Antioxidant activity of mesenchymal stem cell-derived extracellular vesicles restores hippocampal neurons following seizure damage

Authors: Qiang Luo, Panpan Xian, Tian Wang, Shengxi Wu, Tangna Sun, Wenting Wang, Bo Wang, Hao Yang, Yanping Yang, Han Wang, Weiping Liu, Qianfa Long - Theranostics 2021 cited by 103

We have shown that MSC-EVs facilitate the reconstruction of hippocampal neurons associated with the Nrf2 defense system in response to oxidative insults. Our study highlights the clinical value of EV-therapy in neurological disorders such as seizures.