Gut Microbiota and Colonization Resistance against Bacterial Enteric Infection

Authors: Quinten R. Ducarmon, Romy D. Zwittink, Bastian Hornung, Willem van Schaik, Vincent B. Young, Ed J. Kuijper - Microbiology and Molecular Biology Reviews 2019 cited by 538

The gut microbiome is critical in providing resistance against colonization by exogenous microorganisms. The mechanisms via which the gut microbiota provide colonization resistance (CR) have not been fully elucidated, but they include secretion of antimicrobial products, nutrient competition, support of gut barrier integrity, and bacteriophage deployment.