Viral Encounters with 2′,5′-Oligoadenylate Synthetase and RNase L during the Interferon Antiviral Response
RNA cleavage is a fundamental host response for controlling viral infections in both plants and animals ([26][1]). In higher vertebrates, this process is often regulated by interferons (IFNs), a family of antiviral cytokines discovered 50 years ago ([50][2]). One of the principal IFN antiviral