CD133-directed CAR T cells for advanced metastasis malignancies: A phase I trial

Authors: Yao Wang, Meixia Chen, Zhiqiang Wu, Chuan Tong, Hanren Dai, Yelei Guo, Yang Liu, Jianhua Huang, Haiyan Lv, Can Luo, Kaichao Feng, Qingming Yang, Xiaolei Li, Weidong Han - OncoImmunology 2018 cited by 328

lesions during this term. Analysis of biopsied tissues by immunohistochemistry showed CD133+ cells were eliminated after CART-133 infusions. This trial showed the feasibility, controllable toxicities, and effective activity of CART-133 transfer for treating patients with CD133-postive and late-stage metastasis malignancies.