Live Lactobacillus acidophilus alleviates ulcerative colitis via the SCFAs/mitophagy/NLRP3 inflammasome axis

Authors: Pei Li, Guoping Chen, Jiaxian Zhang, Chaoying Pei, Ying Chen, Jing Gong, Song Deng, Kaiwei Cai, Haiyan Li, Dawei Wang, Baochun Shen, Zhiyong Xie, Qiongfeng Liao - Food & Function 2022 cited by 67

The live Lactobacillus acidophilus (La) alleviated colitis by ameliorating intestinal barrier and suppressing inflammation. SCFAs modulated and enriched by La promoted the mitophagy/NLRP3 inflammasome pathway, which helped to improve gut functions.