htsget: a protocol for securely streaming genomic data

Authors: Jerome Kelleher, Mike C. Lin, C H Albach, Ewan Birney, Robert M. Davies, Marina Gourtovaia, David Glazer, Cristina González, David K. Jackson, Aaron S. Kemp, John Marshall, Andrew Nowak, Alexander Senf, Jaime M. Tovar-Corona, Alexander Vikhorev, Thomas Keane, GA4GH Streaming Task Team, Dixie B. Baker, Vadim Zalunin, Angel Pizarro, Richard Durbin, Mark Diekhans, Edmon Begoli, Ilia Tulchinsky, Heng Li, Rishi Nag, Stephen Keenan, Ilkka Lappalainen, Jim Robinson - Bioinformatics 2018 cited by 28

Summary: Standardized interfaces for efficiently accessing high-throughput sequencing data are a fundamental requirement for large-scale genomic data sharing. We have developed htsget, a protocol for secure, efficient and reliable access to sequencing read and variation data. We demonstrate four independent client and server implementations, and the results of a comprehensive interoperability demonstration. Availability and implementation: http://samtools.github.io/hts-specs/htsget.html. Supplementary information: Supplementary data are available at Bioinformatics online.