosis

Authors: Serdar E. Bulun - New England Journal of Medicine, NEJM 2009 cited by 1,746

This review emphasizes the participation of estrogen and inflammation in the development of endometriosis. A feedback cycle in which prostaglandins and aromatase activity are prominent allows for the persistence of endometriotic tissue. Knowledge of this cycle has important implications for the treatment of endometriosis.