C−F Bond Activation by Silylium Cation/Phosphine Frustrated Lewis Pairs: Mono‐Hydrodefluorination of PhCF3, PhCF2H and Ph2CF2

Authors: Ian Mallov, Adam J. Ruddy, Hui Zhu, Stefan Grimme, Douglas W. Stephan - Chemistry - A European Journal 2017 cited by 76

Abstract Single defluorination of aryl polyfluoromethyl functionalities is achieved by both intra‐ and intermolecular silylium cation/phosphine Lewis pairs. Phosphine‐captured aryl fluoromethyl cations are then treated with Brønsted base to complete the first mono‐hydrodefluorinations of PhCF 3 , Ph 2 CF 2 , and PhCF 2 .