NAD + repletion improves muscle function in muscular dystrophy and counters global PARylation

Authors: Dongryeol Ryu, Hongbo Zhang, Eduardo R. Ropelle, Vincenzo Sorrentino, Davi A. G. Mázala, Laurent Mouchiroud, Philip Marshall, Matthew D. Campbell, Amir S. Ali, Gary Knowels, Stéphanie Bellemin, Shama R. Iyer, Xu Wang, Karim Gariani, Anthony A. Sauve, Carles Cantó, Kevin E. Conley, Ludivine Walter, Richard M. Lovering, Eva R. Chin, Bernard J. Jasmin, David J. Marcinek, Keir J. Menzies, Johan Auwerx - Science Translational Medicine 2016 cited by 251

may benefit patients with muscular dystrophies or other neuromuscular degenerative conditions characterized by the PARP/NNMT gene expression signatures.