FABP5 promotes lymph node metastasis in cervical cancer by reprogramming fatty acid metabolism

Authors: Chunyu Zhang, Yuandong Liao, Pan Liu, Qiqiao Du, Yanchun Liang, Shiyin Ooi, Shuhang Qin, Shanyang He, Shuzhong Yao, Wei Wang - Theranostics 2020 cited by 185

: Our findings highlight a FA metabolism-dependent mechanism of FABP5-induced LNM. Moreover, the expression and biological function of FABP5 can be regulated by miR-144-3p in hypoxia. Our study identifies FABP5 as a potential diagnostic biomarker and therapeutic target for LNM in CCa.