ApoE4 markedly exacerbates tau-mediated neurodegeneration in a mouse model of tauopathy

Authors: Alzheimer’s Disease Neuroimaging Initiative, Yang Shi, Kaoru Yamada, Shane A. Liddelow, Scott Smith, Lingzhi Zhao, Wenjie Luo, Richard Tsai, Salvatore Spina, Lea T. Grinberg, Julio C. Rojas, Gilbert Gallardo, Kairuo Wang, Joseph Roh, Grace O. Robinson, Mary Beth Finn, Hong Jiang, Patrick M. Sullivan, Caroline Baufeld, Michael W. Wood, Courtney L. Sutphen, Lena McCue, Chengjie Xiong, Jorge L. Del‐Aguila, John C. Morris, Carlos Cruchaga, A. Fagan, Bruce L. Miller, Adam L. Boxer, William W. Seeley, Oleg Butovsky, Ben A. Barres, S. Paul, David M. Holtzman - Nature 2017 cited by 1,257