In Silico Genotyping of Escherichia coli Isolates for Extraintestinal Virulence Genes by Use of Whole-Genome Sequencing Data

Authors: Anna Maria Malberg Tetzschner, James R. Johnson, Brian Johnston, Ole Lund, Flemming Scheutz - Journal of Clinical Microbiology 2020 cited by 421

Extraintestinal pathogenic Escherichia coli (ExPEC) is the leading cause in humans of urinary tract infection and bacteremia. The previously published web tool VirulenceFinder ( http://cge.cbs.dtu.dk/services/VirulenceFinder/ ) uses whole-genome sequencing (WGS) data for in silico characterization of E. coli isolates and enables researchers and clinical health personnel to quickly extract and interpret virulence-relevant information from WGS data.