Use of Opsonophagocytosis for Serological Evaluation of Pneumococcal Vaccines

Authors: Sandra Romero‐Steiner, Carl E. Frasch, George M. Carlone, Roland A. Fleck, David Goldblatt, Moon H. Nahm - Clinical and Vaccine Immunology 2006 cited by 214

Since 2000, when a pneumococcal conjugate vaccine (Prevnar) was introduced, pneumococcal infections in the United States among children have been dramatically reduced. The conjugate vaccine elicits antibodies to pneumococcal capsular polysaccharide, and these antibodies protect the host by