Safety and pharmacodynamics of an engineered E. coli Nissle for the treatment of phenylketonuria: a first-in-human phase 1/2a study

Authors: Marja Puurunen, Jerry Vockley, Shawn Searle, Stephanie Sacharow, John A. Phillips, William S. Denney, Benjamin D. Goodlett, David A. Wagner, Larry Blankstein, Mary Joan Castillo, Mark R. Charbonneau, Vincent M. Isabella, Vasu V. Sethuraman, Richard J. Riese, Caroline Kurtz, Aoife M. Brennan - Nature Metabolism 2021 cited by 160