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Mn2+ Directly Activates cGAS and Structural Analysis Suggests Mn2+ Induces a Noncanonical Catalytic Synthesis of 2′3′-cGAMP

Authors: Zhen Zhao, Zhixing Ma, Bo Wang, Yukun Guan, Xiao‐Dong Su, Zhengfan Jiang - Cell Reports 2020 cited by 313

as a cGAS activator that initiates noncanonical 2'3'-cGAMP synthesis.

Mn2+ Directly Activates cGAS and Structural Analysis Suggests Mn2+ Induces a Noncanonical Catalytic Synthesis of 2′3′-cGAMP | Litlas