Glutamine promotes antibiotic uptake to kill multidrug-resistant uropathogenic bacteria

Authors: Xianliang Zhao, Zhuang‐Gui Chen, Tian‐Ci Yang, Ming Jiang, Jie Wang, Zhi-xue Cheng, Manjun Yang, Jiaxin Zhu, Tiantuo Zhang, Hui Li, Bo Peng, Xuan‐xian Peng - Science Translational Medicine 2021 cited by 237

elevated antibiotic resistance in antibiotic-sensitive strains. In addition, glutamine retarded the development of ampicillin resistance. These results may facilitate future development of effective approaches for preventing or managing chronic, multidrug-resistant bacterial infections, bacterial persistence, and difficult-to-treat bacterial biofilms.