A flexible multiplexed immunosensor for point-of-care in situ wound monitoring

Authors: Yuji Gao, Dat T. Nguyen, Trifanny Yeo, Su Bin Lim, Wei Xian Tan, Leigh Madden, Lin Jin, Ji Yong Kenan Long, Fazila Aloweni, Yi Jia Angela Liew, Mandy Li Ling Tan, Shin Yuh Ang, Sivagame D O Maniya, Ibrahim Abdelwahab, Kian Ping Loh, Chia‐Hung Chen, David L. Becker, David I. Leavesley, John S. Ho, Chwee Teck Lim - Science Advances 2021 cited by 270

), and physicochemical parameters (temperature and pH) with a microfluidic wound exudate collector and flexible electronics for wireless, smartphone-based data readout. We demonstrate in situ multiplexed monitoring in a mouse wound model and also profile wound exudates from patients with venous leg ulcers. This technology may facilitate more timely and personalized wound management to improve chronic wound healing outcomes.