Bone infection site targeting nanoparticle-antibiotics delivery vehicle to enhance treatment efficacy of orthopedic implant related infection

Authors: Bin’en Nie, Shicheng Huo, Xinhua Qu, Jingjing Guo, Xi Liu, Qimin Hong, You Wang, Jianping Yang, Bing Yue - Bioactive Materials 2022 cited by 80

, the growth of bacteria was evidently inhibited without cytotoxicity, thus realizing the early treatment of implant-related infection. Hence, the bone-and-bacteria dual-targeted molecule-modified NPs may target bacteria-infected bone sites and act as ideal candidates for the therapy of orthopedic implant-related infections.